Výsledky vyhledávání - "Kentarou Naruchi"

Unexpected Tolerance of Glycosylation by UDP-GalNAc:Polypeptide α-N-Acetylgalactosaminyltransferase Revealed by Electron Capture Dissociation Mass Spectrometry: Carbohydrate as Potential Protective Groups

Autor: Kentarou Naruchi, Haruhiko Fujihira, Takahiko Matsushita, Yasuhiro Takegawa, Shin-Ichiro Nishimura, Hiroshi Hinou, Yayoi Yoshimura, Naoki Fujitani, Kentaro Kato, Xiao-Dong Gao, Takeshi Sakamoto, Naomi Manri

Publikováno v: Biochemistry. 49:5929-5941

UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases (ppGalNAcTs, EC 2.4.1.41), a family of key enzymes that initiate posttranslational modification with O-glycans in mucin synthesis by introduction of alpha-GalNAc residues, are structural

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fd580f5098c2320d6265b0f2b3e9e0
https://doi.org/10.1021/bi100623g

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Functional Neoglycopeptides: Synthesis and Characterization of a New Class of MUC1 Glycoprotein Models Having Core 2-Based O-Glycan and Complex-Type N-Glycan Chains

Autor: Shin-Ichiro Nishimura, Hiroshi Takemoto, Hiroki Shimizu, Masataka Fumoto, Takeshi Sakamoto, Hideki Nakata, Masaki Kurogochi, Takaomi Ito, Reiko Sadamoto, Hiroko Togame, Takahiko Matsushita, Naoki Ohyabu, Naoki Fujitani, Kentarou Naruchi, Hirosato Kondo, Yasuhiro Takegawa, Hiroshi Hinou

Publikováno v: Biochemistry. 48:11117-11133

An efficient protocol for the construction of MUC1-related glycopeptide analogues having complex O-glycan and N-glycan chains was established by integrating chemical and enzymatic approaches on the functional polymer platforms. We demonstrated the fe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f12dd8927c4076b414ea6389ea05cb
https://doi.org/10.1021/bi901557a

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Synthesis of a 3,4-Di-O-substituted Heptose Structure: A Partial Oligosaccharide Expressed in Neisserial Lipooligosaccharide

Autor: Kentarou Naruchi, Hiroyuki Koshino, Ryohei Yamasaki, Hiroyuki Kubo, Kazuyuki Ishii, Kenji Toubetto

Publikováno v: European Journal of Organic Chemistry. 2004:1202-1213

We have synthesized a tetrasaccharide containing a 3,4-dibranched L-glycero-D-manno-heptose (Hep), β-lactosyl-(1⇄4)-[L-α-D-Hep-(1⇄3)]-L-α-D-Hep 19, by using a mannose (Man) derivative as an acceptor. Prior to the construction of the branched H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd01f562171046e0cc31bca8df900605
https://doi.org/10.1002/ejoc.200300651

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Construction and Structural Characterization of Versatile Lactosaminoglycan-Related Compound Library for the Synthesis of Complex Glycopeptides and Glycosphingolipids

Autor: Naoki Fujitani, Takahiko Matsushita, Kentarou Naruchi, Shin-Ichiro Nishimura, Hirosato Kondo, Tomoki Hamamoto, Hiroshi Hinou, Masaki Kurogochi, Hiroki Shimizu

Publikováno v: ChemInform. 38

We have established a facile and efficient protocol for the preparative-scale synthesis of various compound libraries related to lactosaminoglycans: cell surface oligosaccharides composed of N-acetyllactosamine as a repeating disaccharide unit, based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d1ab01ff2dee03dddc6f8395f23441
https://doi.org/10.1002/chin.200714203

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Akademický článek

Synthesis of a 3,4-Di-O-substituted Heptose Structure: A Partial Oligosaccharide Expressed in Neisserial Lipooligosaccharide.

Autor: Hiroyuki Kubo, Kazuyuki Ishii, Hiroyuki Koshino, Kenji Toubetto, Kentarou Naruchi, Ryohei Yamasaki

Publikováno v: European Journal of Organic Chemistry; Mar2004, Vol. 2004 Issue 6, p1202-1213, 12p

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