Cigarette smoke impairs the hematopoietic supportive property of mesenchymal stem cells via the production of reactive oxygen species and NLRP3 activation

Autor: Hyun Sung Park, Byung-Chul Lee, Dong-Hoon Chae, Aaron Yu, Jae Han Park, Jiyoung Heo, Myoung Hee Han, Keonwoo Cho, Joong Won Lee, Ji-Won Jung, Cynthia E. Dunbar, Mi-Kyung Oh, Kyung-Rok Yu

Publikováno v: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Background Mesenchymal stem cells (MSCs) play important roles in tissue homeostasis by providing a supportive microenvironmental niche for the hematopoietic system. Cigarette smoking induces systemic abnormalities, including an impeded recov

Externí odkaz: https://doaj.org/article/ae7830a8e0ff4921863217e71e9cca06

Cigarette smoke impairs the hematopoietic supportive property of mesenchymal stem cells via the production of reactive oxygen species and NLRP3 activation.

Autor: Park, Hyun Sung¹ (AUTHOR), Lee, Byung-Chul^2,3 (AUTHOR), Chae, Dong-Hoon¹ (AUTHOR), Yu, Aaron¹ (AUTHOR), Park, Jae Han¹ (AUTHOR), Heo, Jiyoung¹ (AUTHOR), Han, Myoung Hee¹ (AUTHOR), Cho, Keonwoo¹ (AUTHOR), Lee, Joong Won⁴ (AUTHOR), Jung, Ji-Won⁴ (AUTHOR), Dunbar, Cynthia E.⁵ (AUTHOR), Oh, Mi-Kyung¹ (AUTHOR) ipomk@snu.ac.kr, Yu, Kyung-Rok¹ (AUTHOR) cellyu@snu.ac.kr

Publikováno v: Stem Cell Research & Therapy. 5/20/2024, Vol. 15 Issue 1, p1-14. 14p.