Zobrazeno 1 - 10
of 622
pro vyhledávání: '"Keon Wook, Kang"'
Autor:
Amal Magdy, Hee-Jin Kim, Hanyong Go, Jun Min Lee, Hyun Ahm Sohn, Keeok Haam, Hyo-Jung Jung, Jong-Lyul Park, Taekyeong Yoo, Eun-Soo Kwon, Dong Hyeon Lee, Murim Choi, Keon Wook Kang, Won Kim, Mirang Kim, on behalf of the Innovative Target Exploration of NAFLD (ITEN) Consortium
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 4, Pp 824-844 (2024)
Background/Aims Blocking the complement system is a promising strategy to impede the progression of metabolic dysfunction–associated steatotic liver disease (MASLD). However, the interplay between complement and MASLD remains to be elucidated. This
Externí odkaz:
https://doaj.org/article/f8340be6f5b64e369efda5e29efcbe27
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background Breast cancer, the most prevalent cancer in women worldwide, faces treatment challenges due to drug resistance, posing a serious threat to patient survival. The present study aimed to identify the key molecules that drive drug res
Externí odkaz:
https://doaj.org/article/27e0d55456c04f368ef38a452c69308c
Autor:
Hyung Jun Kim, Seon-Pil Jin, Jooyoun Kang, So Hyeon Bae, Jung Bae Son, Jang-Hee Oh, Hyewon Youn, Seong Keun Kim, Keon Wook Kang, Jin Ho Chung
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Mitochondria are essential organelles in cellular energy metabolism and other cellular functions. Mitochondrial dysfunction is closely linked to cellular damage and can potentially contribute to the aging process. The purpose of this study w
Externí odkaz:
https://doaj.org/article/c9cb8ce1f31643d19f8cc9f79aa61db3
Autor:
Yong Jin An, Sihyang Jo, Jin-Mo Kim, Han Sun Kim, Hyun Young Kim, Sang-Min Jeon, Dawool Han, Jong In Yook, Keon Wook Kang, Sunghyouk Park
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 10, Pp 2238-2247 (2023)
Abstract Histone acetylation involves the transfer of two-carbon units to the nucleus that are embedded in low-concentration metabolites. We found that lactate, a high-concentration metabolic byproduct, can be a major carbon source for histone acetyl
Externí odkaz:
https://doaj.org/article/e69d02050b8b4d38b7788ff7308d38d4
Autor:
Hoon Young Suh, Hongyoon Choi, Sun Wook Cho, Jin Chul Paeng, Gi Jeong Cheon, Young Joo Park, Keon Wook Kang
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 17068-17077 (2023)
Abstract Introduction Iodine and FDG uptakes have been established as methods to define the biological properties of thyroid cancer. As various cells in the tumor microenvironment (TME) affect tumor metabolism, we investigated the association between
Externí odkaz:
https://doaj.org/article/32b12a2357714268814d2a8a870c4131
Autor:
Yong June Choi, Munkyung Choi, Jaewoo Park, Miso Park, Myung Jun Kim, Jae-sun Lee, Su-jin Oh, Young Joo Lee, Wan Seob Shim, Ji Won Kim, Myung Jin Kim, Yong-Chul Kim, Keon Wook Kang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116124- (2024)
Lung cancer represents a significant global health concern and stands as the leading cause of cancer-related mortality worldwide. The identification of specific genomic alterations such as EGFR and KRAS in lung cancer has paved the way for the develo
Externí odkaz:
https://doaj.org/article/6ba47a94f1b847b6a0b16d060923d93c
Autor:
So‐Yeol Yoo, Yong‐Hyeon Mun, Nae‐Won Kang, Jang Mo Koo, Dong Hwan Lee, Ji Hoon Yoo, Sang Min Lee, Seokjin Koh, Jong Chan Park, Taejung Kim, Eun Kyung Shin, Han Sol Lee, Jaehoon Sim, Keon Wook Kang, Sang Kyum Kim, Cheong‐Weon Cho, Myeong Gyu Kim, Dae‐Duk Kim, Jae‐Young Lee
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract Recent studies on osteosarcoma regimens have mainly focused on modifying the combination of antineoplastic agents rather than enhancing the therapeutic efficacy of each component. Here, an albumin nanocluster (NC)‐assisted methotrexate (MT
Externí odkaz:
https://doaj.org/article/5b0aa7f7b3d848cfb0b4051c1f285248
Autor:
Yong June Choi, Jaewoo Park, Hyoyi Choi, Su-Jin Oh, Jin-Hee Park, Miso Park, Ji Won Kim, Yoon-Gyoon Kim, Yong-Chul Kim, Myung Jin Kim, Keon Wook Kang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115066- (2023)
Acute myeloid leukemia (AML) is a prevalent form of leukemia in adults. As its survival rate is low, there is an urgent need for new therapeutic options. In AML, FMS-like tyrosine kinase 3 (FLT3) mutations are common and have negative outcomes. Howev
Externí odkaz:
https://doaj.org/article/d803e8678dd0473f9e8a0d664e2259df
Autor:
Sungwoo Bae, Joonhyung Gil, Jin Chul Paeng, Eun-Ah Park, Seung-Pyo Lee, Hongyoon Choi, Keon Wook Kang, Gi Jeong Cheon, Dong Soo Lee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract We aimed to evaluate the reliability and feasibility of visual grading systems and various quantitative indexes of [99mTc]Tc-DPD imaging for cardiac amyloidosis (CA). Patients who underwent [99mTc]Tc-DPD imaging with suspicion of CA were enr
Externí odkaz:
https://doaj.org/article/3fe24c0616484a2db2618304bdda6e12
This atlas showcases cross-sectional anatomy for the proper interpretation of images generated from PET/MRI, PET/CT, and SPECT/CT applications. Hybrid imaging is at the forefront of nuclear and molecular imaging and enhances data acquisition for the
