Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kento TAKAYAMA"'
Autor:
Shoji Maehara, Shogo Nakajima, Koichi Watashi, Andria Agusta, Misato Kikuchi, Toshiyuki Hata, Kento Takayama
Publikováno v:
Journal of Fungi, Vol 9, Iss 9, p 905 (2023)
Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic agents for the disease are being developed. Endophytes are diverse and produce various secondary metabolites and bioactive substances. We
Externí odkaz:
https://doaj.org/article/9be49459aea14f49a98fb1357d50022f
Autor:
Hirofumi Inoue, Nobuyuki Okamura, Yuuko Date, Kento Takayama, Norihiko Tabuchi, Naoko Narahara, Yasuto Tsuruta, Chiho Takahara, Eijiro Kojima
Publikováno v:
Biological and Pharmaceutical Bulletin. 42:845-849
It has been suggested that imbalances in gut microbiota are related to diseases associated with metabolism, the central nervous system, etc. Therefore, analysis of short-chain fatty acids (SCFAs) produced by gut microbiota is very important as an ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65817f8a2887c8b0eb44ac2621018561
https://doi.org/10.1248/bpb.b18-01017
https://doi.org/10.1248/bpb.b18-01017
Publikováno v:
Journal of natural medicines. 75(1)
Indole is produced from dietary tryptophan by tryptophanase in intestinal bacteria, such as Escherichia coli. In the liver, indole is converted into indoxyl sulfate, a uremic toxin and risk factor for chronic kidney disease (CKD). Probiotics and preb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94dffb6b2a55d7c7fb71ea79f6be42f
https://pubmed.ncbi.nlm.nih.gov/33078328
https://pubmed.ncbi.nlm.nih.gov/33078328
Publikováno v:
The Proceedings of The Computational Mechanics Conference. :140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82cd5c2a246529db76fccedffb314768
https://doi.org/10.1299/jsmecmd.2021.34.140
https://doi.org/10.1299/jsmecmd.2021.34.140
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:378-383
Sennoside A (SA), the main purgative constituent of Daiokanzoto (da-huang-gan-cao-tang; DKT), is generally regarded as a prodrug that is transformed into an active metabolite by β-glucosidase derived from Bifidobacterium spp. It has been suggested t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f772c9762115acc6cff430b6b4bb9533
https://doi.org/10.1248/bpb.b15-00815
https://doi.org/10.1248/bpb.b15-00815
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Interindividual differences affect the purgative activities of sennoside A (SA) and Daiokanzoto (Da-Huang-Gan-Cao-Tang, DKT). In this study, we manipulated gut microbiota in mice to establish laxative responders and non-responders by feeding them a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a2482cb27f5543ce871d5b4ac47529
https://pubmed.ncbi.nlm.nih.gov/30846728
https://pubmed.ncbi.nlm.nih.gov/30846728
Publikováno v:
The Proceedings of the Materials and Mechanics Conference. 2019:OS0719
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe66891f322c04dddee9df8e3394634b
https://doi.org/10.1299/jsmemm.2019.os0719
https://doi.org/10.1299/jsmemm.2019.os0719
Publikováno v:
Biologicalpharmaceutical bulletin. 39(3)
Sennoside A (SA), the main purgative constituent of Daiokanzoto (da-huang-gan-cao-tang; DKT), is generally regarded as a prodrug that is transformed into an active metabolite by β-glucosidase derived from Bifidobacterium spp. It has been suggested t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b9617f6ec1cc11aa3a30dae74279bb4
https://pubmed.ncbi.nlm.nih.gov/26934929
https://pubmed.ncbi.nlm.nih.gov/26934929
Publikováno v:
Biological and Pharmaceutical Bulletin. 35:2204-2208
Rhubarb is one of the most well-known herbal medicines that constitute daiokanzoto (DKT), which is clinically effective for constipation. Sennoside A is transformed into an active metabolite, rheinanthrone, by intestinal bacteria. Sennoside A in rhub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91c1db9555bc755a128d2bd62203da5
https://doi.org/10.1248/bpb.b12-00632
https://doi.org/10.1248/bpb.b12-00632
Autor:
Nobuyuki Okamura, Emi Matsui, Kento Takayama, Takeshi Kobayashi, Yasuto Tsuruta, Hirofumi Inoue
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:1106-1109
Daiokanzoto (DKT, combination of rhubarb and glycyrrhiza), a Kampo medicine, is clinically effective for constipation. Sennoside A is well known to induce diarrhea. Sennoside A is a prodrug that is transformed into an active metabolite, rheinanthrone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d374539323c723b83b7c3321fed5ddb3
https://doi.org/10.1248/cpb.59.1106
https://doi.org/10.1248/cpb.59.1106