Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kento Tazawa"'
Autor:
Shihan Wang, Nobuyuki Kawashima, Peifeng Han, Keisuke Sunada-Nara, Ziniu Yu, Kento Tazawa, Mayuko Fujii, Thoai Quoc Kieu, Takashi Okiji
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9694 (2024)
MicroRNA-27a-5p (miR-27a-5p) was significantly upregulated in dental pulp inflammation, yet its underlying mechanisms remain unclear. This study investigated the effect of miR-27a-5p on the expression of proinflammatory cytokines in human dental pulp
Externí odkaz:
https://doaj.org/article/731be8bebe004384865775f8fa2116de
Autor:
Kento Tazawa, Rutuja Jadhav, Mariane Maffei Azuma, J. Christopher Fenno, Neville J. McDonald, Hajime Sasaki
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Droplets and aerosols produced during dental procedures are a risk factor for microbial and viral transmission. Unlike sodium hypochlorite, hypochlorous acid (HOCl) is nontoxic to tissues but still exhibits broad microbicidal effe
Externí odkaz:
https://doaj.org/article/87866a7c892b47a7ae14088f8bed123e
Autor:
Thoai Quoc Kieu, Kento Tazawa, Nobuyuki Kawashima, Sonoko Noda, Mayuko Fujii, Keisuke Nara, Kentaro Hashimoto, Peifeng Han, Takashi Okiji
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Tissue-resident macrophages expressing lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) are found in multiple tissues and organs. We aimed to evaluate the dynamics and biological functions of LYVE-1+ macrophages in dental pulp dur
Externí odkaz:
https://doaj.org/article/e785b702e5b54909a4293f239fa80d98
Autor:
Shion Orikasa, Nobuyuki Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Sunada-Nara, Sonoko Noda, Mayuko Fujii, Tetsu Akiyama, Takashi Okiji
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Accelerated dental pulp mineralization is a common complication in avulsed/luxated teeth, although the mechanisms underlying this remain unclear. We hypothesized that hypoxia due to vascular severance may induce osteo/odontoblast differentia
Externí odkaz:
https://doaj.org/article/414bc6540fbb49f5a730bc042ccaddc8
Publikováno v:
Frontiers in Dental Medicine, Vol 3 (2022)
Apical periodontitis (AP) develops as a result of an immune response to pulpal bacterial infection, and various cytokines are involved in the pathogenesis of AP, with Interleukin (IL)-1 being considered a key cytokine. The role of IL-1 in the pathoge
Externí odkaz:
https://doaj.org/article/ae201b4e031b40449a95df58b18dd44d
Publikováno v:
Frontiers in Dental Medicine; 2024, p01-09, 9p
Autor:
Kento Tazawa, Hajime Sasaki
Publikováno v:
Journal of oral biosciences.
Apical periodontitis is an inflammatory disease involving lesions located within the jawbone. Histological evaluations generally require decalcification and sectioning, which has limited our understanding of the three-dimensional (3D) organization an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44888c4a92cd101930c442ab2bb9646
https://pubmed.ncbi.nlm.nih.gov/36587735
https://pubmed.ncbi.nlm.nih.gov/36587735
Autor:
Takashi Okiji, Masashi Kuramoto, Keisuke Nara, Kento Tazawa, Nobuyuki Kawashima, Sonoko Noda, Kentaro Hashimoto, Mayuko Fujii
Publikováno v:
The American Journal of Pathology. 190:2417-2426
Increased expression of the transient receptor potential ankyrin 1 (TRPA1) channel has been detected in carious tooth pulp, suggesting involvement of TRPA1 in defense or repair of this tissue after exogenous noxious stimuli. This study aimed to eluci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3f8c3d6c35f3cb7be13bfd7262d352
https://doi.org/10.1016/j.ajpath.2020.08.016
https://doi.org/10.1016/j.ajpath.2020.08.016
Autor:
Shion Orikasa, Takashi Okiji, Sonoko Noda, Nobuyuki Kawashima, Keisuke Nara, Kentaro Hashimoto, Masashi Kuramoto, Shigenori Nagai, Mayuko Fujii, Kento Tazawa
Publikováno v:
Biochemical and Biophysical Research Communications. 522:308-314
Hypoxia-inducible factor 1 alpha (HIF1α) is a transcriptional factor that plays a key role in the regulation of various molecules expressed in hypoxic conditions. Ischemic/hypoxic conditions are regarded as a distinct characteristic of dental pulp i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b271d1a1e11db0f91519ec0b92f777f1
https://doi.org/10.1016/j.bbrc.2019.11.032
https://doi.org/10.1016/j.bbrc.2019.11.032
Autor:
Kento Tazawa, Mayuko Fujii, Takashi Okiji, Keisuke Nara, Kentaro Hashimoto, Sonoko Noda, Nobuyuki Kawashima
Publikováno v:
Journal of Cellular Physiology. 234:21331-21341
microRNAs are small noncoding RNA molecules that regulate RNA silencing and posttranscriptional gene expression, and many microRNAs are involved in inflammatory processes. In particular, microRNA 21 (miR-21) is upregulated in inflammatory environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbd6374473d19edbcc1e84551e4d714
https://doi.org/10.1002/jcp.28737
https://doi.org/10.1002/jcp.28737