Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kepeng Ou"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 1984-1990 (2024)
Somatostatin, a naturally produced neuroprotective peptide, depresses excitatory neurotransmission and exerts anti-proliferative and anti-inflammatory effects on the retina. In this review, we summarize the progress of somatostatin treatment of diabe
Externí odkaz:
https://doaj.org/article/235aacb7284d466399f9bef2e58d4970
Autor:
Lanyue Zhang, Youjian Li, Zhengyu Wu, Qiang Shen, Chunqin Zeng, Han Liu, Xuedong Zhang, Jiaxing Yang, Qiaoling Liu, Dianyong Tang, Kepeng Ou, Yanhong Fang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveChoroidal neovascularization (CNV) represents the predominant form of advanced wet Age-related Macular Degeneration (wAMD). Macrophages play a pivotal role in the pathological progression of CNV. Meteorin-like (Metrnl), a novel cytokine know
Externí odkaz:
https://doaj.org/article/8d89f38d95a5447393011c488c6af147
Autor:
Youjian Li, Mengjie Wang, Xun Li, Jiehong Jia, Fei Pan, Wen Li, Zhongzhu Chen, Dianyong Tang, Kepeng Ou
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 8, p 283 (2024)
Background: Humankind have been struggling with colorectal cancer (CRC) for long period with its rapid progression and invasive metastasis. By hyperactivating IL-6/STAT3 signaling, CRC facilitates the capacity of angiogenesis to plunder massive nutri
Externí odkaz:
https://doaj.org/article/096a6249ac354852a775edc8d7c1a7e9
Autor:
Zheng Huang, Tong Xian, Xiangyi Meng, Huaisong Hu, Lixia Gao, Jiuhong Huang, Donglin Yang, Kepeng Ou, Bochu Wang, Yimei Zhang
Publikováno v:
Molecules, Vol 28, Iss 19, p 6972 (2023)
Photodynamic therapy (PDT) is an effective noninvasive therapeutic strategy that has been widely used for anti-tumor therapy by the generation of excessive highly cytotoxic ROS. However, the poor water solubility of the photosensitizer, reactive oxyg
Externí odkaz:
https://doaj.org/article/e35db13c27874f35951d14334e30587f
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1919-1928 (2022)
Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and other retinal neurons, which are caused by a group of retinal diseases affecting various age groups, and increasingly prevalent in
Externí odkaz:
https://doaj.org/article/c339a1aebb784a10bf3c7fff71b73381
Autor:
Junxiao Ren, Weihua Tian, Keren Jiang, Zhang Wang, Dandan Wang, Zhuanjian Li, Fengbin Yan, Yanbin Wang, Yadong Tian, Kepeng Ou, Hongjun Wang, Xiangtao Kang, Hong Li, Xiaojun Liu
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Estrogen plays an essential role in female development and reproductive function. In chickens, estrogen is critical for lipid metabolism in the liver. The regulatory molecular network of estrogen in chicken liver is poorly underst
Externí odkaz:
https://doaj.org/article/7f56e3ac64f04c85ac6f8cd10d4781d8
Autor:
Kepeng Ou, Sonja Mertsch, Sofia Theodoropoulou, Jiahui Wu, Jian Liu, David A. Copland, Louis M. Scott, Andrew D. Dick, Stefan Schrader, Lei Liu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 668-680 (2019)
Externí odkaz:
https://doaj.org/article/e15335f07a75454eb2e27e987aadf34a
Publikováno v:
Molecules, Vol 27, Iss 19, p 6247 (2022)
(1) Background: Colorectal cancer (CRC) is a common gastrointestinal malignancy, accounting for the second largest gastrointestinal tumor. MORC2, a newly discovered chromatin remodeling protein, plays an important role in the biological processes of
Externí odkaz:
https://doaj.org/article/d2f07eabb6f440479800dbafab202a87
Publikováno v:
Animals, Vol 10, Iss 8, p 1398 (2020)
Myostatin (MSTN) is a member of the transforming growth factor beta superfamily and is a negative regulator of myogenesis. It has been shown to function by controlling the proliferation of myoblasts. MSTN inhibition is considered as a promising treat
Externí odkaz:
https://doaj.org/article/7b733df109b545cb8364410ebd5d698b
Publikováno v:
Biomedicine & Pharmacotherapy. 155:113793
Hyperglycemia triggers metabolic and inflammatory responses, which lead to vascular inflammation and consequently induce microvascular and/or macrovascular diabetic complications. 5-bromo-3,4-dihydroxybenzaldehyde (BDB), a marine red algae-derived br