Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kerri A. Ball"'
Autor:
Junhee Park, Jie Li, John P. Mayer, Kerri A. Ball, Jiayi Wu, Catherine Hall, Domenico Accili, Michael H. B. Stowell, Xiao-chen Bai, Eunhee Choi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Genetic mutations of insulin receptor (IR) cause severe insulin resistance syndromes with no current treatment or cure. Here, the authors present that insulin-independent IR activation mechanism by peptide agonist which activate non-functional IR mut
Externí odkaz:
https://doaj.org/article/3c42c5abf8ed4d0ca0fe281573c41d63
Autor:
Helen Simpson, Alejandro Ramirez, Eric Bunker, William M. Old, Xun Liu, Steven E. Guard, Jeremy Jacobsen, Julie A. Reisz, Robert E. Sievers, Michael H. B. Stowell, Travis Nemkov, Angelo D'Alessandro, Zachary C. Poss, Douglas A. Chapnick, S. J. Coleman, Kristofor J. Webb, Kerri A. Ball, Christopher C. Ebmeier
Publikováno v:
Molecular & Cellular Proteomics. 21:100262
The non-psychoactive cannabinoid, cannabidiol (CBD), is FDA-approved for treatment of two drug-resistant epileptic disorders, and is seeing increased use among the general public, yet the mechanisms that underlie its therapeutic effects and side-effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83afaa2585790c998c9e70d3edf73072
https://doi.org/10.1016/j.mcpro.2022.100262
https://doi.org/10.1016/j.mcpro.2022.100262
Autor:
Kristofor J. Webb, Kerri A. Ball, Xiaoyun Ding, William M. Old, Yonghui Ding, Yu Gao, Michael H. B. Stowell, Angelo D'Alessandro
Thermal shift assays (TSAs) have been extensively used to study thermodynamics of proteins and provide an efficient means to assess protein-ligand binding or protein-protein interactions. However, existing TSAs have limitations, such as being time co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895149b96e7e9e92dbf229f06d89507b
http://arxiv.org/abs/2108.04935
http://arxiv.org/abs/2108.04935
Autor:
Michael H. B. Stowell, William M. Old, S. J. Coleman, Jeremy Jacobsen, Kerri A. Ball, Kristofor J. Webb
Identifying protein targets directly bound by drug molecules within living systems remains challenging. Here we present the isothermal shift assay, iTSA, for rapid identification of drug targets. Compared with thermal proteome profiling, a prevailing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da134a3957560818fcb46e96dd605c06
Autor:
Yu Gao, Michael H. B. Stowell, Angelo D'Alessandro, William M. Old, Kristofor J. Webb, Xiaoyun Ding, Yonghui Ding, Kerri A. Ball
Publikováno v:
Small. 16:2070224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78a4152c16b7b3304b2bb297a34dc9a
https://doi.org/10.1002/smll.202070224
https://doi.org/10.1002/smll.202070224
Autor:
William M. Old, Igor Kogut, Kerri E Ball, Ganna Bilousova, Michael K Klymkowsky, Jeremy Jacobsen, Christopher C. Ebmeier, Tristan D. McClure-Begley
SUMMARYHuman trisomy 21 (Down syndrome) is the most common genetic cause of intellectual disability, and is associated with complex perturbations in protein expression during development. Brain region-specific alterations in neuronal density and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947b12ec961cc8ea5cfcf6999f2c4a80
https://doi.org/10.1101/315317
https://doi.org/10.1101/315317
We have employed label-free quantitative proteomics of wild-type and Alzheimer’s disease (AD) model mice synaptosomes to investigate proteomic changes occurring during AD progression as a prelude to analysis in humans. More than 4000 proteins were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f0d497904006039e671e44d047c3d3
Autor:
Apresio K. Fajrial, Michael H. B. Stowell, William M. Old, Yung-Cheng Lee, Xiaoyun Ding, Nakul Sridhar, Kerri A. Ball, Biddut Bhattacharjee, Michael J. Miles
Publikováno v:
Micromachines
Volume 10
Issue 12
Volume 10
Issue 12
In recent years, microfluidic devices have become an important tool for use in lab-on-a-chip processes, including drug screening and delivery, bio-chemical reactions, sample preparation and analysis, chemotaxis, and separations. In many such processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1648f45b7a047c658702dc31c773f487
https://doi.org/10.3390/mi10120839
https://doi.org/10.3390/mi10120839
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 102:182-191
Cytochrome c oxidase (Cco) has been reported to be a receptor for some of the beneficial effects of low intensity visible and near-infrared light on cells and tissues. Here, we have explored the role of low intensity light in affecting a newly descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1952fb23062d6088aff7760ad03eed
https://doi.org/10.1016/j.jphotobiol.2010.12.002
https://doi.org/10.1016/j.jphotobiol.2010.12.002
Autor:
Robert O, Poyton, Kerri A, Ball
Publikováno v:
Discovery medicine. 11(57)
Currently, light therapies are widely used in both human and veterinarian medicine. The application of light to clinical therapeutics includes: photodynamic therapy, used to kill cancer cells; UVA therapies, used to treat a variety of skin diseases;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::434d4367840706658641ad3a0e3ab87e
https://pubmed.ncbi.nlm.nih.gov/21356170
https://pubmed.ncbi.nlm.nih.gov/21356170