Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Keon Bong Oh"'
Autor:
Hyeon Yang, Bo Ram Lee, Seunghoon Lee, Sun A. Ock, Keon Bong Oh, Yong Jin Jo, Poongyeon Lee, Haesun Lee, Jae Yong Han, Sung June Byun
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract A germinal disc located on the egg yolk surface drives genetic modification. Windowed and surrogate eggshell incubation methods have been developed, but these exhibit limited abilities to generate transgenic chickens. In the present study, w
Externí odkaz:
https://doaj.org/article/537633a0711a428d887323be47457f69
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 38, Iss 4, Pp 199-208 (2023)
Background: Canine induced pluripotent stem cells (iPSCs) are an attractive source for veterinary regenerative medicine, disease modeling, and drug development. Here we used vitamin C (Vc) to improve the reprogramming efficiency of canine iPSCs, and
Externí odkaz:
https://doaj.org/article/19488220a473438c8dfd463ffa4a3600
Autor:
Byeonghwi Lim, Min-Jae Jang, Seung-Mi Oh, Jin Gu No, Jungjae Lee, Sang Eun Kim, Sun A. Ock, Ik Jin Yun, Junseok Kim, Hyun Keun Chee, Wan Seop Kim, Hee Jung Kang, Kahee Cho, Keon Bong Oh, Jun-Mo Kim
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 234-248 (2023)
ABSTRACTCardiac xenotransplantation is the potential treatment for end-stage heart failure, but the allogenic organ supply needs to catch up to clinical demand. Therefore, genetically-modified porcine heart xenotransplantation could be a potential al
Externí odkaz:
https://doaj.org/article/a2aaf07901554626a3d083674bb0c526
Autor:
Won Kil Lee, Hwi-Cheul Lee, Seunghoon Lee, Haesun Lee, Sang Eun Kim, Minguk Lee, Jin-Gu No, Keon Bong Oh, Poongyeon Lee
Publikováno v:
Life, Vol 14, Iss 9, p 1132 (2024)
Blood analysis plays a pivotal role in assessing the health of laboratory animals, including pigs. This study investigated the hematological profiles of transgenic pigs of the MGH breed for xenotransplantation, focusing on the effect of housing condi
Externí odkaz:
https://doaj.org/article/8012e884b5114272a239c1b9c528dce2
Publikováno v:
Life, Vol 14, Iss 9, p 1054 (2024)
The purpose of this study was to develop a monoclonal antibody (mAb) that can identify porcine dendritic cells (DCs) that have differentiated from bone marrow progenitor cells. Hybridoma technology was used to obtain mAbs, and bone marrow-derived DCs
Externí odkaz:
https://doaj.org/article/65db9bd12295459696da3f27fff699fe
Autor:
Hyeon Yang, Sun A. Ock, Seunghoon Lee, Mi-Ryung Park, Seokho Kim, Jingu No, Keon Bong Oh, Hayeon Wi, Sun Keun Jung, Yong Jin Jo, Bo Ram Lee, Minguk Lee, Sung June Byun
Publikováno v:
Poultry Science, Vol 102, Iss 8, Pp 102802- (2023)
ABSTRACT: To date, many transgenic (TG) chicken lines have been developed, but few studies have performed a comparative analysis of their mortality, growth, and egg productivity. Previously, we reported the production of 3D8 scFv TG chickens showing
Externí odkaz:
https://doaj.org/article/24f7a545c41a49eca83a113045bdd4e9
Autor:
Imran Ullah, Yurianna Shin, Yeongji Kim, Keon Bong Oh, Seongsoo Hwang, Young-Im Kim, Jeong Woong Lee, Tai-Young Hur, Seunghoon Lee, Sun A Ock
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background The liver is one of the vital organs involved in detoxification and metabolism. The sex-based differences between the functionality of male and female liver have been previously reported, i.e., male’s liver are good in alcohol c
Externí odkaz:
https://doaj.org/article/b4e4ec9984e54b4c97b29d05a8651538
Autor:
Hyeon Yang, Bo Ram Lee, Sun Keun Jung, Hwi-Cheul Lee, Yong Jin Jo, Jingu No, Ji-Youn Kim, Haesun Lee, Seokho Kim, Keon Bong Oh, Sung June Byun
Publikováno v:
Poultry Science, Vol 101, Iss 5, Pp 101733- (2022)
ABSTRACT: A surrogate eggshell incubation system is a well-defined method to apply to avian genetic modification. In this study, we tried to investigate whether the egg weight differences between donor and surrogate eggs have an effect on donor viabi
Externí odkaz:
https://doaj.org/article/a1344fa7f5b540f6856a9c412dc5d982
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundTriple knockout (TKO) donor pigs lacking alpha-1,3-galactose (Gal), N-glycolylneuraminic acid (Neu5Gc), and Sd(a) expressions were developed to improve the clinical success of xenotransplantation. Neu5Gc, a sialic acid expressed on cell sur
Externí odkaz:
https://doaj.org/article/8899137a5bfc426e9cb9864aa6aea444
Publikováno v:
Asian-Australasian Journal of Animal Sciences, Vol 33, Iss 11, Pp 1837-1847 (2020)
Objective To evaluate the pancreatic differentiation potential of α-1,3-galactosyltransferase knockout (GalTKO) pig-derived bone marrow-derived mesenchymal stem cells (BM-MSCs) using epigenetic modifiers with different pancreatic induction media. Me
Externí odkaz:
https://doaj.org/article/ee78364c38c14806bfbd85623e2c8e51