Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Keren Bahar‐Shany"'
Autor:
Eva Hulstaert, Keren Levanon, Annelien Morlion, Stefan Van Aelst, Anthony-Alexander Christidis, Ruben Zamar, Jasper Anckaert, Kimberly Verniers, Keren Bahar-Shany, Stav Sapoznik, Jo Vandesompele, Pieter Mestdagh
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 155-164 (2022)
Background: Most ovarian cancer patients are diagnosed at an advanced stage and have a high mortality rate. Current screening strategies fail to improve prognosis because markers that are sensitive for early stage disease are lacking. This medical ne
Externí odkaz:
https://doaj.org/article/1167a7ed4eff480293361fff2bcb29f0
Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis
Autor:
Stav Sapoznik, Keren Bahar-Shany, Hadar Brand, Yishay Pinto, Orshay Gabay, Efrat Glick-Saar, Chen Dor, Oranit Zadok, Iris Barshack, Adi Zundelevich, Einav Nili Gal-Yam, Yuval Yung, Ariel Hourvitz, Jacob Korach, Mario Beiner, Jasmine Jacob, Erez Y. Levanon, Michal Barak, Sarit Aviel-Ronen, Keren Levanon
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 2, Pp 90-99 (2016)
In recent years, the notion that ovarian carcinoma results from ovulation-induced inflammation of the fallopian tube epithelial cells (FTECs) has gained evidence. However, the mechanistic pathway for this process has not been revealed yet. In the cur
Externí odkaz:
https://doaj.org/article/50d32a92be1b41c78b0e4e4cd7cd869a
Autor:
Keren Bahar‐Shany, Georgina D. Barnabas, Lisa Deutsch, Netanel Deutsch, Efrat Glick‐Saar, Dan Dominissini, Stav Sapoznik, Limor Helpman, Tamar Perri, Anna Blecher, Guy Katz, Itai Yagel, Orgad Rosenblatt, Daniel Shai, Benny Brandt, Raanan Meyer, Aya Mohr‐Sasson, Alexander Volodarsky‐Perel, Itamar Zilberman, Shunit Armon, Ariella Jakobson‐Setton, Ram Eitan, Yfat Kadan, Mario Beiner, Dana Josephy, Malka Brodsky, Eitan Friedman, Liat Anafi, Yossef Molchanov, Jacob Korach, Tamar Geiger, Keren Levanon
Publikováno v:
International journal of cancerREFERENCES. 152(4)
No current screening methods for high-grade ovarian cancer (HGOC) guarantee effective early detection for high-risk women such as germline BRCA mutation carriers. Therefore, the standard-of-care remains risk-reducing salpingo-oophorectomy (RRSO) arou
Autor:
Moshit Lindzen, Diana Drago, Dan Aderka, Yosef Yarden, Keren Levanon, Nishanth Belugali Nataraj, Belinda Sánchez Ramírez, Soma Ghosh, Silvia Carvalho, Orith Leitner, Maik Dahlhoff, Iain A. McNeish, Einav Zmora, Keren Bahar Shany, Ashish Noronha, Stav Sapoznik
Publikováno v:
Oncogene
Ovarian cancer (OvCA) remains one of the most devastating malignancies, but treatment options are still limited. We report that amphiregulin (AREG) can serve as an effective and safe pharmacological target in a syngeneic murine model. AREG is highly
Autor:
Hadar Brand, Keren Bahar-Shany, Tamar Geiger, Yair Pozniak, Jasmine Jacob-Hirsch, Keren Levanon, Yuval Yung, Georgina D. Barnabas, Stav Sapoznik, Ariel Hourvitz
Publikováno v:
Carcinogenesis. 41:1703-1712
The fallopian tube secretory epithelial cells (FTSECs) are the cell-of-origin of most high-grade serous ovarian carcinomas (HGSOC). FTSECs are repeatedly exposed to inflammation induced by follicular fluid (FF) that is released with every ovulation c
Autor:
