Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Kentaro Uchida"'
Autor:
Panitporn Laowpanitchakorn, Jinfeng Zeng, Marie Piantino, Kentaro Uchida, Misa Katsuyama, Michiya Matsusaki
Publikováno v:
Science and Technology of Advanced Materials, Vol 25, Iss 1 (2024)
ABSTRACTTo successfully engineer large-sized tissues, establishing vascular structures is essential for providing oxygen, nutrients, growth factors and cells to prevent necrosis at the core of the tissue. The diameter scale of the biofabricated vascu
Externí odkaz:
https://doaj.org/article/752465e4fbd34ea893611ee1d718ee34
Autor:
Yoshihide Tanaka, Masayuki Miyagi, Gen Inoue, Yusuke Hori, Kazuhide Inage, Kosuke Murata, Hisako Fujimaki, Akiyoshi Kuroda, Yuji Yokozeki, Sho Inoue, Yusuke Mimura, Shinji Takahashi, Shoichiro Ohyama, Hidetomi Terai, Masatoshi Hoshino, Akinobu Suzuki, Tadao Tsujio, Hiromitsu Toyoda, Sumihisa Orita, Yawara Eguchi, Yasuhiro Shiga, Takeo Furuya, Satoshi Maki, Shinsuke Ikeda, Eiki Shirasawa, Takayuki Imura, Toshiyuki Nakazawa, Kentaro Uchida, Seiji Ohtori, Hiroaki Nakamura, Masashi Takaso
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Sarcopenia is defined as decreasing in muscle strength and mass, and dynapenia is defined as decreasing in muscle strength and maintained muscle mass. This study elucidated the prevalence and characteristics of sarcopenia and dynapenia and e
Externí odkaz:
https://doaj.org/article/45f72a1fef454be9acc5c2206d825734
Autor:
Naoya Shibata, Yoshihisa Ohashi, Ayumi Tsukada, Dai Iwase, Jun Aikawa, Manabu Mukai, Yukie Metoki, Yui Uekusa, Masashi Sato, Gen Inoue, Masashi Takaso, Kentaro Uchida
Publikováno v:
Medicina, Vol 60, Iss 5, p 741 (2024)
(1) Introduction: Despite documented clinical and pain discrepancies between male and female osteoarthritis (OA) patients, the underlying mechanisms remain unclear. Synovial myofibroblasts, implicated in synovial fibrosis and OA-related pain, offer a
Externí odkaz:
https://doaj.org/article/89c82e69c6c14119b1f60eec004eac45
Autor:
Maho Tsuchiya, Yoshihisa Ohashi, Kensuke Fukushima, Yusei Okuda, Arisa Suto, Takashi Matsui, Yoshio Kodera, Masashi Sato, Ayumi Tsukada, Gen Inoue, Masashi Takaso, Kentaro Uchida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4085 (2024)
Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by cartilage erosion, structural changes, and inflammation. Synovial fibroblasts play a crucial role in OA pathophysiology, with abnormal fibroblastic cells contributing sig
Externí odkaz:
https://doaj.org/article/053c5555dbbe4d68a4bbd386227d903a
Autor:
Kyoko Muneshige, Kentaro Uchida, Jun Aikawa, Dai Iwase, Shotaro Takano, Masayuki Miyagi, Gen Inoue, Masashi Takaso
Publikováno v:
Central European Journal of Immunology, Vol 47, Iss 4, Pp 332-338 (2023)
Several studies have implicated b2-microglobulin (B2M) in osteoarthritis (OA) pathology. Of the main constituents of synovial tissue, synovial fibroblasts and macrophages, the latter play a pivotal role in inflammation. Although several studies have
Externí odkaz:
https://doaj.org/article/2ada3ce557074a62a2a17b6643ccdd90
Autor:
Yoshihisa Ohashi, Kensuke Fukushima, Kentaro Uchida, Tomohisa Koyama, Maho Tsuchiya, Hiroki Saito, Katsufumi Uchiyama, Naonobu Takahira, Gen Inoue, Masashi Takaso
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract We investigated the differences in outcomes after total hip arthroplasty (THA) for hip osteoarthritis (HOA) between patients with and without central sensitivity syndromes (CSSs) other than fibromyalgia (FM). After excluding two patients wit
Externí odkaz:
https://doaj.org/article/83fef77eb9c94957a104fedd844c6b87
Autor:
Tomohisa Koyama, Kensuke Fukushima, Kentaro Uchida, Yoshihisa Ohashi, Katsufumi Uchiyama, Naonobu Takahira, Masashi Takaso
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-7 (2022)
Abstract Background Hip labral tear (LT) causes various degrees of hip pain, for which there are few objective measures. Bone marrow oedema (BME), characterized by a diffuse, widely spreading change in the bone marrow, is observed in some patients wi
Externí odkaz:
https://doaj.org/article/8853bd2cf8ff4feaaa1cfa48318a03f2
Autor:
Ayumi Tsukada, Ken Takata, Jun Aikawa, Dai Iwase, Manabu Mukai, Yui Uekusa, Yukie Metoki, Gen Inoue, Masayuki Miyagi, Masashi Takaso, Kentaro Uchida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 877 (2024)
Diabetes mellitus (DM) has been suggested as a potential risk factor for knee osteoarthritis (KOA), and its underlying mechanisms remain unclear. The infrapatellar fat pad (IPFP) contributes to OA through inflammatory mediator secretion. Mast cells
Externí odkaz:
https://doaj.org/article/9ac11c848c7f44c9abcc9f9513906c91
Autor:
Maho Tsuchiya, Yoshihisa Ohashi, Yoshio Kodera, Masashi Satoh, Takashi Matsui, Kensuke Fukushima, Dai Iwase, Jun Aikawa, Manabu Mukai, Gen Inoue, Masashi Takaso, Kentaro Uchida
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3047 (2023)
Recent studies utilizing single-cell analysis have unveiled the presence of various fibroblast (Fb) subsets within the synovium under inflammatory conditions in osteoarthritis (OA), distinguishing them from those in rheumatoid arthritis (RA). Moreove
Externí odkaz:
https://doaj.org/article/14985672141845a4bcea60fb6cc3694a
Autor:
Tomohisa Koyama, Kentaro Uchida, Makoto Itakura, Masayuki Miyagi, Ryo Tazawa, Gen Inoue, Kensuke Fukushima, Yoshihisa Ohashi, Ayumi Tsukada, Masashi Takaso
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 7, Pp 3146-3155 (2022)
Expression of the apelin receptor, APJ, in skeletal muscle (SM) is known to decrease with age, but the underlying mechanism remains unclear. Increased tumor necrosis factor (TNF)-α levels are observed in SM with age and are associated with muscle at
Externí odkaz:
https://doaj.org/article/5e8d4c3f56cb408b8970096882664932