Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kerly Fernanda Mesquita Pasqualoto"'
Autor:
Luciana de Araújo Pimenta, Evandro L. Duarte, Gabriel S. Vignoli Muniz, Kerly Fernanda Mesquita Pasqualoto, Marcos Roberto de Mattos Fontes, M. Teresa Lamy, Sandra Coccuzzo Sampaio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The important pharmacological actions of Crotoxin (CTX) on macrophages, the main toxin in the venom of Crotalus durissus terrificus, and its important participation in the control of different pathophysiological processes, have been demonstr
Externí odkaz:
https://doaj.org/article/03e95d123a8a4cfc8d436f3c84350d12
Autor:
Andrea Borrego, Francesca Colombo, Jean Gabriel de Souza, José Ricardo Jensen, Alice Dassano, Rocco Piazza, Barbara Anaís Rodrigues dos Santos, Orlando Garcia Ribeiro, Marcelo De Franco, Wafa Hanna Koury Cabrera, Marcelo Yudi Icimoto, Nancy Starobinas, Geraldo Magalhães, Leticia Figueiredo Monteleone, Silas Fernandes Eto, Carlos DeOcesano-Pereira, Mauricio Barbugiani Goldfeder, Kerly Fernanda Mesquita Pasqualoto, Tommaso A. Dragani, Olga Célia Martinez Ibañez
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
We identified Pycard and BC017158 genes as putative effectors of the Quantitative Trait locus (QTL) that we mapped at distal chromosome 7 named Irm1 for Inflammatory response modulator 1, controlling acute inflammatory response (AIR) and the producti
Externí odkaz:
https://doaj.org/article/5e7186b6f49446299b8750ef1b7beca8
Autor:
Priscila Hess Lopes, Mário T. Murakami, Fernanda C. V. Portaro, Kerly Fernanda Mesquita Pasqualoto, Carmen van den Berg, Denise V. Tambourgi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 310-321 (2019)
Loxosceles spiders’ venoms consist of a mixture of proteins, including the sphingomyelinases D (SMases D), which are the main toxic components responsible for local and systemic effects in human envenomation. Herein, based on the structural informa
Externí odkaz:
https://doaj.org/article/71a641201d154ec4a2292fbac0c96f28
Autor:
Nancy Oguiura, Poliana Garcia Corrêa, Isabella Lemos Rosmino, Ana Olívia de Souza, Kerly Fernanda Mesquita Pasqualoto
Publikováno v:
Toxins, Vol 14, Iss 1, p 1 (2021)
β-defensins are antimicrobial peptides presenting in vertebrate animals. They participate in innate immunity, but little is known about them in reptiles, including snakes. Although several β-defensin genes were described in Brazilian snakes, their
Externí odkaz:
https://doaj.org/article/dcbced85275245b9bf4cc1f392a9c0a4
Autor:
Bárbara Athayde Vaz Galvão da Silva, Ana Marisa Chudzinski-Tavassi, Kerly Fernanda Mesquita Pasqualoto
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Background: The identification of fragment sequences, or motifs, within a therapeutic protein that may elicit an immune response when processed by T-cells can be provided by computer-aided approaches. Immunogenicity is a significant problem associate
Externí odkaz:
https://doaj.org/article/1437a22d64ae4fb6b82b85df2c088c03
Autor:
Ana Claudia Sato, Rosemary Viola Bosch, Sonia Elisabete Alves Will, Miryam Paola Alvarez-Flores, Mauricio Barbugiani Goldfeder, Kerly Fernanda Mesquita Pasqualoto, Bárbara Athayde Vaz Galvão da Silva, Sonia Aparecida de Andrade, Ana Marisa Chudzinski-Tavassi
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 22, Iss 0 (2017)
Abstract Background Hemolin proteins are cell adhesion molecules from lepidopterans involved in a wide range of cell interactions concerning their adhesion properties. However, hemolin’s roles in cell proliferation and wound healing are not fully e
Externí odkaz:
https://doaj.org/article/52aadd58a2ff40aba4cbf183f724eb06
Autor:
Sibila Roberta Marques Grallert, Carlota de Oliveira Rangel-Yagui, Kerly Fernanda Mesquita Pasqualoto, Leoberto Costa Tavares
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 48, Iss 1, Pp 1-16 (2012)
Micelles composed of amphiphilic copolymers linked to a radioactive element are used in nuclear medicine predominantly as a diagnostic application. A relevant advantage of polymeric micelles in aqueous solution is their resulting particle size, which
Externí odkaz:
https://doaj.org/article/e9665508e633408681eead446486d653
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 46, Iss 4, Pp 741-751 (2010)
Drugs acting on the central nervous system (CNS) have to cross the blood-brain barrier (BBB) in order to perform their pharmacological actions. Passive BBB diffusion can be partially expressed by the blood/brain partition coefficient (logBB). As the
Externí odkaz:
https://doaj.org/article/131b261ea5be43d0a0cb17e5cff5cfad
Autor:
Daniela Gonçalves Rando, Jeanine Giarolla, Kerly Fernanda Mesquita Pasqualoto, Elizabeth Igne Ferreira
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 46, Iss 2, Pp 311-321 (2010)
Leishmaniasis is an important health and social problem for which there is limited effective therapy. Chalcones and N-acylhydrazones have been studied as promising antileishmanial agents in enzymatic inhibition and in vitro assays. Since these chemic
Externí odkaz:
https://doaj.org/article/3fb8253431b74cf2a11677751e39f4cb
Autor:
Mariana Celestina Frojuello Costa Bernstorff Damião, Kerly Fernanda Mesquita Pasqualoto, Michelle Carneiro Polli, Roberto Parise Filho
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 4 (2014)
Purpose. Prodrug design is a strategy that can be used to adjust physicochemical properties of drugs in order to overcome pharmacokinetic problems, such as poor oral bioavailability. However, Lipinski´s and Veber´s rules predict whether compounds w
Externí odkaz:
https://doaj.org/article/0dc89c540a394bfaa13d22305cbabbf3