Zobrazeno 1 - 10
of 557
pro vyhledávání: '"Kenton M. Sanders"'
Autor:
Sharif Amit Kamran, Hussein Moghnieh, Khondker Fariha Hossain, Allison Bartlett, Alireza Tavakkoli, Bernard T. Drumm, Kenton M. Sanders, Salah A. Baker
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39574- (2024)
Dynamic Ca2+ signaling is crucial for cell survival and death, and Ca2+ imaging approaches are commonly used to study and measure cellular Ca2+ patterns within cells. However, the presence of image noise from instrumentation and experimentation proto
Externí odkaz:
https://doaj.org/article/6b58be84b756423d8cae8f266c925f39
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Protease-activated receptor-1 (PAR1) is highly expressed in murine colonic smooth muscles. Responses to PAR1 activation are complex and result from responses in multiple cell types. We investigated whether PAR1 responses are altered in infla
Externí odkaz:
https://doaj.org/article/4004c89198b04868adc8bee07b8f81b3
Autor:
Haeyeong Lee, Byoung H. Koh, Lauren E. Peri, Holly J. Woodward, Brian A. Perrino, Kenton M. Sanders, Sang Don Koh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα+) cells h
Externí odkaz:
https://doaj.org/article/2fec9f31909a46bb9ff04c8c8358e0b1
Autor:
Ken Lee, Sang O Park, Pil-Cho Choi, Seung-Bum Ryoo, Haeyeong Lee, Lauren E. Peri, Tong Zhou, Robert D. Corrigan, Andrew C. Yanez, Suk B. Moon, Brian A. Perrino, Kenton M. Sanders, Sang Don Koh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Volume accommodation occurs via a novel mechanism involving interstitial cells in detrusor muscles. The interstitial cells in the bladder are PDGFRα+, and they restrain the excitability of smooth muscle at low levels and prevents the develo
Externí odkaz:
https://doaj.org/article/2ffc5cafa1a74f33afd2860ded277ffe
Autor:
Sharif Amit Kamran, Khondker Fariha Hossain, Hussein Moghnieh, Sarah Riar, Allison Bartlett, Alireza Tavakkoli, Kenton M. Sanders, Salah A. Baker
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104277- (2022)
Summary: Cellular imaging instrumentation advancements as well as readily available optogenetic and fluorescence sensors have yielded a profound need for fast, accurate, and standardized analysis. Deep-learning architectures have revolutionized the f
Externí odkaz:
https://doaj.org/article/027dffd29916407e90ab7b1ba352f3e8
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 233-240 (2020)
BACKGROUND: Alpha-type platelet-derived growth factor receptor (PDGFRα) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRα plays an important role in the regulation of several biological proc
Externí odkaz:
https://doaj.org/article/f443235366d84fbb9f7fef65c094a7b3
Autor:
Se Eun Ha, Byungchang Jin, Brian G. Jorgensen, Hannah Zogg, Lai Wei, Rajan Singh, Chanjae Park, Masaaki Kurahashi, Sei Kim, Gain Baek, Sandra M. Poudrier, Moon Young Lee, Kenton M. Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Subepithelial platelet-derived growth factor receptor alpha (PDGFRα)+ cells found in the colonic mucosal tissue come in close contact with epithelial cells, immune cells, neurons, capillaries, and lymphatic networks. Mucosal subepithelial PDGFRα+ c
Externí odkaz:
https://doaj.org/article/e0ce6f5c5dfc4d18818052ef84064da0
Autor:
Alejandro Gutierrez Cruz, Mafalda S. L. Aresta Branco, Brian A. Perrino, Kenton M. Sanders, Violeta N. Mutafova-Yambolieva
Publikováno v:
Metabolites, Vol 13, Iss 1, p 30 (2022)
Adenosine 5′-triphosphate (ATP) is released in the bladder lumen during filling. Urothelial ATP is presumed to regulate bladder excitability. Urinary ATP is suggested as a urinary biomarker of bladder dysfunctions since ATP is increased in the urin
Externí odkaz:
https://doaj.org/article/b83f19e5c3b2449d8bd49bb35ce64f74
Autor:
Haifeng Zheng, Bernard T. Drumm, Mei Hong Zhu, Yeming Xie, Kate E. O'Driscoll, Salah A. Baker, Brian A. Perrino, Sang Don Koh, Kenton M. Sanders
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/99cbcf3029a94b51933e5b28c45d8793
Autor:
Haifeng Zheng, Bernard T. Drumm, Mei Hong Zhu, Yeming Xie, Kate E. O’Driscoll, Salah A. Baker, Brian A. Perrino, Sang Don Koh, Kenton M. Sanders
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Interstitial cells of Cajal (ICC) are pacemaker cells that generate electrical slow waves in gastrointestinal (GI) smooth muscles. Slow waves organize basic motor patterns, such as peristalsis and segmentation in the GI tract. Slow waves depend upon
Externí odkaz:
https://doaj.org/article/e4bfb74ddf7a4fa28f3b24effc9b71b8