Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kenzaburo Yamaji"'
Autor:
Masamichi Kimura, Koji Nishikawa, Yosuke Osawa, Jun Imamura, Kenzaburo Yamaji, Kenichi Harada, Hiroshi Yatsuhashi, Kazumoto Murata, Kouichi Miura, Atsushi Tanaka, Tatsuya Kanto, Michinori Kohara, Terumi Kamisawa, Kiminori Kimura
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2732-2747 (2022)
Abstract Chronic cholestatic liver diseases are characterized by injury of the bile ducts and hepatocytes caused by accumulated bile acids (BAs) and inflammation. Wnt/β‐catenin signaling is implicated in organ fibrosis; however, its role in choles
Externí odkaz:
https://doaj.org/article/d5276f048b864db68f6d4c442a93004d
Autor:
Sakiko Toyama, Tomoko Honda, Sadahiro Iwabuchi, Shinichi Hashimoto, Kenzaburo Yamaji, Yuko Tokunaga, Yusuke Matsumoto, Hideya Kawaji, Takashi Miyazaki, Yoshiaki Kikkawa, Michinori Kohara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intranasal vaccines that elicit mucosal immunity are deemed effective against respiratory tract infections such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but their ability to induce humoral immunity characterized by immunoglobu
Externí odkaz:
https://doaj.org/article/36f123777df6497f99fe3e9525a11e9a
Autor:
Takahiro Sanada, Tomoko Honda, Fumihiko Yasui, Kenzaburo Yamaji, Tsubasa Munakata, Naoki Yamamoto, Makoto Kurano, Yusuke Matsumoto, Risa Kohno, Sakiko Toyama, Yoshiro Kishi, Takuro Horibe, Yudai Kaneko, Mayumi Kakegawa, Kazushige Fukui, Takeshi Kawamura, Wang Daming, Chungen Qian, Fuzhen Xia, Fan He, Syudo Yamasaki, Atsushi Nishida, Takayuki Harada, Masahiko Higa, Yuko Tokunaga, Asako Takagi, Masanari Itokawa, Tatsuhiko Kodama, Michinori Kohara
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 2, Pp 105-111 (2022)
Background: Tokyo, the capital of Japan, is a densely populated city of >13 million people, so the population is at high risk of epidemic severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. A serologic survey of anti–SARS-CoV-2 IgG would
Externí odkaz:
https://doaj.org/article/2e7affd943ba41348ac614ec138430f4
Autor:
Sadahiro Iwabuchi, Tomohide Tsukahara, Toshitugu Okayama, Masahiro Kitabatake, Hideki Motobayashi, Shigeyuki Shichino, Tadashi Imafuku, Kenzaburo Yamaji, Kyohei Miyamoto, Shinobu Tamura, Satoshi Ueha, Toshihiro Ito, Shin-ichi Murata, Toshikazu Kondo, Kazuho Ikeo, Yutaka Suzuki, Kouji Matsushima, Michinori Kohara, Toshihiko Torigoe, Hiroki Yamaue, Shinichi Hashimoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neutralizing antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being developed world over. We investigated the possibility of producing artificial antibodies from the formalin fixation and paraffin-embedding (FFP
Externí odkaz:
https://doaj.org/article/32149fe894984f60b5857c5a88f4c29c
Autor:
Hirohito Ishigaki, Fumihiko Yasui, Misako Nakayama, Akinori Endo, Naoki Yamamoto, Kenzaburo Yamaji, Cong Thanh Nguyen, Yoshinori Kitagawa, Takahiro Sanada, Tomoko Honda, Tsubasa Munakata, Masahiko Higa, Sakiko Toyama, Risa Kono, Asako Takagi, Yusuke Matsumoto, Aya Koseki, Kaori Hayashi, Masanori Shiohara, Koji Ishii, Yasushi Saeki, Yasushi Itoh, Michinori Kohara
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
As long as the coronavirus disease-2019 (COVID-19) pandemic continues, new variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) with altered antigenicity will emerge. The development of vaccines that elicit robust, broad, and dura
