Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Keri Martinowich"'
Autor:
Nicholas J. Eagles, Svitlana V. Bach, Madhavi Tippani, Prashanthi Ravichandran, Yufeng Du, Ryan A. Miller, Thomas M. Hyde, Stephanie C. Page, Keri Martinowich, Leonardo Collado-Torres
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Visium is a widely-used spatially-resolved transcriptomics assay available from 10x Genomics. Standard Visium capture areas (6.5mm by 6.5mm) limit the survey of larger tissue structures, but combining overlapping images and associ
Externí odkaz:
https://doaj.org/article/d272854e1cd44ad7b58bc18c2d6c72ba
Autor:
Lionel A. Rodriguez, Matthew Nguyen Tran, Renee Garcia-Flores, Seyun Oh, Robert A. Phillips, Elizabeth A. Pattie, Heena R. Divecha, Sun Hong Kim, Joo Heon Shin, Yong Kyu Lee, Carly Montoya, Andrew E. Jaffe, Leonardo Collado-Torres, Stephanie C. Page, Keri Martinowich
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The lateral septum (LS), a GABAergic structure located in the basal forebrain, is implicated in social behavior, learning, and memory. We previously demonstrated that expression of tropomyosin kinase receptor B (TrkB) in LS neurons is requir
Externí odkaz:
https://doaj.org/article/8b1c03c8b1cb416194de52904abaf057
Autor:
Lukas M Weber, Heena R Divecha, Matthew N Tran, Sang Ho Kwon, Abby Spangler, Kelsey D Montgomery, Madhavi Tippani, Rahul Bharadwaj, Joel E Kleinman, Stephanie C Page, Thomas M Hyde, Leonardo Collado-Torres, Kristen R Maynard, Keri Martinowich, Stephanie C Hicks
Publikováno v:
eLife, Vol 12 (2024)
Norepinephrine (NE) neurons in the locus coeruleus (LC) make long-range projections throughout the central nervous system, playing critical roles in arousal and mood, as well as various components of cognition including attention, learning, and memor
Externí odkaz:
https://doaj.org/article/5535bef8bfda4d938789135e8f5f9d86
Autor:
Madhavi Tippani, Elizabeth A. Pattie, Brittany A. Davis, Claudia V. Nguyen, Yanhong Wang, Srinidhi Rao Sripathy, Brady J. Maher, Keri Martinowich, Andrew E. Jaffe, Stephanie Cerceo Page
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Calcium imaging is a powerful technique for recording cellular activity across large populations of neurons. However, analysis methods capable of single-cell resolution in cultured neurons, especially for cultures derived from hum
Externí odkaz:
https://doaj.org/article/eb56475a8b4b4772b6ccf8c3a8d880ff
Autor:
Brenda Pardo, Abby Spangler, Lukas M. Weber, Stephanie C. Page, Stephanie C. Hicks, Andrew E. Jaffe, Keri Martinowich, Kristen R. Maynard, Leonardo Collado-Torres
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-5 (2022)
Abstract Background Spatially-resolved transcriptomics has now enabled the quantification of high-throughput and transcriptome-wide gene expression in intact tissue while also retaining the spatial coordinates. Incorporating the precise spatial mappi
Externí odkaz:
https://doaj.org/article/fd7c7cc7b496491490ee36657df60094
Autor:
Anthony D. Ramnauth, Kristen R. Maynard, Alisha S. Kardian, BaDoi N. Phan, Madhavi Tippani, Sumita Rajpurohit, John W. Hobbs, Stephanie Cerceo Page, Andrew E. Jaffe, Keri Martinowich
Publikováno v:
Brain Stimulation, Vol 15, Iss 2, Pp 427-433 (2022)
Background: Electroconvulsive therapy (ECT) efficacy is hypothesized to depend on induction of molecular and cellular events that trigger neuronal plasticity. Investigating how electroconvulsive seizures (ECS) impact plasticity in animal models can h
Externí odkaz:
https://doaj.org/article/14f862501964433caa632d20a3251f9d
Autor:
Madhavi Tippani, Heena R. Divecha, Joseph L. Catallini, Sang H. Kwon, Lukas M. Weber, Abby Spangler, Andrew E. Jaffe, Thomas M. Hyde, Joel E. Kleinman, Stephanie C. Hicks, Keri Martinowich, Leonardo Collado-Torres, Stephanie C. Page, Kristen R. Maynard
Publikováno v:
Biological Imaging, Vol 3 (2023)
Spatially resolved transcriptomics (SRT) is a growing field that links gene expression to anatomical context. SRT approaches that use next-generation sequencing (NGS) combine RNA sequencing with histological or fluorescent imaging to generate spatial
Externí odkaz:
https://doaj.org/article/7340b1102c004b1bb09838cdf6156fe8
Autor:
Chaichontat Sriworarat, Annie Nguyen, Nicholas J. Eagles, Leonardo Collado-Torres, Keri Martinowich, Kristen R. Maynard, Stephanie C. Hicks
Publikováno v:
Biological Imaging, Vol 3 (2023)
High-resolution and multiplexed imaging techniques are giving us an increasingly detailed observation of a biological system. However, sharing, exploring, and customizing the visualization of large multidimensional images can be a challenge. Here, we
Externí odkaz:
https://doaj.org/article/eae8bdc7fb7b49d9b405ab84a0327b5c
Autor:
Emily E. Burke, Joshua G. Chenoweth, Joo Heon Shin, Leonardo Collado-Torres, Suel-Kee Kim, Nicola Micali, Yanhong Wang, Carlo Colantuoni, Richard E. Straub, Daniel J. Hoeppner, Huei-Ying Chen, Alana Sellers, Kamel Shibbani, Gregory R. Hamersky, Marcelo Diaz Bustamante, BaDoi N. Phan, William S. Ulrich, Cristian Valencia, Amritha Jaishankar, Amanda J. Price, Anandita Rajpurohit, Stephen A. Semick, Roland W. Bürli, James C. Barrow, Daniel J. Hiler, Stephanie C. Page, Keri Martinowich, Thomas M. Hyde, Joel E. Kleinman, Karen F. Berman, Jose A. Apud, Alan J. Cross, Nicholas J. Brandon, Daniel R. Weinberger, Brady J. Maher, Ronald D. G. McKay, Andrew E. Jaffe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here, authors present results of a hiPSC transcriptomics study on corticogenesis from multiple donors across four transitions in differentiation. They present a bulk data deconvolution method and show that co-culturing human NPCs with rodent astrocyt
Externí odkaz:
https://doaj.org/article/a91415f76f3b4ff6b00a1fb9ef500aaf
Autor:
Kristen R Maynard, John W Hobbs, BaDoi N Phan, Amolika Gupta, Sumita Rajpurohit, Courtney Williams, Anandita Rajpurohit, Joo Heon Shin, Andrew E Jaffe, Keri Martinowich
Publikováno v:
eLife, Vol 7 (2018)
Brain-derived neurotrophic factor (Bdnf) transcription is controlled by several promoters, which drive expression of multiple transcripts encoding an identical protein. We previously reported that BDNF derived from promoters I and II is highly expres
Externí odkaz:
https://doaj.org/article/b1d6fa50a0c8472ea9b05893233fd755