Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Keri M. Tate"'
Autor:
Gernot Neumayer, Jessica L. Torkelson, Shengdi Li, Kelly McCarthy, Hanson H. Zhen, Madhuri Vangipuram, Marius M. Mader, Gulilat Gebeyehu, Taysir M. Jaouni, Joanna Jacków-Malinowska, Avina Rami, Corey Hansen, Zongyou Guo, Sadhana Gaddam, Keri M. Tate, Alberto Pappalardo, Lingjie Li, Grace M. Chow, Kevin R. Roy, Thuylinh Michelle Nguyen, Koji Tanabe, Patrick S. McGrath, Amber Cramer, Anna Bruckner, Ganna Bilousova, Dennis Roop, Jean Y. Tang, Angela Christiano, Lars M. Steinmetz, Marius Wernig, Anthony E. Oro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract We present Dystrophic Epidermolysis Bullosa Cell Therapy (DEBCT), a scalable platform producing autologous organotypic iPS cell-derived induced skin composite (iSC) grafts for definitive treatment. Clinical-grade manufacturing integrates CRI
Externí odkaz:
https://doaj.org/article/beaa5273b9ae4861a2bf161a05a28b1a
Autor:
Glynis McCray, Billie J. Marks, Brain M. Fendly, Richard M. Lawn, Cornelia M. Gorman, Keri M. Tate, Lisa R. Paborsky, Gordon A. Vehar, Karen L. Fisher
Publikováno v:
Protein engineering. 3(6)
We describe a mammalian cell expression system used to rapidly produce microgram quantities of a membrane protein used as an immunogen. A fusion protein expression vector was constructed which contained the signal sequence and 27 amino acids of the H
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
The significance of the cleavage at arginine-275 of human t-PA has been the subject of debate. It has been reported, as expected for a member of the serine protease family, that the single chain form is a zymogen and that generation of catalytic acti
Autor:
Herbert L. Heyneker, Gordon A. Vehar, Marjorie E. Winkler, Keri M. Tate, Deborah L. Higgins, William E. Holmes
Publikováno v:
Biochemistry. 26(2)
Activation of the zymogen form of a serine protease is associated with a conformational change that follows proteolysis at a specific site. Tissue-type plasminogen activator (t-PA) is homologous to mammalian serine proteases and contains an apparent