Zobrazeno 1 - 10 of 84 pro vyhledávání: '"Keri Janesko‐Feldman"'
1
Akademický článek
Endogenous Interleukin-17a Contributes to Normal Spatial Memory Retention but Does Not Affect Early Behavioral or Neuropathological Outcomes after Experimental Traumatic Brain Injury
Autor: Dennis W. Simon, Itay Raphael, Kendall M. Johnson, C. Edward Dixon, Vincent Vagni, Keri Janesko-Feldman, Patrick M. Kochanek, H?lya Bayir, Robert S.B. Clark, Mandy J. McGeachy
Publikováno v: Neurotrauma Reports, Vol 3, Iss 1, Pp 340-351 (2022)
Interleukin-17 (IL-17) is a proinflammatory cytokine primarily secreted in the brain by inflammatory T lymphocytes and glial cells. IL-17+ T-helper (Th17) cells are increased in the ipsilateral hemisphere after experimental traumatic brain injury (TB
Externí odkaz: https://doaj.org/article/9df196680da748bd88313faa71ecf773
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2
Akademický článek
PHLPP Inhibitor NSC74429 Is Neuroprotective in Rodent Models of Cardiac Arrest and Traumatic Brain Injury
Autor: Travis C. Jackson, Cameron Dezfulian, Vincent A. Vagni, Jason Stezoski, Keri Janesko-Feldman, Patrick M. Kochanek
Publikováno v: Biomolecules, Vol 12, Iss 10, p 1352 (2022)
Pleckstrin homology domain and leucine rich repeat protein phosphatase (PHLPP) knockout mice have improved outcomes after a stroke, traumatic brain injury (TBI), and decreased maladaptive vascular remodeling following vascular injury. Thus, small-mol
Externí odkaz: https://doaj.org/article/94f79b484c8b480abdbdce6149230bfd
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3
Akademický článek
Cardiac Arrest Induced by Asphyxia Versus Ventricular Fibrillation Elicits Comparable Early Changes in Cytokine Levels in the Rat Brain, Heart, and Serum
Autor: Thomas Uray, Cameron Dezfulian, Abigail A. Palmer, Kristin M. Miner, Rehana K. Leak, Jason P. Stezoski, Keri Janesko‐Feldman, Patrick M. Kochanek, Tomas Drabek
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Current postresuscitative care after cardiac arrest (CA) does not address the cause of CA. We previously reported that asphyxial CA (ACA) and ventricular fibrillation CA (VFCA) elicit unique injury signatures. We hypothesized that the earl
Externí odkaz: https://doaj.org/article/d62d95d93cc243bfa7def83aa2a0f282
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4
Akademický článek
Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice
Autor: Travis C. Jackson, C. Edward Dixon, Keri Janesko-Feldman, Vincent Vagni, Shawn E. Kotermanski, Edwin K. Jackson, Patrick M. Kochanek
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Suprachiasmatic nucleus circadian oscillatory protein (SCOP) (a.k.a. PHLPP1) regulates long-term memory consolidation in the brain. Using a mouse model of controlled cortical impact (CCI) we tested if (1) brain tissue levels of SCOP/PHLPP1 i
Externí odkaz: https://doaj.org/article/5d728bdcc90544d2bf5dd7ed47464977
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