Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Kenzo Yahata"'
Autor:
Raphael J. Zachmann, Kenzo Yahata, Mira Holzheimer, Maxime Jarret, Cornelia Wirtz, Alois Fürstner
Publikováno v:
Journal of the American Chemical Society. 145:2584-2595
Publikováno v:
European Journal of Organic Chemistry. 2021:4417-4422
Autor:
Masahiro Egi, Go Itoh, Takashi Ikawa, Shuji Akai, Koji Sugiyama, Shuhei Hori, Kenzo Yahata, Sho Ishida, Chiharu Yuki
Publikováno v:
Synlett. 32:1187-1191
4,5,6,7-Tetrahydroisobenzofurans, corresponding to the AC(D)E ring structure of viridin and equipped with required substituents on the A-ring, were synthesized with high regio- and stereoselectivities via the Diels–Alder adduct of a furan derivativ
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:332-335
Herein, we describe a novel synthetic method for 2,5-disubstituted tetrazoles from 5-substituted tetrazoles using cobalt-catalyzed intermolecular hydroamination reaction of nonactivated olefins. Owing to its mild conditions, the method enabled the us
Publikováno v:
Organic Letters. 22:1199-1203
Herein, we describe the generation of an organochromium-type carbanion species from a non-activated C-H bond and its nucleophilic addition to aldehydes. The catalytic carbanion generation occurred through formal deprotonation of a non-activated C-H b
Publikováno v:
Organic Letters. 22:598-603
Cobalt-catalyzed Markovnikov-selective hydroamination of nonactivated olefins was developed. Hydrogen atom transfer from a catalytically generated cobalt(III)–hydride complex to the olefins proceed...
Autor:
Takashi Ikawa, Yuto Masuda, Akito Heguri, Yasuteru Shigeta, Hiroshi Aoyama, Akira Takagi, Hiroaki Tokiwa, Kenzo Yahata, Shuji Akai, Yutaka Fukumoto, Tomonari Murakami, Yuta Yamamoto
Publikováno v:
Journal of the American Chemical Society. 143(29)
In recent years, London dispersion interactions, which are the attractive component of the van der Waals potential, have been found to play an important role in controlling the regio- and/or stereoselectivity of various reactions. Particularly, the d
Autor:
Yuki Sato, Ken Ito, Yoshito Kishi, Takashi Fukuyama, Takeo Sasaki, Isao Ohashi, Kentaro Iso, Takanori Abe, Tsuyoshi Akagi, Kenzo Yahata, Minetaka Isomura, Makoto Asano, Yosuke Kaburagi, Yasunobu Matsumoto, Fumiyoshi Matsuura, Yusuke Miyashita, Takashi Owa, Satoshi Kawano, Kazunobu Kira, Akira Yokoi, Osamu Asano
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Despite their outstanding antitumour activity in mice, the limited supply from the natural sources has prevented drug discovery/development based on intact halichondrins. We achieved a total synthesis of C52-halichondrin-B amine (E7130) on a >10 g sc
Publikováno v:
Chemicalpharmaceutical bulletin. 68(4)
Ketones are a fundamental functionality found throughout a range of natural and synthetic compounds, making their synthesis essential throughout the chemical disciplines. Herein, we describe a one-pot synthesis of ketones via decatungstate-mediated f
Publikováno v:
Organic letters. 22(2)
Cobalt-catalyzed Markovnikov-selective hydroamination of nonactivated olefins was developed. Hydrogen atom transfer from a catalytically generated cobalt(III)-hydride complex to the olefins proceeded regioselectively, and the nucleophilic addition of