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Repurposing Atovaquone as a Therapeutic against Acute Myeloid Leukemia (AML): Combination with Conventional Chemotherapy Is Feasible and Well Tolerated.

Autor: Stevens AM; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Schafer ES; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Li M; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Terrell M; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Rashid R; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Paek H; Department of Pharmacy, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Bernhardt MB; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Weisnicht A; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA., Smith WT; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Keogh NJ; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Alozie MC; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Oviedo HH; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Gonzalez AK; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Ilangovan T; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Mangubat-Medina A; Department of Chemistry, Rice University, Houston, TX 77005, USA., Wang H; Department of Chemistry, Rice University, Houston, TX 77005, USA., Jo E; Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Rabik CA; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA., Bocchini C; Department of Pediatric Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA., Hilsenbeck S; Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Ball ZT; Department of Chemistry, Rice University, Houston, TX 77005, USA., Cooper TM; Cancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, WA 98105, USA., Redell MS; Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.

Publikováno v: Cancers [Cancers (Basel)] 2023 Feb 20; Vol. 15 (4). Date of Electronic Publication: 2023 Feb 20.