Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Keratinocytes/pathology"'
Autor:
Guy Serre, Marie Reynier, Alain Moga, Corinne Leprince, Sophie Allart, Dominique Goudounèche, Michel Simon
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩
Journal of Investigative Dermatology, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩
Journal of Investigative Dermatology, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩
International audience; Myosin Vb (Myo5b) is an unconventional myosin involved in the actin-dependent transport and tethering of intracellular organelles. In the epidermis, granular keratinocytes accumulate cytoplasmic lamellar bodies (LBs), secretor
Autor:
Christine Pich, Asma Smahi, Daniel Hohl, Elena Chiticariu, Hyun-Sook Park, Gabriela Blanchard, Marcel Huber, Markus Plomann, Fanny Morice-Picard, Eirini Papanastasi, Pierre Vabres, Daniel Bachmann
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications biology, vol. 4, no. 1, pp. 544
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications biology, vol. 4, no. 1, pp. 544
Actin-Related Protein-Testis1 (ARP-T1)/ACTRT1 gene mutations cause the Bazex-Dupré-Christol Syndrome (BDCS) characterized by follicular atrophoderma, hypotrichosis, and basal cell cancer. Here, we report an ARP-T1 interactome (PXD016557) that includ
Autor:
Deepa Mohanan, Stephan Nobbe, Lars E. French, Caroline Ospelt, Mark Mellett, Emmanuel Contassot, Barbara Meier, Phil F. Cheng, Margot Thome, Betina Kiefer, Rebekka Schairer, Takashi K. Satoh
Publikováno v:
The Journal of investigative dermatology, vol. 138, no. 9, pp. 2010-2023
Rare autosomal dominant mutations in the gene encoding the keratinocyte signaling molecule CARD14, have been associated with an increased susceptibility to psoriasis, but the physiological impact of CARD14 gain-of-function mutations remains to be ful
Autor:
Mindy Tsai, Nicolas Gaudenzio, Axel Roers, See-Ying Tam, Yuko Kawakami, Pierre Chambon, Philipp Starkl, Dimitri Pirottin, Stephen J. Galli, Sophie El Abbas, Jinah Kim, Nadine Antoine, Fabrice Bureau, Oliwia W Zurek, Laurent L. Reber, Toshiaki Kawakami, Thomas Marichal, Riccardo Sibilano
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩
Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩
International audience; Epidermal keratinocytes form a structural and immune barrier that is essential for skin homeostasis. However, the mechanisms that regulate epidermal barrier function are incompletely understood. Here we have found that keratin
Autor:
Valérie Pendaries, Nicolas Lecland, Cécile Viodé, Andreas Merdes, Christiane Bierkamp, Carle Paul, Daniel Redoules, Michel Simon, Chiung-Yueh Hsu
Publikováno v:
Journal of Dermatological Science
Journal of Dermatological Science, Elsevier, 2018, 91 (1), pp.87-96. ⟨10.1016/j.jdermsci.2018.04.008⟩
Journal of Dermatological Science, Elsevier, 2018, 91 (1), pp.87-96. ⟨10.1016/j.jdermsci.2018.04.008⟩
International audience; Background: A variety of human skin disorders is characterized by defects in the epidermal barrier, leading to dehydration, itchiness, and rashes. Previously published literature suggests that microtubule stabilization at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa64eca8fb532dba841126c6c2063946
https://hal.archives-ouvertes.fr/hal-02323387
https://hal.archives-ouvertes.fr/hal-02323387
Autor:
Seung-Hee Jo, Renato G. Panizzon, Paola Ostano, Dania Al Labban, G. Paolo Dotto, Massimo Bongiovanni, Chiara Saglietti
Publikováno v:
The Journal of clinical investigation, vol. 128, no. 6, pp. 2581-2599
Notch 1/2 genes play tumor-suppressing functions in squamous cell carcinoma (SCC), a very common malignancy in skin and internal organs. In contrast with Notch, we show that the transcription factor CSL (also known as RBP-Jκ), a key effector of cano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28345da224ab25046bd6de3b630f1fe