David Stockheim, Eitan Friedman, Ariella Jakobson-Setton, Tamar Perri, Oranit Zadok, Jacob Korach, Nissim Arbib, Sarit Aviel-Ronen, Shunit Armon, Keren Bahar-Shany, Tamar Geiger, Keren Levanon, Limor Helpman, Yfat Kadan, Mario E. Beiner, Michal Harel, Hadar Brand, Ram Eitan, Anna Blecher, Georgina D. Barnabas, Stav Sapoznik, Guy Katz, Omer Weitzner, Benny Brandt
Publikováno v:
Mol Cell Proteomics
High-grade ovarian cancer (HGOC) is the leading cause of mortality from gynecological malignancies, because of diagnosis at a metastatic stage. Current screening options fail to improve mortality because of the absence of early-stage-specific biomark
Autor:
Adina Weinberger, Ron Shaoul, Morgan G. I. Langille, Alexandria P. Cogdill, Giuseppe Mallel, Talia Golan, Anat Ronai, Arnon Meltser, Vancheswaran Gopalakrishnan, Christian U. Blank, Jennifer A. Wargo, Einav Yehuda-Shnaidman, Tali Dadosh, Maya Dadiani, Daniel S. Peeper, Merav Rokah, Alon Ben-Nun, Reetakshi Arora, Elinor Gigi, Aviram Nissan, Keren Levanon, Zachary A. Cooper, Tatiana Dorfman, Gavin M. Douglas, Iris Kamer, Gabriel Ologun, Ilana Livyatan, Zvi R. Cohen, Iris Barshack, Noam Shental, Elisa A. Rozeman, Nicola Baldini, Einav Nili Gal-Yam, Nancy Gavert, Shlomit Yust-Katz, Ran Kremer, Eran Segal, Ravid Straussman, Roi Weiser, Yaara Zwang, Yuval Bussi, Hagit Shapira, Tehila Atlan, Dan J. Raz, Amnon Amit, Smadar Levin-Zaidman, Bella Kaufman, Aviva Rotter-Maskowitz, Keren Bahar-Shany, Tali Siegal, Abdul Wadud Khan, Judith Sandbank, Deborah Nejman, Gili Perry, Jair Bar, Maya Lotan-Pompan, Sofia Avnet, Ofra Golani, Garold Fuks, Leore T. Geller, Sagi Harnof
Publikováno v:
Science
Profiling tumor bacteria Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear. As an initial step toward addressing this question, Nejman et al. pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c3a1966e5196491836aaf3aaf203f3
http://hdl.handle.net/11585/780581
http://hdl.handle.net/11585/780581
Publikováno v:
Oncotarget
// Stav Sapoznik 1, * , Sarit Aviel-Ronen 2, 3, 4, * , Keren Bahar-Shany 1 , Oranit Zadok 2 and Keren Levanon 1, 3, 4 1 Sheba Cancer Research Center, Chaim Sheba Medical Center, Ramat Gan 52621, Israel 2 Department of Pathology, Chaim Sheba Medical C
Autor:
Helit Cohen, Chaim Wachtel, Keren Bahar-Shany, Sol Efroni, Sarit Aviel-Ronen, Danny Barash, Alona Zilberberg, Iris Barshack, Rotem Ben-Hamo, Jacob Korach, Keren Levanon
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 3, Iss 1, Pp 1-11 (2019)
npj Precision Oncology, Vol 3, Iss 1, Pp 1-11 (2019)
Paclitaxel, the most commonly used form of chemotherapy, is utilized in curative protocols in different types of cancer. The response to treatment differs among patients. Biological interpretation of a mechanism to explain this personalized response
Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis
Autor:
Orshay Gabay, Stav Sapoznik, Oranit Zadok, Jasmine Jacob, Keren Bahar-Shany, Adi Zundelevich, Yuval Yung, Hadar Brand, Iris Barshack, Jacob Korach, Sarit Aviel-Ronen, Michal Barak, Efrat Glick-Saar, Ariel Hourvitz, Mario E. Beiner, Keren Levanon, Chen Dor, Einav Nili Gal-Yam, Erez Y. Levanon, Yishay Pinto
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 2, Pp 90-99 (2016)
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 2, Pp 90-99 (2016)
In recent years, the notion that ovarian carcinoma results from ovulation-induced inflammation of the fallopian tube epithelial cells (FTECs) has gained evidence. However, the mechanistic pathway for this process has not been revealed yet. In the cur