Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kenton Longenecker"'
Autor:
Qi Hao, Manoj K. Rathinaswamy, Kelly L. Klinge, Matthew Bratkowski, Amirhossein Mafi, Christina K. Baumgartner, Keith M. Hamel, Gesine K. Veits, Rinku Jain, Claudio Catalano, Mark Fitzgerald, Alexander W. Hird, Eunice Park, Harit U. Vora, James A. Henderson, Kenton Longenecker, Charles W. Hutchins, Wei Qiu, Giovanna Scapin, Qi Sun, Vincent S. Stoll, Chaohong Sun, Ping Li, Dan Eaton, David Stokoe, Stewart L. Fisher, Christopher G. Nasveschuk, Marcia Paddock, Michael E. Kort
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract PTPN2 (protein tyrosine phosphatase non-receptor type 2, or TC-PTP) and PTPN1 are attractive immuno-oncology targets, with the deletion of Ptpn1 and Ptpn2 improving response to immunotherapy in disease models. Targeted protein degradation ha
Externí odkaz:
https://doaj.org/article/1f2680b79836478cba894b08e1a585a6
Autor:
Wei Qiu, Qi Sun, Yi Yang, Chirag Patel, Meng Sun, Yue Liu, Kyle Halliwill, Sarah Kim, Rebecca Mathew, Jennifer M Frost, Jennifer A Roth, Domenick Kennedy, Robert T Manguso, Kathleen B Yates, Hakimeh Ebrahimi-Nik, Christina K Baumgartner, Arvin Iracheta-Vellve, Keith M Hamel, Kira Olander, Thomas GR Davis, Kathleen A McGuire, Geoff T Halvorsen, Omar I Avila, Ashwin V Kammula, Audrey J Muscato, Prasanthi Geda, Kelly Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D Yeary, James C Patti, Tyler M Balon, Carey Backus, Angeline Chen, Kenton Longenecker, Joseph Klahn, Cara Hrusch, Navasona Krishnan, Charles W Hutchins, Jacqueline Aguado, Marinka Bulic, Payal Tiwari, Kayla J Colvin, Cun Lan Chuong, Ian C Kohnle, Matthew G Rees, Andrew Boghossian, Melissa Ronan, Meng-Ju Wu, Debattama R Sen, Gabriel K Griffin, Nabeel El-Bardeesy, Patricia Trusk, Joshua H Decker, Stacey Fossey, Marcia N Paddock, Elliot P Farney, Clay Beauregard, Philip R Kym
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/11356ff1bf1f4b63ab1324cafa253315
Autor:
George S, Sheppard, Le, Wang, Steven D, Fidanze, Lisa A, Hasvold, Dachun, Liu, John K, Pratt, Chang H, Park, Kenton, Longenecker, Wei, Qiu, Maricel, Torrent, Peter J, Kovar, Mai, Bui, Emily, Faivre, Xiaoli, Huang, Xiaoyu, Lin, Denise, Wilcox, Lu, Zhang, Yu, Shen, Daniel H, Albert, Terrance J, Magoc, Ganesh, Rajaraman, Warren M, Kati, Keith F, McDaniel
Publikováno v:
Journal of medicinal chemistry. 63(10)
The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under clinical development for oncology bind to each of the eight bromodomains with si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::283055280d03954bedb827a07dda077b
https://pubmed.ncbi.nlm.nih.gov/32324999
https://pubmed.ncbi.nlm.nih.gov/32324999
Autor:
Hao, Qi1 qhao@calicolabs.com, Rathinaswamy, Manoj K.1, Klinge, Kelly L.2, Bratkowski, Matthew1, Mafi, Amirhossein1, Baumgartner, Christina K.2, Hamel, Keith M.2, Veits, Gesine K.3, Jain, Rinku2, Catalano, Claudio4, Fitzgerald, Mark3, Hird, Alexander W.3, Park, Eunice3, Vora, Harit U.3, Henderson, James A.3, Longenecker, Kenton2, Hutchins, Charles W.2, Qiu, Wei2, Scapin, Giovanna4, Sun, Qi2
Publikováno v:
Communications Chemistry. 8/16/2024, Vol. 7 Issue 1, p1-16. 16p.
Publikováno v:
RSC Medicinal Chemistry; Mar2024, Vol. 15 Issue 3, p761-768, 8p
Autor:
Zhonghua Pei, Xiaofeng Li, Thomas W. von Geldern, Kenton Longenecker, Daisy Pireh, Kent D. Stewart, Bradley J. Backes, Chunqiu Lai, Thomas H. Lubben, Stephen J. Ballaron, David W. A. Beno, Anita J. Kempf-Grote, Hing L. Sham, James M. Trevillyan
Publikováno v:
Journal of Medicinal Chemistry; Apr2007, Vol. 50 Issue 8, p1983-1987, 5p
Publikováno v:
RSC Medicinal Chemistry; Mar2024, Vol. 15 Issue 3, p832-838, 7p
Autor:
Upadhyay, Anup K.1, Cyr, Matthew1, Longenecker, Kenton1, Tripathi, Rakesh1, Sun, Chaohong1, Kempf, Dale J.1
Publikováno v:
Acta Crystallographica: Section F, Structural Biology Communications. Mar2017, Vol. 73 Issue 3, p116-122. 6p.
Autor:
Loberg, Lise I., Chhaya, Meha, Ibraghimov, Alexander, Tarcsa, Edit, Striebinger, Andreas, Popp, Andreas, Huang, Lili, Oellien, Frank, Barghorn, Stefan
Publikováno v:
mAbs; Jan-Dec 2021, Vol. 13 Issue 1, p1-13, 13p
Autor:
Faivre, Emily J., McDaniel, Keith F., Albert, Daniel H., Mantena, Srinivasa R., Plotnik, Joshua P., Wilcox, Denise, Zhang, Lu, Bui, Mai H., Sheppard, George S., Wang, Le, Sehgal, Vasudha, Lin, Xiaoyu, Huang, Xiaoli, Lu, Xin, Uziel, Tamar, Hessler, Paul, Lam, Lloyd T., Bellin, Richard J., Mehta, Gaurav, Fidanze, Steve
Publikováno v:
Nature; 2/13/2020, Vol. 578 Issue 7794, p306-310, 5p, 1 Diagram, 3 Charts, 10 Graphs