Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kentaro Ohkuni"'
Autor:
Kentaro Ohkuni, Nagesh Pasupala, Jennifer Peek, Grace Lauren Holloway, Gloria D. Sclar, Reuben Levy-Myers, Richard E. Baker, Munira A. Basrai, Oliver Kerscher
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Cell viability and gene expression profiles are altered in cellular models of neurodegenerative disorders such as Huntington’s Disease (HD). Using the yeast model system, we show that the SUMO-targeted ubiquitin ligase (STUbL) Slx5 reduces the toxi
Externí odkaz:
https://doaj.org/article/3bc68a8c17d340b5ad33f25c6dff5792
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1617 (2008)
The spindle checkpoint ensures the accurate segregation of chromosomes by monitoring the status of kinetochore attachment to microtubules. Simultaneous mutations in one of several kinetochore and cohesion genes and a spindle checkpoint gene cause a s
Externí odkaz:
https://doaj.org/article/af16efefdd8c4213b206b8712f9974b2
Publikováno v:
Nucleic Acids Res
Restricting the localization of CENP-A (Cse4 in Saccharomyces cerevisiae) to centromeres prevents chromosomal instability (CIN). Mislocalization of overexpressed CENP-A to non-centromeric chromatin contributes to CIN in budding and fission yeasts, fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddbdec688057f8b77300d15c758e3c6
https://doi.org/10.1093/nar/gkac135
https://doi.org/10.1093/nar/gkac135
Autor:
Kentaro Ohkuni1, Levy-Myers, Reuben1,2, Warren, Jack1, Wei-Chun Au1, Yoshimitsu Takahashi1, Baker, Richard E.3, Basrai, Munira A.1 basraim@nih.gov
Publikováno v:
G3: Genes | Genomes | Genetics. Apr2018, Vol. 8 Issue 4, p1215-1223. 9p.
Autor:
Evelyn Suva, Jessica R. Eisenstatt, Wei-Chun Au, Michael Costanzo, Kentaro Ohkuni, Munira A. Basrai, Olivia Preston, Charles Boone, Loran Gliford
Publikováno v:
Genetics
Mislocalization of the centromeric histone H3 variant (Cse4 in budding yeast, CID in flies, CENP-A in humans) to noncentromeric regions contributes to chromosomal instability (CIN) in yeast, fly, and human cells. Overexpression and mislocalization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbbc3c3e6fbddcdb5eeaf51a8bcb81b
https://doi.org/10.1093/genetics/iyab033
https://doi.org/10.1093/genetics/iyab033
Autor:
Eisenstatt, Kentaro Ohkuni, Munira A. Basrai, Michael Costanzo, Evelyn Suva, Charles Boone, Wei-Chun Au, Olivia Preston
Mislocalization of the centromeric histone H3 variant (Cse4 in budding yeast, CID in flies, CENP-A in humans) to non-centromeric regions contributes to chromosomal instability (CIN) in yeast, fly, and human cells. Overexpression and mislocalization o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebea20fe6ff5b93ce468ee92382a60c0
https://doi.org/10.1101/2020.05.29.124032
https://doi.org/10.1101/2020.05.29.124032
Autor:
Evelyn Suva, Paul S. Meltzer, Robert L. Walker, Reuben Levy-Myers, Richard Baker, Kentaro Ohkuni, Wei-Chun Au, Munira A. Basrai
Publikováno v:
Genetics
Centromeric localization of CENP-A (Cse4 in Saccharomyces cerevisiae, CID in flies, CENP-A in humans) is essential for faithful chromosome segregation. Mislocalization of overexpressed CENP-A contributes to aneuploidy in yeast, flies, and humans, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b6ab9a54bd619843f9b0892f277300
https://europepmc.org/articles/PMC7153950/
https://europepmc.org/articles/PMC7153950/
Autor:
Richard Baker, Yoshimitsu Takahashi, Kentaro Ohkuni, Jack Warren, Reuben Levy-Myers, Wei-Chun Au, Munira A. Basrai
Publikováno v:
G3: Genes|Genomes|Genetics
Stringent regulation of cellular levels of evolutionarily conserved centromeric histone H3 variant (CENP-A in humans, CID in flies, Cse4 in yeast) prevents its mislocalization to non-centromeric chromatin. Overexpression and mislocalization of CENP-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4560b4c0839782648217118a2c76c41f
https://doi.org/10.1534/g3.117.300419
https://doi.org/10.1534/g3.117.300419
Autor:
Kentaro Ohkuni, Alyona Fulp, Nagesh Pasupala, Alexander V. Strunnikov, Richard Baker, Wei Chun Au, Munira A. Basrai, Yoshimitsu Takahashi, Reuben Levy-Myers, Jack Warren, Oliver Kerscher, Josh Lawrimore, Kerry Bloom
Publikováno v:
Molecular Biology of the Cell
A new posttranslational modification is found of centromeric histone H3 variant Cse4. Cse4 is sumoylated by E3 ligases Siz1 and Siz2 and ubiquitinated by Slx5, a Sumo-targeted ubiquitin ligase. Slx5 regulates ubiquitin-mediated proteolysis of Cse4 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaca5999e565a6a4f18d2a932631e517
http://europepmc.org/articles/PMC4850037
http://europepmc.org/articles/PMC4850037
Autor:
Eisenstatt, Jessica R.1, Kentaro Ohkuni1, Wei-Chun Au1, Preston, Olivia1, Gliford, Loran1, Suva, Evelyn1, Costanzo, Michael2,3, Boone, Charles2,3, Basrai, Munira A.1 basraim@mail.nih.gov
Publikováno v:
Genetics. May2021, Vol. 218 Issue 1, p1-19. 19p.