Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Kepa Ruiz-Mirazo"'
Autor:
Nino Lauber, Ondrej Tichacek, Rudrarup Bose, Christoph Flamm, Luca Leuzzi, T-Y Dora Tang, Kepa Ruiz-Mirazo, Daniele De Martino
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106300- (2023)
Summary: Physical mechanisms of phase separation in living systems play key physiological roles and have recently been the focus of intensive studies. The strongly heterogeneous nature of such phenomena poses difficult modeling challenges that requir
Externí odkaz:
https://doaj.org/article/3877b7526eb14139988ef31c4b2d3f35
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/738a959772e04c8380ae8a1e5db5b661
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The concept of identity is used both (i) to distinguish a system as a particular material entity that is conserved as such in a given environment (token-identity: i.e., identity as permanence or endurance over time), and (ii) to relate a system with
Externí odkaz:
https://doaj.org/article/0ec19f2098d34befa2d48c0bf6acedff
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1388-1395 (2017)
Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full-fl
Externí odkaz:
https://doaj.org/article/f3bec1e7131e40f3a883efc332dfa61b
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The origin-of-life problem has been traditionally conceived as the chemical challenge to find the type of molecule and free-solution reaction dynamics that could have started Darwinian evolution. Different autocatalytic and ‘self-replicati
Externí odkaz:
https://doaj.org/article/ae7f13ef328746e0a61dd268581f46d2
Autor:
Sara Murillo-Sánchez, Kepa Ruiz-Mirazo
Publikováno v:
Isegoría, Iss 55, Pp 551-575 (2016)
En este artículo se ofrece una visión de la biología sintética alternativa a los planteamientos ingenieriles que marcan gran parte de la agenda de investigación del campo. Nuestro análisis se centra en enfoques, teóricos y experimentales, cuyo
Externí odkaz:
https://doaj.org/article/d6165876ae174005aeecc5dedfbd7e58
Publikováno v:
Life, Vol 5, Iss 1, Pp 181-211 (2015)
Artificial protocellular compartments and lipid vesicles have been used as model systems to understand the origins and requirements for early cells, as well as to design encapsulated reactors for biotechnology. One prominent feature of vesicles is th
Externí odkaz:
https://doaj.org/article/2284a53d2cb6461793a790b4ba6a4832
Publikováno v:
Open Biology, Vol 7, Iss 4 (2017)
In recent years, an extension of the Darwinian framework is being considered for the study of prebiotic chemical evolution, shifting the attention from homogeneous populations of naked molecular species to populations of heterogeneous, compartmentali
Externí odkaz:
https://doaj.org/article/49967e6eb82a4683894c4791915b9ee7
Autor:
Kepa Ruiz-Mirazo, Alvaro Moreno
Publikováno v:
Mètode Science Studies Journal: Annual Review, Iss 6 (2016)
This paper argues that the question of the origin of life cannot be explained by appealing exclusively to Darwinian evolutionary mechanisms, as many experts tend to assume, but requires a profound change in perspective. Accordingly, we highlight the
Externí odkaz:
https://doaj.org/article/d9fb70d0cd42449899200ad9051b6e44
Autor:
Gabriel Piedrafita, Kepa Ruiz-Mirazo, Pierre-Alain Monnard, Athel Cornish-Bowden, Francisco Montero
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39480 (2012)
In this work we attempt to find out the extent to which realistic prebiotic compartments, such as fatty acid vesicles, would constrain the chemical network dynamics that could have sustained a minimal form of metabolism. We combine experimental and s
Externí odkaz:
https://doaj.org/article/1807a6ea0523406eae6edf68de8fa0ba