Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kenya Kaneko"'
Publikováno v:
Neurochemical research. 43(1)
Action potentials are fundamental to relaying information from region to region in the nervous system. Changes in action potential firing patterns in neural circuits influence how the brain processes information. In our previous study, we focused on
Autor:
Yoshihiko Yamazaki, Satoshi Fujii, Kenya Kaneko, Kenji F. Tanaka, Ming Xu, Yasukazu Hozumi, Hiroki Fujiwara, Kazuhiro Ikenaka
Publikováno v:
Glia. 62:1299-1312
Plastic changes in white matter have received considerable attention in relation to normal cognitive function and learning. Oligodendrocytes and myelin, which constitute the white matter in the central nervous system, can respond to neuronal activity
Autor:
Yoshihiko Yamazaki, Satoshi Fujii, Hiroshi Kato, Hiroshi Sasaki, Hiroki Fujiwara, Kenya Kaneko, Jianmin Li
Publikováno v:
Biomedical Research. 34:75-85
We studied the synaptic plasticity of hippocampal CA1 neurons and spatial learning behavior in gerbils that had been loaded with a transient cerebral ischemia caused by 5 min or 10 min occlusion of the bilateral carotid arteries. The stimulus thresho
Autor:
Yasukazu Hozumi, Hiroki Fujiwara, Masahiko Watanabe, Satoshi Fujii, Kaoru Goto, Matthew K. Topham, Kenya Kaneko
Publikováno v:
Cell and tissue research. 368(3)
Following activation of Gq protein-coupled receptors, phospholipase C yields a pair of second messengers: diacylglycerol (DG) and inositol 1,4,5-trisphosphate. Diacylglycerol kinase (DGK) phosphorylates DG to produce phosphatidic acid, another second
Autor:
Junichi Fujii, Mototada Shichiri, Yasukazu Yoshida, Satoshi Fujii, Junitsu Ito, Kenya Kaneko, Toshihiro Kurahashi, Yasukazu Hozumi, Mizuki Takashima, Hiroki Fujiwara, Tasuku Konno, Takujiro Homma, Kaoru Goto, Noriyuki Otsuki
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 79
Trichloroethylene (TCE) has been implicated as a causative agent for Parkinson's disease (PD). The administration of TCE to rodents induces neurotoxicity associated with dopaminergic neuron death, and evidence suggests that oxidative stress as a majo
Autor:
Koichi Furukawa, Kotaro Ikarashi, Yoshihiko Yamazaki, Kenya Kaneko, Hiroshi Sasaki, Makoto Sugita, Hiroki Fujiwara, Hiroshi Kato, Jin-ichi Inokuchi, Satoshi Fujii, Jun-Ichi Goto
Publikováno v:
Biomedical Research. 33:265-271
Gangliosides (sialic acid-containing glycosphingolipids) play important roles in many physiological functions, including synaptic plasticity in the hippocampus, which has been suggested as the basal cellular process of learning and memory in the brai
Autor:
Yoshihiko Yamazaki, Keiko Furukawa, Kotaro Ikarashi, Jun Ichi Goto, Hatsue Waki, Satoshi Fujii, Hiroshi Sasaki, Kenya Kaneko, Satoshi Fukumoto, Hiroki Fujiwara, Koichi Furukawa, Hiroshi Kato
Publikováno v:
Glycobiology. 21:1373-1381
Gangliosides (sialic acid-containing glycosphingolipids) play important roles in many physiological functions, including synaptic plasticity in the hippocampus, which is considered as a cellular mechanism of learning and memory. In the present study,
Autor:
Katsuhiko Mikoshiba, Hiroshi Kato, Satoshi Fujii, Yoshihiko Yamazaki, Masatomo Yoshioka, Kenya Kaneko
Publikováno v:
Neuroscience Research. 67:149-155
In the present study, mice lacking the type 1 inositol-1,4,5-trisphosphate receptor (IP(3)R) were used to study the role of type 1 IP(3)Rs in the induction of long-term potentiation (LTP) in hippocampal CA1 neurons. The magnitude of the LTP induced b
Autor:
Yoshihiko Yamazaki, Toshimichi Sugihara, Hiroshi Kato, Yasukazu Hozumi, Kaoru Goto, Satoshi Fujii, Kenya Kaneko
Publikováno v:
Neuron Glia Biology. 3:325-334
Like neurons and astrocytes, oligodendrocytes have a variety of neurotransmitter receptors and ion channels. However, except for facilitating the rapid conduction of action potentials by forming myelin and buffering extracellular K+, little is known
Autor:
Yuhong Jing, Eiko Sakurai, Kazuhiko Yanai, Nobuyuki Okamura, Atsuo Kuramasu, Motohisa Kato, Kenya Kaneko, Satoshi Fujii, Ajing Xu, Hiroshi Kato, Hongmei Dai
Publikováno v:
Neuroscience Research. 57:306-313
Previous pharmacological experiments provide conflicting findings that describe both facilitatory and inhibitory effects of neuronal histamine on learning and memory. Here, we examined learning and memory and synaptic plasticity in mice with a null m