https://serval.unil.ch/notice/serval:BIB_64DFBBAE75C2
https://serval.unil.ch/notice/serval:BIB_64DFBBAE75C2
Autor:
Jacob P. Thyssen, Jeanne D. Johansen, Niels H. H. Heegaard, Sanja Kezic, Christoph Riethmüller, Allan Linneberg, Berit C. Carlsen, K.A. Engebretsen, Josefine Bandier
Publikováno v:
Journal of the European Academy of Dermatology and Venereology, 32(5), 796-804. Wiley-Blackwell
Engebretsen, K A, Bandier, J, Kezic, S, Riethmüller, C, Heegaard, N H H, Carlsen, B C, Linneberg, A, Johansen, J D & Thyssen, J P 2018, ' Concentration of filaggrin monomers, its metabolites and corneocyte surface texture in individuals with a history of atopic dermatitis and controls ', Journal of the European Academy of Dermatology and Venereology, vol. 32, no. 5, pp. 796-804 . https://doi.org/10.1111/jdv.14801
Engebretsen, K A, Bandier, J, Kezic, S, Riethmüller, C, Heegaard, N H H, Carlsen, B C, Linneberg, A, Johansen, J D & Thyssen, J P 2018, ' Concentration of filaggrin monomers, its metabolites and corneocyte surface texture in individuals with a history of atopic dermatitis and controls ', Journal of the European Academy of Dermatology and Venereology, vol. 32, no. 5, pp. 796-804 . https://doi.org/10.1111/jdv.14801
Background: Atopic dermatitis (AD) is characterized by skin barrier dysfunction. Notably, a high number of nano-scale protrusions on the surface of corneocytes, which can be expressed by the Dermal Texture Index (DTI), were recently associated with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7ba8bedbfcae24bed7cde9ce689c95
https://pure.amc.nl/en/publications/concentration-of-filaggrin-monomers-its-metabolites-and-corneocyte-surface-texture-in-individuals-with-a-history-of-atopic-dermatitis-and-controls(f8246e06-754e-4676-9330-b777a13bebf9).html
https://pure.amc.nl/en/publications/concentration-of-filaggrin-monomers-its-metabolites-and-corneocyte-surface-texture-in-individuals-with-a-history-of-atopic-dermatitis-and-controls(f8246e06-754e-4676-9330-b777a13bebf9).html
Autor:
Ludivine Houel-Renault, Fatima Bouali, Sébastien Martien, Christian Slomianny, Chantal Vercamer, Corinne Abbadie, Karo Gosselin, Emeric Deruy, Yvan de Launoit, Fazia Chelli, Thibault Dujardin
Publikováno v:
American Journal of Pathology
American Journal of Pathology, American Society for Investigative Pathology, 2009, 174 (2), pp.423-35. ⟨10.2353/ajpath.2009.080332⟩
American Journal of Pathology, American Society for Investigative Pathology, 2009, 174 (2), pp.423-35. ⟨10.2353/ajpath.2009.080332⟩
International audience; Normal cells reach senescence after a specific time and number of divisions, leading ultimately to cell death. Although escape from this fate may be a requisite step in neoplastic transformation, the mechanisms governing senes
Publikováno v:
The American Journal of Dermatopathology, Vol. 17, No 2 (1995) pp. 139-144
In this paper, we describe the immunophenotype and ultrastructure of a new macrophage subpopulation present in inflamed but not in normal human skin. In biopsy material from patients with psoriasis (n = 4), atopic dermatitis (n = 4), and positive pat
Autor:
Wolfram Hoetzenecker, Paola Ostano, Günther F.L. Hofbauer, Reinhard Dummer, Alexandre Reymond, Bing Hu, Einar Castillo, Wassim Raffoul, G. Paolo Dotto, Louise Harewood
Publikováno v:
CELL
Cell, vol. 149, no. 6, pp. 1207-1220
Cell, vol. 149, no. 6, pp. 1207-1220
It is currently unclear whether tissue changes surrounding multifocal epithelial tumors are a cause or consequence of cancer. Here, we provide evidence that loss of mesenchymal Notch/CSL signaling causes tissue alterations, including stromal atrophy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cbba120394bacd20775f818e295b81
https://europepmc.org/articles/PMC3578441/
https://europepmc.org/articles/PMC3578441/