Liquorice and glycyrrhetinic acid increase DHEA and deoxycorticosterone levels in vivo and in vitro by inhibiting adrenal SULT2A1 activity

Autor: Al-Dujaili, E.A.S., Kenyon, C.J., Nicol, M.R., Mason, J.I.

Publikováno v: In Molecular and Cellular Endocrinology 10 April 2011 336(1-2):102-109

Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish

Autor: Wilson, K.S., Tucker, C.S., Al-Dujaili, E.A.S., Holmes, M.C., Hadoke, P.W.F., Kenyon, C.J., Denvir, M.A.

Glucocorticoids (GCs) in utero influence embryonic development with consequent programmed effects on adult physiology and pathophysiology and altered susceptibility to cardiovascular disease. However, in viviparous species, studies of these processes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1a65d6f796d953bd3781c3a7abea1631
https://eprints.gla.ac.uk/123755/1/123755.pdf

Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes:a role for PGC-1α

Autor: Rog-Zielinska, E.A., Craig, M-A, Manning, J.R., Richardson, R.V., Gowans, G.J., Dunbar, D.R., Gharbi, K., Kenyon, C.J., Holmes, M.C., Hardie, D.G., Smith, G.L., Chapman, K.E.

Publikováno v: Rog-Zielinska, E A, Craig, M-A, Manning, J, Richardson, R V, Gowans, G J, Dunbar, D R, Gharbi, K, Kenyon, C J, Holmes, M C, Hardie, D G, Smith, G L & Chapman, K E 2014, ' Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes : a role for PGC-1α ', Cell Death and Differentiation . https://doi.org/10.1038/cdd.2014.181

Glucocorticoid levels rise dramatically in late gestation to mature foetal organs in readiness for postnatal life. Immature heart function may compromise survival. Cardiomyocyte glucocorticoid receptor (GR) is required for the structural and function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0f603526892466bdbe7670eaf7aa83a4
https://hdl.handle.net/20.500.11820/0d463ab0-9f7a-4540-8c70-24a96506037b

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