Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kentaro Takeuchi"'
Autor:
Akira Hara, Haruhiko Akiyama, Andrew B. Lassar, Kentaro Takeuchi, Kazu Matsumoto, Hiroyasu Ogawa, Norishige Kuramitsu, Atsushi Goto, Keisuke Akaike, Yoshiyuki Suehara, Hitomi Aoki
Publikováno v:
Osteoarthritis Cartilage
Summary Objective Low molecular weight compounds that reduce the expression of MMP13 at the mRNA level might serve as disease-modifying osteoarthritis (OA) drugs (DMOADs). The objective of this study was to identify a candidate DMOAD that targets MMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db089a3c3a334c4013012583d978511d
https://doi.org/10.1016/j.joca.2021.08.001
https://doi.org/10.1016/j.joca.2021.08.001
Publikováno v:
Journal of the Japanese Association for Petroleum Technology. 86:105-111
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56da50d9241bc8796623b2a65f9c768a
https://doi.org/10.3720/japt.86.105
https://doi.org/10.3720/japt.86.105
Publikováno v:
Journal of the Japan Health Physics Society; 2023, Vol. 58 Issue 2, p76-90, 15p
Autor:
Yoon-Koo Kang, Li-Tzong Chen, Min-Hee Ryu, Do-Youn Oh, Sang Cheul Oh, Hyun Cheol Chung, Keun-Wook Lee, Takeshi Omori, Kohei Shitara, Shinichi Sakuramoto, Ik-Joo Chung, Kensei Yamaguchi, Ken Kato, Sun Jin Sym, Shigenori Kadowaki, Kunihiro Tsuji, Jen-Shi Chen, Li-Yuan Bai, Sung-Yong Oh, Yasuhiro Choda, Hisateru Yasui, Kentaro Takeuchi, Yoshinori Hirashima, Shunsuke Hagihara, Narikazu Boku
Publikováno v:
The Lancet. Oncology. 23(2)
The additive or synergistic sustained antitumour effect of immune checkpoint inhibitors in combination with oxaliplatin-based chemotherapy has previously been reported. We investigated the efficacy of nivolumab plus oxaliplatin-based chemotherapy ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d04c9b328ca2f82d26c84f35274c75
https://pubmed.ncbi.nlm.nih.gov/36267012
https://pubmed.ncbi.nlm.nih.gov/36267012
Publikováno v:
The Chemical Record. 20:403-412
A transition metal catalyzed alkylation with an alkyl halide is one of the most difficult reactions to achieve, because of the difficult oxidative addition of an alkyl-halogen bond to a metal, and the tendency of the resulting alkylmetal intermediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2476e8afa8172c54d1c0aaf7e0523d0
https://doi.org/10.1002/tcr.201900053
https://doi.org/10.1002/tcr.201900053
Publikováno v:
Angewandte Chemie International Edition. 56:11610-11614
There are several reports on the synthesis of alkylamines, but most of the reported methods are not suitable for the synthesis of hindered amines. In this research, we found that a copper catalyst is effective for the formation of congested C-N bonds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19edf150ed12362718a814f467c781bb
https://doi.org/10.1002/anie.201706293
https://doi.org/10.1002/anie.201706293
Publikováno v:
IEEJ Transactions on Fundamentals and Materials. 137:58-64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c030034f963ab33843f403d9e093fde6
https://doi.org/10.1541/ieejfms.137.58
https://doi.org/10.1541/ieejfms.137.58
Publikováno v:
Archives of Orthopaedic and Trauma Surgery. 136:1337-1342
Medial opening wedge high tibial osteotomy (HTO) is a realignment of the lower limb. Despite accurate preoperative planning and careful surgical techniques, many HTOs result in alignment correction errors. These alignment correction errors may be due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6466ea450e963cf066d959835aaecd
https://doi.org/10.1007/s00402-016-2521-x
https://doi.org/10.1007/s00402-016-2521-x
Publikováno v:
Chemistry Letters. 46:644-646
We found that dichloromethane is a powerful chlorinating reagent for the congested 3° and 2° Csp3–Br bond of α-bromocarbonyl amides, esters, and ketones. In the presence of an appropriate copper complex as a catalyst, the desired chlorination oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67b5909dc926f35e748c7879c709a33
https://doi.org/10.1246/cl.170062
https://doi.org/10.1246/cl.170062
Autor:
Nobuo Terabayashi, Haruhiko Akiyama, Hiroyasu Ogawa, Kenji Kawashima, Kentaro Takeuchi, Kazu Matsumoto
Publikováno v:
Modern rheumatology. 27(3)
Although lubricin plays a role in controlling inflammation and pain as well as being a mechanical lubricant, clinical relevance of lubricin concentration in synovial fluid (SF) is unknown. The purpose was to determine whether lubricin concentration i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d2a8dae2ffdba1d1505e2ed5814406
https://pubmed.ncbi.nlm.nih.gov/27435056
https://pubmed.ncbi.nlm.nih.gov/27435056