Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kento Onishi"'
Autor:
Ayako Yachie‐Kinoshita, Kento Onishi, Joel Ostblom, Matthew A Langley, Eszter Posfai, Janet Rossant, Peter W Zandstra
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 1, Pp 1-16 (2018)
Abstract Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular properties and molecular signatures. The mechanisms that maintain pluripotency, or that cause its destabilization to initiate development, are complex
Externí odkaz:
https://doaj.org/article/636e86fc8cc5407ea6b8435720f6b893
Publikováno v:
Stem Cell Reports, Vol 3, Iss 1, Pp 156-168 (2014)
Conversion of EpiSCs to naive ESCs is a rare event that is driven by the reestablishment of the naive transcription factor network. In mice, STAT3 activation is sufficient to drive conversion of EpiSCs to the naive pluripotent stem cell (PSC) state.
Externí odkaz:
https://doaj.org/article/92e2a5f7ced64f3195a905f2b5e97880
Autor:
Brian DeVeale, Irina Brokhman, Paria Mohseni, Tomas Babak, Charles Yoon, Anthony Lin, Kento Onishi, Alexey Tomilin, Larysa Pevny, Peter W Zandstra, Andras Nagy, Derek van der Kooy
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003957 (2013)
Oct4 is a widely recognized pluripotency factor as it maintains Embryonic Stem (ES) cells in a pluripotent state, and, in vivo, prevents the inner cell mass (ICM) in murine embryos from differentiating into trophectoderm. However, its function in som
Externí odkaz:
https://doaj.org/article/78f41e00bb37438884efa63e55559052
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6438 (2009)
In vivo, stem cell fate is regulated by local microenvironmental parameters. Governing parameters in this stem cell niche include soluble factors, extra-cellular matrix, and cell-cell interactions. The complexity of this in vivo niche limits analyses
Externí odkaz:
https://doaj.org/article/7ef4dd2dfc4448c99f8859bb2d8dce86
Publikováno v:
The Proceedings of Conference of Chugoku-Shikoku Branch. :08c3
Publikováno v:
The Proceedings of Conference of Chugoku-Shikoku Branch. :08c2
Publikováno v:
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY. 32:240-243
Autor:
Peter W. Zandstra, Kento Onishi, Joel Ostblom, Janet Rossant, Ayako Yachie-Kinoshita, Eszter Posfai, Matthew A Langley
Publikováno v:
Molecular Systems Biology
Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular properties and molecular signatures. The mechanisms that maintain pluripotency, or that cause its destabilization to initiate development, are complex and inco
Autor:
Yutaka Kofuku, Takumi Ueda, Junya Okude, Takuya Mizumura, Naoyuki Nobuyama, Motohiko Sato, Keita Kondo, Mei Natsume, Kento Onishi, Masahiro Maeda, Yutaro Shiraishi, Masayuki Inoue, Hideki Tsujishita, Takefumi Kuranaga, Ichio Shimada
Publikováno v:
Angewandte Chemie (International Ed. in English)
G-protein-coupled receptor (GPCR) ligands impart differing degrees of signaling in the G-protein and arrestin pathways, in phenomena called “biased signaling”. However, the mechanism underlying the biased signaling of GPCRs is still unclear, alth
Publikováno v:
Volume 5: High-Pressure Technology; ASME Nondestructive Evaluation, Diagnosis and Prognosis Division (NDPD); SPC Track for Senate.
Desktop vibration isolators are often used as precision measuring instruments. This article discusses the accuracy of performance prediction methods for vibration isolators elastically supported by four air springs. Each air spring possesses a reserv