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Autor:
Maureen Tarsio, Michael W. Schmidtke, Pablo Lazcano, Patricia M. Kane, Michael Salsaa, Miriam L. Greenberg, Christian A. Reynolds, Kerestin Aziz, Maik Hüttemann
Publikováno v:
The Journal of biological chemistry. 297(4)
Valproate (VPA) is a widely used mood stabilizer, but its therapeutic mechanism of action is not understood. This knowledge gap hinders the development of more effective drugs with fewer side effects. Using the yeast model to elucidate the effects of