Externí odkaz:
https://doaj.org/article/d865af51add941049c1d7ce1c10a2560
Autor:
Makoto Saito, Yasushi Itoh, Fumihiko Yasui, Tsubasa Munakata, Daisuke Yamane, Makoto Ozawa, Risa Ito, Takayuki Katoh, Hirohito Ishigaki, Misako Nakayama, Shintaro Shichinohe, Kenzaburo Yamaji, Naoki Yamamoto, Ai Ikejiri, Tomoko Honda, Takahiro Sanada, Yoshihiro Sakoda, Hiroshi Kida, Thi Quynh Mai Le, Yoshihiro Kawaoka, Kazumasa Ogasawara, Kyoko Tsukiyama-Kohara, Hiroaki Suga, Michinori Kohara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Here, the authors report bi-functional, wide tropic macrocycles that bind the influenza viral envelope protein hemagglutinin and inhibit virus infection by blocking adsorption and fusion and show efficacy in preventing severe pneumonia at later stage
Externí odkaz:
https://doaj.org/article/c9870560bd824a40938a1a8131ac4429
Autor:
Tomoko Honda, Sumiko Gomi, Daisuke Yamane, Fumihiko Yasui, Takuya Yamamoto, Tsubasa Munakata, Yasushi Itoh, Kazumasa Ogasawara, Takahiro Sanada, Kenzaburo Yamaji, Yasuhiro Yasutomi, Kyoko Tsukiyama-Kohara, Michinori Kohara
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Influenza virus HA-specific antibodies can be detected via the hemagglutination inhibition (HI) assay, the neutralization (NT) assay, and the enzyme-linked immunosorbent assay (ELISA). However, these assays have some drawbacks, including narrow dynam
Externí odkaz:
https://doaj.org/article/4c8983ceadeb457a9300b83eeaa4233b
Autor:
Yuko Tokunaga, Yosuke Osawa, Takahiro Ohtsuki, Yukiko Hayashi, Kenzaburo Yamaji, Daisuke Yamane, Mitsuko Hara, Keisuke Munekata, Kyoko Tsukiyama-Kohara, Tsunekazu Hishima, Soichi Kojima, Kiminori Kimura, Michinori Kohara
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Chronic hepatitis C virus (HCV) infection is one of the major causes of serious liver diseases, including liver cirrhosis. There are no anti-fibrotic drugs with efficacy against liver cirrhosis. Wnt/β-catenin signaling has been implicated i
Externí odkaz:
https://doaj.org/article/a5328ca8ed1a462090583dbee4a72a39
Autor:
Atsushi Nishida, Masahiko Higa, Naoki Yamamoto, Tsubasa Munakata, Mayumi Kakegawa, Makoto Kurano, Yuko Tokunaga, Takuro Horibe, Wang Da-ming, Kenzaburo Yamaji, Chungen Qian, Takeshi Kawamura, Fuzhen Xia, Masanari Itokawa, Fan He, Fukui K, Sakiko Toyama, Tatsuhiko Kodama, Takahiro Sanada, Tomoko Honda, Michinori Kohara, Syudo Yamasaki, Fumihiko Yasui, Takayuki Harada, Yoshiro Kishi, Risa Kohno, Yudai Kaneko, Yusuke Matsumoto, Asako Takagi
Publikováno v:
Journal of Epidemiology
Journal of Epidemiology, Vol 32, Iss 2, Pp 105-111 (2022)
Journal of Epidemiology, Vol 32, Iss 2, Pp 105-111 (2022)
Background: Tokyo, the capital of Japan, is a densely populated city of >13 million people, so the population is at high risk of epidemic severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. A serologic survey of anti–SARS-CoV-2 IgG would
Autor:
Takahiro Sanada, Tomoko Honda, Masahiko Higa, Kenzaburo Yamaji, Fumihiko Yasui, Michinori Kohara
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
Booster vaccinations against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being promoted worldwide to counter the coronavirus disease 2019 (COVID-19) pandemic. In this study, we analyzed the longitudinal effect of the third BNT162