Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Keren Nebenzahl"'
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005420 (2016)
The DNA damage response (DDR) is a conglomerate of pathways designed to detect DNA damage and signal its presence to cell cycle checkpoints and to the repair machinery, allowing the cell to pause and mend the damage, or if the damage is too severe, t
Externí odkaz:
https://doaj.org/article/4dcf6eda7e30459a8ae35fef5754fb9c
Objective In a previous study, we demonstrated that perinatal hypoxia leads to premature activation and initiation of growth in dormant follicles, leading to diminished ovarian reserve. Other reports have also established a connection between intraut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68607d3a8e58bdc7509e47234f2ca8ac
https://doi.org/10.21203/rs.3.rs-2801535/v1
https://doi.org/10.21203/rs.3.rs-2801535/v1
Perinatal hypoxia leads to primordial follicle activation and premature depletion of ovarian reserve
Autor:
Ofer Fainaru, Zeev Weiner, Ola Gutzeit, Ron Beloosesky, Yuval Ginsberg, Roee Iluz, Keren Nebenzahl
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 35:7844-7848
The human ovary contains 6-million follicles during the 20th week of embryonic development and 1 million at birth. Girls born at small for gestational age weight demonstrate higher FSH levels during infancy, an earlier onset of puberty, and menarche.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f557eff363eeee518ae4c85a93ad8846
https://doi.org/10.1080/14767058.2021.1937985
https://doi.org/10.1080/14767058.2021.1937985
Autor:
Hanan Khoury-Haddad, Keren Nebenzahl-Sharon, Hassan Shalata, Tamar Kleinberger, Nabieh Ayoub, Rakefet Sharf, Sook-Young Sohn, Patrick Hearing, Jana Amer
Publikováno v:
Journal of Virology. 93
The adenovirus (Ad) E4orf4 protein was reported to contribute to inhibition of ATM- and ATR-regulated DNA damage signaling during Ad infection and following treatment with DNA-damaging drugs. Inhibition of these pathways improved Ad replication, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f002242273c64a071ecc1356c327d0b
https://doi.org/10.1128/jvi.02253-18
https://doi.org/10.1128/jvi.02253-18
Autor:
Jana Amer, Keren Nebenzahl-Sharon, Hanan Khoury-Haddad, Patrick Hearing, Rakefet Sharf, Nabieh Ayoub, Tamar Kleinberger, Hassan Shalata, Sook-Young Sohn
Publikováno v:
Journal of Virology. 93
The adenovirus (Ad) E4orf4 protein contributes to virus-induced inhibition of the DNA damage response (DDR) by reducing ATM and ATR signaling. Consequently, E4orf4 inhibits DNA repair and sensitizes transformed cells to killing by DNA-damaging drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011d94ac8e9ae4f7beead10fa2c9634f
https://doi.org/10.1128/jvi.01365-18
https://doi.org/10.1128/jvi.01365-18