Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Kentaro Otani"'
Autor:
Takeshi Tokudome, Kentaro Otani
Publikováno v:
Biology, Vol 11, Iss 9, p 1351 (2022)
Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals. ANP and BNP are hormones secreted from the
Externí odkaz:
https://doaj.org/article/3db4dcf888b742cfbe6104c218c95987
Autor:
Hidetoshi Tsuda, Kenichi Yamahara, Kentaro Otani, Masayoshi Okumi, Koji Yazawa, Jun-Ya Kaimori, Akihiko Taguchi, Kenji Kangawa, Tomoaki Ikeda, Shiro Takahara, Yoshitaka Isaka M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Mesenchymal stem cells (MSCs) are an attractive therapeutic cell source for treating renal diseases. MSC administration has been shown to improve renal function, although the underlying mechanisms are not completely understood. We recently showed tha
Externí odkaz:
https://doaj.org/article/ca13213768e04039beafe2265526e0cc
Autor:
Kenichi Yamahara, Kazuhiko Harada, Makiko Ohshima, Shin Ishikane, Shunsuke Ohnishi, Hidetoshi Tsuda, Kentaro Otani, Akihiko Taguchi, Toshihiro Soma, Hiroyasu Ogawa, Shinji Katsuragi, Jun Yoshimatsu, Mariko Harada-Shiba, Kenji Kangawa, Tomoaki Ikeda
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88319 (2014)
Although mesenchymal stem cells (MSCs) can be obtained from the fetal membrane (FM), little information is available regarding biological differences in MSCs derived from different layers of the FM or their therapeutic potential. Isolated MSCs from b
Externí odkaz:
https://doaj.org/article/cd3eb48bb5864dc2b39cc691ae0042c2
Autor:
Sergej Popov, Hiroshi Takemori, Takeshi Tokudome, Yuanjie Mao, Kentaro Otani, Naoki Mochizuki, Nuno Pires, Maria João Pinho, Anders Franco-Cereceda, Lucia Torielli, Mara Ferrandi, Anders Hamsten, Patricio Soares-da-Silva, Per Eriksson, Alejandro M Bertorello, Laura Brion
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95771 (2014)
Cardiac left ventricle hypertrophy (LVH) constitutes a major risk factor for heart failure. Although LVH is most commonly caused by chronic elevation in arterial blood pressure, reduction of blood pressure to normal levels does not always result in r
Externí odkaz:
https://doaj.org/article/75e34486a9c44ffc8a7b873075db65fc
Autor:
Miki Yokokawa, Shunsuke Ohnishi M.D., Ph.D., Hatsue Ishibashi-Ueda, Hiroaki Obata, Kentaro Otani, Yoshinori Miyahara, Koichi Tanaka, Wataru Shimizu, Kazuo Nakazawa, Kenji Kangawa, Shiro Kamakura, Soichiro Kitamura, Noritoshi Nagaya
Publikováno v:
Cell Transplantation, Vol 17 (2008)
Mesenchymal stem cells (MSCs) are multipotent cells that differentiate into a variety of lineages including myocytes and vascular endothelial cells. However, little information is available regarding the therapeutic potential of MSCs in patients with
Externí odkaz:
https://doaj.org/article/e87bfbd956fc47feb70ae96a5fef0161
Autor:
Takeshi Tokudome, Kentaro Otani, Yuanjie Mao, Lars Jørn Jensen, Yuji Arai, Takahiro Miyazaki, Takashi Sonobe, James T. Pearson, Tsukasa Osaki, Naoto Minamino, Junji Ishida, Akiyoshi Fukamizu, Hayato Kawakami, Daisuke Onozuka, Kunihiro Nishimura, Mikiya Miyazato, Hirohito Nishimura
Publikováno v:
Hypertension. 79:1409-1422
Background: ANP (atrial natriuretic peptide), acting through NPR1 (natriuretic peptide receptor 1), provokes hypotension. Such hypotension is thought to be due to ANP inducing vasodilation via NPR1 in the vasculature; however, the underlying mechanis
Autor:
Mari Kaneko, Naoto Minamino, Shunsuke Murata, Jun Yoshimatsu, Go Shioi, Tsukasa Osaki, Jun Hino, Kentaro Otani, Takeshi Tokudome, Hirohito Nishimura, Kunihiro Nishimura, Junji Ishida, Takuya Ensho, Kenji Kangawa, Tomoaki Ikeda, Kazuwa Nakao, Chiaki Nagai-Okatani, Yuji Arai, Takeshi Hasegawa, Mikiya Miyazato, Mariko Harada-Shiba, Yuanjie Mao, Ichiro Kishimoto, Chizuko Kamiya, Misa Takegami, Akiyoshi Fukamizu
Publikováno v:
Circulation. 141:571-588
Background: The maternal circulatory system and hormone balance both change dynamically during pregnancy, delivery, and the postpartum period. Although atrial natriuretic peptides and brain natriuretic peptides produced in the heart control circulato
Publikováno v:
Peptides. 111:42-46
Ghrelin, a growth hormone-releasing peptide that was first discovered in the stomach of rats in 1999, is an endogenous ligand of growth hormone secretagogue receptor. Ghrelin exerts its potent growth hormone-releasing and orexigenic activities by bin
Publikováno v:
Life Sciences. 209:466-471
Aims Smooth muscle cells (SMCs) play a role in medial vascular calcification, which can be stimulated by high levels of serum phosphate and inflammatory mediators. The aim of this study was to investigate whether mitogen-activated protein kinases (MA
Publikováno v:
Ultrasound in Medicine & Biology. 44:1063-1073
The usefulness of ultrasound molecular imaging with αvβ3 integrin-targeted microbubbles for detecting tumor angiogenesis has been demonstrated. Recently, we developed αvβ3 integrin-targeted microbubbles by modifying clinically available microbubb