Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Kenzo, Takagi"'
Autor:
Masaya Fukuda, Kiyoyuki Kitaichi, Fumie Abe, Yohei Fujimoto, Kenji Takagi, Kenzo Takagi, Tsuneo Morishima, Takaaki Hasegawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 4, Pp 525-532 (2005)
It is well accepted that bacterial and virus infections elevate the levels of cytokines in serum and cerebrospinal fluids. Such high levels of cytokines might alter the integrity of the blood-brain barrier (BBB) and/or blood-cerebrospinal fluid barri
Externí odkaz:
https://doaj.org/article/cc718446de694a5cb60c71452c3c09a4
Autor:
Michitaka, Shichijo 1, Yasuo, Shimizu 2, Kenju, Hiramatsu 2, Michinori, Togawa 1, Naoki, Inagaki 1, Kenzo, Takagi 2, Hiroichi, Nagai 1, *
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(4):501-504
Publikováno v:
Arzneimittelforschung. 52:803-812
To examine the response to beta-adrenergic receptor agonists (beta-agonists) following prolonged activation of the stimulatory G protein of adenylyl cyclase (Gs), relaxation by isoproterenol (isoprenaline, CAS 949-36-0) and formoterol (CAS 73573-87-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ffc0ff77a3204eee5e3709d64e22c5
https://doi.org/10.1055/s-0031-1299971
https://doi.org/10.1055/s-0031-1299971
Autor:
Joe Shindoh, Masashi Kondo, Kazuyoshi Imaizumi, Syuichi Matsumoto, Hiroaki Kume, Yoshinori Hasegawa, Kenji Baba, Kenzo Takagi, Motoshi Ichikawa, Kensuke Kataoka, Yoshimasa Tanikawa, Yasunobu Noda, Kiyoshi Suzuki, Hiroyuki Taniguchi, Yuichiro Shindo, Ryujiro Suzuki
Publikováno v:
Lung Cancer. 69:319-322
We conducted a phase II trial to evaluate the safety and efficacy of weekly paclitaxel in patients with resistant or relapsed non-small cell lung cancer (NSCLC) treated with docetaxel and carboplatin. Thirty-two NSCLC patients at a median age of 58.0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4687582bffbac83a400a81aa3a02abf
https://doi.org/10.1016/j.lungcan.2009.11.021
https://doi.org/10.1016/j.lungcan.2009.11.021
Autor:
Yoshinori Hasegawa, Kenzo Takagi, Kazuyoshi Imaizumi, Naozumi Hashimoto, Masataka Shibasaki, Tsutomu Kawabe, Katsunori Hashimoto, Yuta Hayashi, Nobuaki Ozaki, Toyoharu Yokoi, Kaoru Shimokata, Masakazu Okamoto
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 40:536-542
Although Pneumocystis infection might be one of the causes of secondary pulmonary alveolar proteinosis (PAP), the mechanism of its pathogenesis is uncertain. We analyzed a mouse model of secondary PAP resulting from Pneumocystis infection using mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8dca5e4909e6cbdc9233077dbae070
https://doi.org/10.1165/rcmb.2008-0103oc
https://doi.org/10.1165/rcmb.2008-0103oc
Autor:
Miyoko Matsushima, Etsuko Hirose, Takaaki Hasegawa, Kenji Baba, Fumie Abe, Tsutomu Kawabe, Kenzo Takagi, Yui Ota, Miyuki Ogawa, Yoshinori Hasegawa
Publikováno v:
Inflammation Research. 58:705-715
We investigated the involvement of heme oxygenase (HO)-1 in the anti-allergic action of quercetin against degranulation of rat basophilic leukemia (RBL-2H3) cells, rat peritoneal mast cells, and mouse bone marrow-derived mast cells.The strength of al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f42c527298e2239df7f608d9c82959f
https://doi.org/10.1007/s00011-009-0039-1
https://doi.org/10.1007/s00011-009-0039-1
Autor:
Yuta Hayashi, Keiko Ishigami, Toshinobu Nakamura, Miyoko Matsushima, Kazuyoshi Imaizumi, Naozumi Hashimoto, Etsuko Hirose, Yoshinori Hasegawa, Kenji Baba, Yui Ota, Kenzo Takagi, Tsutomu Kawabe, Tatsuya Hirayama
Publikováno v:
Inflammation. 32:99-108
Kaempferol is one of the most commonly found dietary flavonoids. The exposure to kaempferol is known to inhibit degranulation from mast cells, but the inhibitory mechanism of degranulation has not been clarified yet. In this study, we investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402394480db6ed55e3ff0911c7a8ce11
https://doi.org/10.1007/s10753-009-9108-4
https://doi.org/10.1007/s10753-009-9108-4
Autor:
Yoshinori Hasegawa, Kenzo Takagi, Masakazu Okamoto, Kazuyoshi Imaizumi, Kaoru Shimokata, Atsushi Sumida, Hiroshi Yatsuya, Tsutomu Kawabe, Toyoharu Yokoi, Naozumi Hashimoto
Publikováno v:
Archives of Medical Research. 39:503-510
Background Inflammatory response in pulmonary fibrosis closely resembles a T-helper (Th) 2 immune response. For recruitment to an inflammatory lesion, the majority of Th1 cells express CXC chemokine receptor 3, recognizing monokine induced by interfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdb72b624e9ecf0a2dead0d8b150064
https://doi.org/10.1016/j.arcmed.2008.02.005
https://doi.org/10.1016/j.arcmed.2008.02.005
Autor:
Takaaki Hasegawa, Toyoharu Yokoi, Kiyoyuki Kitaichi, Katsunori Hashimoto, Norio Ozaki, Yukiko Ito, Hironao Nakayama, Kenji Takagi, Tuneyuki Yamamoto, Kenzo Takagi
Publikováno v:
Brain Research. 1184:260-269
Organic cation transporter-3 (OCT3) is expressed in several tissues including the brain. We have previously demonstrated that rats with behavioral sensitization to methamphetamine (METH) increased the brain penetration of METH with decreased expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97521f8c95ddacc1a0557963fe71915
https://doi.org/10.1016/j.brainres.2007.09.072
https://doi.org/10.1016/j.brainres.2007.09.072
Autor:
Masataka Shibazaki, Kazuyoshi Imaizumi, Kenzo Takagi, Yoshinori Hasegawa, Tsutomu Kawabe, Naozumi Hashimoto, Atsushi Sumida, Kaoru Shimokata, Masakazu Okamoto
Publikováno v:
Respirology. 12:581-584
Background and objectives: Macrophage-derived chemokine (MDC/CCL22) is recognized as a T-helper (Th) 2-type chemokine. Both malignant and tuberculous pleural effusions are typically lymphocytic pleural effusions. Tuberculous pleural effusions have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6409b6cb8f3c2629d328cc7b1c3cfd47
https://doi.org/10.1111/j.1440-1843.2007.01059.x
https://doi.org/10.1111/j.1440-1843.2007.01059.x