Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kento Ojima"'
Autor:
Kento Ojima, Wataru Kakegawa, Tokiwa Yamasaki, Yuta Miura, Masayuki Itoh, Yukiko Michibata, Ryou Kubota, Tomohiro Doura, Eriko Miura, Hiroshi Nonaka, Seiya Mizuno, Satoru Takahashi, Michisuke Yuzaki, Itaru Hamachi, Shigeki Kiyonaka
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Cell-type-specific activation of receptors is desirable for elucidating their roles in tissues or animals. Here, the authors developed a chemogenetic method for direct activation of mGlu1, a GPCR-type glutamate receptor subtype, and demonstrate its u
Externí odkaz:
https://doaj.org/article/cd76cfd6d6cb4625a26a3214108f2c32
Autor:
Kento Ojima, Kazuki Shiraiwa, Kyohei Soga, Tomohiro Doura, Mikiko Takato, Kazuhiro Komatsu, Michisuke Yuzaki, Itaru Hamachi, Shigeki Kiyonaka
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The analysis of AMPA-type glutamate receptor (AMPAR) trafficking is essential for understanding molecular mechanisms of learning and memory, but the analytical tools are currently limited. Here, the authors report a method that combines affinity-base
Externí odkaz:
https://doaj.org/article/738bc8a87bde4b819f6d2abb0650a08c
Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
Cell-surface receptors play a pivotal role as transducers of extracellular input. Although different cell types express the same receptor, the physiological roles of the receptor are highly dependent on cell type. To understand each role, tactics for
Externí odkaz:
https://doaj.org/article/306bc12b7b1f4ed3af5b57914f996193
Publikováno v:
ACS Central Science, Vol 4, Iss 9, Pp 1211-1221 (2018)
Externí odkaz:
https://doaj.org/article/4703ffa9e2444b6eb1688fd261a5028e
Publikováno v:
Folia Pharmacologica Japonica. 157:191-195
Glutamate receptors mediate excitatory neurotransmission in the central nervous system, which have essential roles in our learning and memory. Recent studies have revealed that the trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a39fc06da0087216c3a5f257f8e5f8
https://doi.org/10.1254/fpj.22002
https://doi.org/10.1254/fpj.22002
Autor:
KAHO MATSUMURA, AKIHIRO INOUE, AKARI MIKI, KENTO OJIMA, TOMOSUKE SATO, HIROMI WATANABE, AKIKO KOMURA, MIZUKI TADOKORO, AKIFUMI KAWATA, YUKIO MURAKAMI
Publikováno v:
Japanese Journal of Oral Diagnosis / Oral Medicine. 35:131-134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de35df60f51610f023538b7da550659a
https://doi.org/10.15214/jsodom.35.131
https://doi.org/10.15214/jsodom.35.131
Publikováno v:
Folia Pharmacologica Japonica. 157:366-370
Transmembrane receptors transmit extracellular information into cells. In many cases, protein families are composed of highly homologous subtypes, each of which has unique cellular functions. Therefore, it is highly desired for understanding the phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaade9b3660c27d559de39a842c7cfb0
https://doi.org/10.1254/fpj.22047
https://doi.org/10.1254/fpj.22047
Autor:
Kazuhiro Komatsu, Mikiko Takato, Kento Ojima, Tomohiro Doura, Kazuki Shiraiwa, Shigeki Kiyonaka, Michisuke Yuzaki, Itaru Hamachi, Kyohei Soga
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
The regulation of glutamate receptor localization is critical for development and synaptic plasticity in the central nervous system. Conventional biochemical and molecular biological approaches have been widely used to analyze glutamate receptor traf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef5f285ee99c979a2ea7ed5d7603feb
https://doaj.org/article/738bc8a87bde4b819f6d2abb0650a08c
https://doaj.org/article/738bc8a87bde4b819f6d2abb0650a08c
Cell-surface receptors play a pivotal role as transducers of extracellular input. Although different cell types express the same receptor, the physiological roles of the receptor are highly dependent on cell type. To understand each role, tactics for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17f73948dd6e4185e5d5ebf4dd2d9b28
https://doi.org/10.26434/chemrxiv-2021-nxbn4
https://doi.org/10.26434/chemrxiv-2021-nxbn4
Autor:
Kento Ojima, Wataru Kakegawa, Tokiwa Yamasaki, Yuta Miura, Masayuki Itoh, Yukiko Michibata, Ryou Kubota, Tomohiro Doura, Eriko Miura, Hiroshi Nonaka, Seiya Mizuno, Satoru Takahashi, Michisuke Yuzaki, Itaru Hamachi, Shigeki Kiyonaka
Publikováno v:
Nature communications. 13(1)
Direct activation of cell-surface receptors is highly desirable for elucidating their physiological roles. A potential approach for cell-type-specific activation of a receptor subtype is chemogenetics, in which both point mutagenesis of the receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71228d2bb06e10c3f8b2c09aee36569
https://pubmed.ncbi.nlm.nih.gov/35710788
https://pubmed.ncbi.nlm.nih.gov/35710788