Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kenzie Birse"'
Autor:
Christina Farr Zuend, Alana Lamont, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Kateryna Kratzer, Peter McQueen, Michelle Perner, Hossaena Ayele, Sarah Mutch, Alicia R. Berard, John J. Schellenberg, Faruk Senturk, Stuart McCorrister, Garrett Westmacott, Fran Mulhall, Bonnie Sandberg, Adelicia Yu, Margaret Burnett, Vanessa Poliquin, Adam D. Burgener
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome hav
Externí odkaz:
https://doaj.org/article/1af3ea388c5e4f578c6b6afe6c865734
Autor:
Alicia R. Berard, Douglas K. Brubaker, Kenzie Birse, Alana Lamont, Romel D. Mackelprang, Laura Noël-Romas, Michelle Perner, Xuanlin Hou, Elizabeth Irungu, Nelly Mugo, Samantha Knodel, Timothy R. Muwonge, Elly Katabira, Sean M. Hughes, Claire Levy, Fernanda L. Calienes, Douglas A. Lauffenburger, Jared M. Baeten, Connie Celum, Florian Hladik, Jairam Lingappa, Adam D. Burgener
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112474- (2023)
Summary: Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, t
Externí odkaz:
https://doaj.org/article/7e7c96530b7143479c58b3f44a85ad62
Autor:
Alessandra Borgognone, Marc Noguera-Julian, Bruna Oriol, Laura Noël-Romas, Marta Ruiz-Riol, Yolanda Guillén, Mariona Parera, Maria Casadellà, Clara Duran, Maria C. Puertas, Francesc Català-Moll, Marlon De Leon, Samantha Knodel, Kenzie Birse, Christian Manzardo, José M. Miró, Bonaventura Clotet, Javier Martinez-Picado, José Moltó, Beatriz Mothe, Adam Burgener, Christian Brander, Roger Paredes, the BCN02 Study Group
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen with
Externí odkaz:
https://doaj.org/article/f4eb4630f5eb4505a01baefcff14f0eb
Autor:
Cecilia Svanberg, Rada Ellegård, Elisa Crisci, Mohammad Khalid, Ninnie Borendal Wodlin, Maria Svenvik, Sofia Nyström, Kenzie Birse, Adam Burgener, Esaki M. Shankar, Marie Larsson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/01349441e35b4dc1b43546b5d2ea39f8
Autor:
Cecilia Svanberg, Rada Ellegård, Elisa Crisci, Mohammad Khalid, Ninnie Borendal Wodlin, Maria Svenvik, Sofia Nyström, Kenzie Birse, Adam Burgener, Esaki M. Shankar, Marie Larsson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Genital mucosal transmission is the most common route of HIV spread. The initial responses triggered at the site of viral entry are reportedly affected by host factors, especially complement components present at the site, and this will have profound
Externí odkaz:
https://doaj.org/article/dd35da5d89b54e20a0e1987062327f06
Autor:
Laura Noël-Romas, Michelle Perner, Refilwe Molatlhegi, Christina Farr Zuend, Amanda Mabhula, Sarah Hoger, Alana Lamont, Kenzie Birse, Alicia Berard, Stuart McCorrister, Garett Westmacott, Al Leslie, Vanessa Poliquin, Renee Heffron, Lyle R McKinnon, Adam D Burgener
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009097 (2020)
Alterations to the mucosal environment of the female genital tract, such as genital inflammation, have been associated with increased HIV acquisition in women. As the microbiome and hormonal contraceptives can affect vaginal mucosal immunity, we hypo
Externí odkaz:
https://doaj.org/article/4aa8c2a61e09450bbe96238e45e65caa
Autor:
Sean M. Hughes, Claire N. Levy, Fernanda L. Calienes, Joanne D. Stekler, Urvashi Pandey, Lucia Vojtech, Alicia R. Berard, Kenzie Birse, Laura Noël-Romas, Brian Richardson, Jackelyn B. Golden, Michael Cartwright, Ann C. Collier, Claire E. Stevens, Marcel E. Curlin, Timothy H. Holtz, Nelly Mugo, Elizabeth Irungu, Elly Katabira, Timothy Muwonge, Javier R. Lama, Jared M. Baeten, Adam Burgener, Jairam R. Lingappa, M. Juliana McElrath, Romel Mackelprang, Ian McGowan, Ross D. Cranston, Mark J. Cameron, Florian Hladik
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 6, Pp 100096- (2020)
Summary: Tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) are used for HIV treatment and prevention. Previously, we found that topical rectal tenofovir gel caused immunological changes in the mucosa. Here, we assess the effect of oral TDF/
Externí odkaz:
https://doaj.org/article/fc2ea90cdfe548fd8b58abc0db29d044
Autor:
Alexander S Zevin, Irene Y Xie, Kenzie Birse, Kelly Arnold, Laura Romas, Garrett Westmacott, Richard M Novak, Stuart McCorrister, Lyle R McKinnon, Craig R Cohen, Romel Mackelprang, Jairam Lingappa, Doug A Lauffenburger, Nichole R Klatt, Adam D Burgener
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005889 (2016)
The mechanism(s) by which bacterial communities impact susceptibility to infectious diseases, such as HIV, and maintain female genital tract (FGT) health are poorly understood. Evaluation of FGT bacteria has predominantly been limited to studies of s
Externí odkaz:
https://doaj.org/article/20431824830346c0951f09ead965baef
Autor:
Yiran Wang, Laura Noël-Romas, Michelle Perner, Samantha Knodel, Refilwe Molatlhegi, Sarah Hoger, Kenzie Birse, Christina Farr Zuend, Lyle R McKinnon, Adam D Burgener
Publikováno v:
Clinical Infectious Diseases. 76:1372-1381
Background Adolescent girls and young women aged 15‒24 years in sub-Saharan Africa are at disproportionate risk of human immunodeficiency virus (HIV) infection. Given the known association between vaginal microbial dysbiosis and HIV susceptibility,
Autor:
Marina Costa-Fujishima, Atta Yazdanpanah, Samantha Horne, Alana Lamont, Paul Lopez, Christina Farr Zuend, Kenzie Birse, Morgan Taverner, Riley Greenslade, Max Abou, Laura Noel-Romas, Bernard Abrenica, Oluwaseun Ajibola, Nnamdi Ikeogu, Ruey-Chyi Su, Lyle R. McKinnon, Helen Pymar, Vanessa Poliquin, Alicia R. Berard, Adam D. Burgener, Thomas T. Murooka
Publikováno v:
Mucosal Immunology.