Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Kenzo, Tokunaga"'
Autor:
MST Monira Begum, Kimiko Ichihara, Otowa Takahashi, Hesham Nasser, Michael Jonathan, Kenzo Tokunaga, Isao Yoshida, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Kei Sato, Terumasa Ikeda, Keita Matsuno, Naganori Nao, Hirofumi Sawa, Shinya Tanaka, Masumi Tsuda, Lei Wang, Yoshikata Oda, Zannatul Ferdous, Kenji Shishido, Takasuke Fukuhara, Tomokazu Tamura, Rigel Suzuki, Saori Suzuki, Hayato Ito, Jumpei Ito, Yu Kaku, Naoko Misawa, Arnon Plianchaisuk, Ziyi Guo, Alfredo Jr. Hinay, Keiya Uriu, Yusuke Kosugi, Shigeru Fujita, Jarel Elgin Mendoza Tolentino, Luo Chen, Lin Pan, Mai Suganami, Mika Chiba, Ryo Yoshimura, Kyoko Yasuda, Keiko Iida, Naomi Ohsumi, Adam Patrick Strange, Hiroyuki Asakura, So Nakagawa, Akifumi Takaori-Kondo, Kotaro Shirakawa, Kayoko Nagata, Ryosuke Nomura, Yoshihito Horisawa, Yusuke Tashiro, Yugo Kawai, Kazuo Takayama, Rina Hashimoto, Sayaka Deguchi, Yukio Watanabe, Ayaka Sakamoto, Naoko Yasuhara, Takao Hashiguchi, Tateki Suzuki, Kanako Kimura, Jiei Sasaki, Yukari Nakajima, Hisano Yajima, Takashi Irie, Ryoko Kawabata, Kaori Tabata, Ryo Shimizu, Yuka Mugita, Takamasa Ueno, Chihiro Motozono, Mako Toyoda, Akatsuki Saito, Maya Shofa, Yuki Shibatani, Tomoko Nishiuchi
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
IntroductionThe severe acute respiratory syndrome coronavirus (SARS-CoV-2) spike (S) protein is essential in mediating membrane fusion of the virus with the target cells. Several reports demonstrated that SARS-CoV-2 S protein fusogenicity is reported
Externí odkaz:
https://doaj.org/article/5d2678f123154258a7ff9b66e6f6851e
Autor:
Takuya Tada, Yanzhao Zhang, Dechuan Kong, Michiko Tanaka, Weitong Yao, Masanori Kameoka, Takamasa Ueno, Hideaki Fujita, Kenzo Tokunaga
Publikováno v:
Cells, Vol 13, Iss 8, p 698 (2024)
The cellular transmembrane protein MARCH8 impedes the incorporation of various viral envelope glycoproteins, such as the HIV-1 envelope glycoprotein (Env) and vesicular stomatitis virus G-glycoprotein (VSV-G), into virions by downregulating them from
Externí odkaz:
https://doaj.org/article/0fd0ce7a18ee460995f4a2e79730c845
Autor:
Ryota Ueda, Rina Hashimoto, Yuki Fujii, José C. J. M. D. S. Menezes, Hirotaka Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki, Tomonori Motokawa, Kenzo Tokunaga, Hideaki Fujita
Publikováno v:
Membranes, Vol 14, Iss 2, p 43 (2024)
Lysosomal degradation of tyrosinase, a pivotal enzyme in melanin synthesis, negatively impacts melanogenesis in melanocytes. Nevertheless, the precise molecular mechanisms by which lysosomes target tyrosinase have remained elusive. Here, we identify
Externí odkaz:
https://doaj.org/article/ba5fa2b7186d45ba9045462d47b7d343
Autor:
Seiya Ozono, Yanzhao Zhang, Hirotaka Ode, Kaori Sano, Toong Seng Tan, Kazuo Imai, Kazuyasu Miyoshi, Satoshi Kishigami, Takamasa Ueno, Yasumasa Iwatani, Tadaki Suzuki, Kenzo Tokunaga
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
SARS-CoV-2 D614G spike protein mutation is one of the predominant circulating vital mutants. Here, Ozono et al. demonstrate that D614G mutation increases in vitro cell entry by acquiring higher affinity to ACE2.
Externí odkaz:
https://doaj.org/article/acf66950162a40c68bcc2ed12d14299c
Autor:
Yanzhao Zhang, Seiya Ozono, Takuya Tada, Minoru Tobiume, Masanori Kameoka, Satoshi Kishigami, Hideaki Fujita, Kenzo Tokunaga
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The host transmembrane protein MARCH8 is a RING finger E3 ubiquitin ligase that downregulates various host transmembrane proteins, such as MHC-II. We have recently reported that MARCH8 expression in virus-producing cells impairs viral infect
Externí odkaz:
https://doaj.org/article/1e01e0603bb145aba4f812150395ff38
Autor:
Akina Nakamura, Tomohiro Kotaki, Yurie Nagai, Shunta Takazawa, Kenzo Tokunaga, Masanori Kameoka
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global threat. To forestall the pandemic, developing safe and effective vaccines is necessary. Because of the rapid
Externí odkaz:
https://doaj.org/article/cc887e63b6944871b219c923b543a453
Autor:
George P. Judicate, Godfrey Barabona, Doreen Kamori, Macdonald Mahiti, Toong Seng Tan, Seiya Ozono, Amina Shaban Mgunya, Takeo Kuwata, Shuzo Matsushita, Bruno Sunguya, Eligius Lyamuya, Kenzo Tokunaga, Takamasa Ueno
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
HIV human immunodeficiency virus type I (HIV-1) entry inhibitor potency is dependent on viral co-receptor tropisms and thereby tropism determination is clinically important. However, phenotypic tropisms of HIV-1 non-B subtypes have been poorly invest
Externí odkaz:
https://doaj.org/article/499c7fa3d48e4fb5b497bd6d6ae2e7af
Publikováno v:
eLife, Vol 9 (2020)
Membrane-associated RING-CH 8 (MARCH8) inhibits infection with both HIV-1 and vesicular stomatitis virus G-glycoprotein (VSV-G)-pseudotyped viruses by reducing virion incorporation of envelope glycoproteins. The molecular mechanisms by which MARCH8 t
Externí odkaz:
https://doaj.org/article/fdc935eb3b76421b943a4f552634bf19
Autor:
Begum, M. S. T. Monira, Kimiko Ichihara, Otowa Takahashi, Nasser, Hesham, Jonathan, Michael, Kenzo Tokunaga, Isao Yoshida, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Kei Sato, Terumasa Ikeda
Publikováno v:
Frontiers in Virology; 2024, p1-15, 15p
Publikováno v:
Viral Genome Methods ISBN: 9781003420163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db5c614796baf441cdf5f42a11cb4dd7
https://doi.org/10.1201/9781003420163-4
https://doi.org/10.1201/9781003420163-4
