Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Kento, Yoshioka"'
Autor:
Keyue Xu, Miyuki Shimizu, Toma Yamashita, Mako Fujiwara, Shunya Oikawa, Guanghan Ou, Naho Takazakura, Taichi Kusakabe, Keisuke Takahashi, Keisuke Kato, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract We studied the inhibitory actions of docosahexaenoic acid (DHA) on the contractions induced by carbachol (CCh), angiotensin II (Ang II), and bradykinin (BK) in guinea pig (GP) gastric fundus smooth muscle (GFSM), particularly focusing on the
Externí odkaz:
https://doaj.org/article/841d30230a424536a7c329e8b7221e49
Autor:
Guanghan Ou, Akane Komura, Misaki Hojo, Rina Kato, Masahiro Ikeda, Miki Fujisawa, Keyue Xu, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Publikováno v:
Journal of Pharmacological Sciences, Vol 153, Iss 3, Pp 119-129 (2023)
We examined whether U46619 (a prostanoid TP receptor agonist) could enhance the contractions of guinea pig urinary bladder smooth muscle (UBSM) in response to acetylcholine (ACh) and an ATP analog (α,β-methylene ATP (αβ-MeATP)) through stimulatio
Externí odkaz:
https://doaj.org/article/399fcfd3f8a14d0ab0732f60693196b4
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 2, Pp 123-127 (2023)
We investigated the extracellular Ca2+ influx pathways involved in platelet-activating factor (PAF)-enhanced guinea pig detrusor smooth muscle (DSM) contractile activities. One micromolar PAF-enhanced DSM contractile activities were completely inhibi
Externí odkaz:
https://doaj.org/article/242bc75c9e154105a529975958df74e2
Autor:
Kento Yoshioka, Keisuke Obara, Shunya Oikawa, Kohei Uemura, Akina Yamaguchi, Kazuki Fujisawa, Hitomi Hanazawa, Miki Fujiwara, Taison Endoh, Taichi Suzuki, Montserrat De Dios Regadera, Daichi Ito, Noboru Saitoh, Yutaka Nakagome, Toma Yamashita, Mayu Kiguchi, Yuka Saito, Yuri Nakao, Hinako Miyaji, Guanghan Ou, Keyue Xu, Yoshio Tanaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract This study was performed to elucidate whether eicosapentaenoic acid (EPA) suppresses spasm-prone blood vessel contractions induced by a thromboxane mimetic (U46619) and prostaglandin F2α (PGF2α) and determine whether the primary target of
Externí odkaz:
https://doaj.org/article/10857a2eae444486b3a4c1d213f72d59
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In this study, we investigated the effects of platelet-activating factor (PAF) on the basal tone and spontaneous contractile activities of guinea pig (GP) and mouse urinary bladder (UB) smooth muscle (UBSM) tissues to determine whether PAF c
Externí odkaz:
https://doaj.org/article/f1c16a5b42314053914c39ea5fa42a69
Autor:
Keyue Xu, Miyuki Shimizu, Chika Murai, Miki Fujisawa, Daichi Ito, Noboru Saitoh, Yutaka Nakagome, Mio Yamashita, Azusa Murata, Shunya Oikawa, Guanghan Ou, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract The inhibitory effects of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and linoleic acid (LA) on the contractions induced by five prostanoids and U46619 (a TP receptor agonist) were examined in guinea pig gastric fundus smooth mu
Externí odkaz:
https://doaj.org/article/f72ed198a11f44b28d567848e7428224
Autor:
Keisuke Obara, Yuka Matsuoka, Naoya Iwata, Yukako Abe, Yohei Ikegami, Ayano Fujii, Kento Yoshioka, Yoshio Tanaka
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:354-358
Autor:
Keisuke Obara, Kento Yoshioka, Montserrat De Dios Regadera, Yusuke Matsuyama, Ayano Yashiro, Mayumi Miyokawa, Rumi Iura, Yoshio Tanaka
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:309-319
Autor:
Keisuke Obara, Rikako Inaba, Mirai Kawakita, Montserrat De Dios Regadera, Tomomi Uetake, Azusa Murata, Nanako Nishioka, Kota Kuroki, Kento Yoshioka, Yoshio Tanaka
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:240-244
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 437-444 (2015)
Neural stem cells (NSC) from the adult hippocampus easily lose their activityin vitro. Efficientin vitro expansion of adult hippocampus‐derived NSC is important for generation of tools for research and cell therapy. Here, we show that a single copy
Externí odkaz:
https://doaj.org/article/e1f34e0b160a42afa2ede7d333c42c9c