Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kentaro Wakayama"'
Autor:
Alexander J. Pfeil, Joshua D. Hale, Tiger S. Zhang, Kentaro Wakayama, Isao Miyazaki, Igor Odintsov, Romel Somwar
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/0d92640ece314fcb848e30d2f5bed130
Autor:
Igor Odintsov, Allan J.W. Lui, Kota Ishizawa, Isao Miyazaki, Inna Khodos, Kentaro Wakayama, Morana Vojnic, Connor J. Hagen, Qing Chang, Annalisa Bonifacio, Claudio Giuliano, Elisa de Stanchina, Emanuela Lovati, Emily Cheng, Marc Ladanyi, Romel Somwar
Publikováno v:
Journal of Clinical Oncology. 40:2024-2024
2024 Background: Patients with RET fusion-positive NSCLC have an estimated 25% incidence of CNS metastasis at diagnosis, and up to 40% during disease progression. Effective anti-RET therapy that penetrates the blood-brain barrier is essential to exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d992c2cf183e7fb84bbf233106d83b8f
https://doi.org/10.1200/jco.2022.40.16_suppl.2024
https://doi.org/10.1200/jco.2022.40.16_suppl.2024
Autor:
Yasuo Uchida, Kentaro Wakayama, Yasuyuki Ishii, Tomoyuki Ohe, Tetsuya Terasaki, Masato Chiba, Sumio Ohtsuki
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 350:578-588
The aim of this study was to investigate whether in vivo drug distribution in brain in monkeys can be reconstructed by integrating four factors: protein expression levels of P-glycoprotein (P-gp)/multidrug resistance protein 1 at the blood-brain barr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7366df0f22fb02c77831e96b984a52db
https://doi.org/10.1124/jpet.114.214536
https://doi.org/10.1124/jpet.114.214536
Publikováno v:
Neuroscience Research. 44:173-180
Monoamines function as a vasoactive modulator in the central nervous system (CNS) and are believed to regulate blood-brain barrier (BBB) function. Although monoamine transport is an essential process for regulating the extracellular monoamine concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab63e9a50d23a2caaafcbe33b814e22
https://doi.org/10.1016/s0168-0102(02)00120-7
https://doi.org/10.1016/s0168-0102(02)00120-7