Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Kentaro Nakashima"'
Autor:
Kentaro Nakashima, Yuya Kunisaki, Kentaro Hosokawa, Kazuhito Gotoh, Hisayuki Yao, Ryosuke Yuta, Yuichiro Semba, Jumpei Nogami, Yoshikane Kikushige, Patrick S. Stumpf, Ben D. MacArthur, Dongchon Kang, Koichi Akashi, Shouichi Ohga, Fumio Arai
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Protection of telomeres 1a (POT1a) is a telomere binding protein. A decrease of POT1a is related to myeloid-skewed haematopoiesis with ageing, suggesting that protection of telomeres is essential to sustain multi-potency. Since mesenchymal s
Externí odkaz:
https://doaj.org/article/e55a84a5ea34472ba25f72989b580bf5
Autor:
Yuki Kata, Yu Hara, Yoichi Tagami, Aya Yabe, Kota Murohashi, Ryo Nagasawa, Kentaro Nakashima, Hiroaki Fujii, Yusuke Saigusa, Masafumi Shiida, Keisuke Watanabe, Nobuyuki Horita, Nobuaki Kobayashi, Takeshi Kaneko
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The present study aimed to evaluate whether serum heme oxygenase (HO)-1 could be a reliable blood biomarker for diagnosing acute exacerbations (AEs) of both idiopathic interstitial pneumonia (IIP) and secondary interstitial pneumonia (SIP).
Externí odkaz:
https://doaj.org/article/a108562c22834a729e9c177fe38f6c5d
Autor:
Seigo Katakura, Nobuaki Kobayashi, Hisashi Hashimoto, Chisato Kamimaki, Katsushi Tanaka, Sousuke Kubo, Kentaro Nakashima, Shuhei Teranishi, Saki Manabe, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 10, Pp 2975-2982 (2020)
Background Advanced non‐small cell lung cancer (NSCLC) has a high mortality rate and poor prognosis. However, outcomes have gradually improved after the introduction of novel immunotherapies, including immune checkpoint inhibitors (ICIs). Although
Externí odkaz:
https://doaj.org/article/16617066622c41d597b7c6fc08914603
Autor:
Nobuaki Kobayashi, Hisashi Hashimoto, Chisato Kamimaki, Ryo Nagasawa, Katsushi Tanaka, Sousuke Kubo, Seigo Katakura, Hao Chen, Nobuyuki Hirama, Ryota Ushio, Ayako Aoki, Kentaro Nakashima, Shuhei Teranishi, Saki Manabe, Hiroki Watanabe, Nobuyuki Horita, Keisuke Watanabe, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 8, Pp 2125-2129 (2020)
Introduction As most patients with epidermal growth factor receptor (EGFR)‐mutant non‐small cell lung cancer (NSCLC) develop progressive disease after treatment with osimertinib, it is important to develop more effective treatment options. Afatin
Externí odkaz:
https://doaj.org/article/087b6fea136f41399c90d1366b3a7289
Publikováno v:
Thoracic Cancer, Vol 11, Iss 5, Pp 1258-1264 (2020)
Abstract Background Bevacizumab, a monoclonal antibody against vascular endothelial growth factor (VEGF)‐A, has shown efficacy in patients with advanced nonsquamous non‐small cell lung cancer (NSCLC). There are no identified or clinically validat
Externí odkaz:
https://doaj.org/article/aaafe5cc0cf34cefa2ac76fbce692372
Autor:
Tamaki Ueda, Yuhki Koga, Hiroshi Yoshikawa, Mika Tanabe, Kanako Yamana, Utako Oba, Kentaro Nakashima, Hiroaki Ono, Takuya Ichimura, Shunji Hasegawa, Wakako Kato, Tetsuko Kobayashi, Hideki Nakayama, Yasunari Sakai, Tadamasa Yoshitake, Saiji Ohga, Yoshinao Oda, Shigenobu Suzuki, Koh-Hei Sonoda, Shouichi Ohga
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Retinoblastoma is an ocular tumor in infants with cancer predisposition. Treatment of the rare tumor needs to be optimized for ocular preserved survival without second primary malignancy (SPM). Methods We studied the outcomes of a
Externí odkaz:
https://doaj.org/article/32580084343d4b7b83c2f725ab75776f
Autor:
Yoichi Tagami, Yu Hara, Kota Murohashi, Ryo Nagasawa, Yurika Nishikawa, Meiro Tanaka, Ayako Aoki, Katsushi Tanaka, Kentaro Nakashima, Keisuke Watanabe, Nobuyuki Horita, Nobuaki Kobayashi, Masaki Yamamoto, Makoto Kudo, Koji Okudela, Takeshi Kaneko
Publikováno v:
Canadian Respiratory Journal, Vol 2021 (2021)
Background. Serum Krebs von den Lungen-6 (KL-6) measurement is widely used to assess disease activity or prognosis in patients with interstitial lung diseases (ILDs). However, the clinical differences between high and low serum KL-6 levels at the tim
Externí odkaz:
https://doaj.org/article/440469d42b0e4968988c719c4ad31a85
Autor:
Kentaro Nakashima, Takashi Sato, Suguru Shigemori, Takeshi Shimosato, Masaharu Shinkai, Takeshi Kaneko
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Silicosis, a progressive inflammatory lung disease attributed mainly to occupational exposure to silica dust, shows loss of lung function even after cessation of exposure. In addition to conventional evaluation methods such as che
Externí odkaz:
https://doaj.org/article/a74880aec6fc4e03994ae6734695a5bf
Autor:
Noriko Ohyama, Michiko Torio, Kentaro Nakashima, Yuuki Koga, Shunsuke Kanno, Hisanori Nishio, Kei Nishiyama, Momoko Sasazuki, Haru Kato, Hiroshi Asakura, Satoshi Akamine, Masafumi Sanefuji, Yoshito Ishizaki, Yasunari Sakai, Shouichi Ohga
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 16, Iss 1, Pp 1-4 (2017)
Abstract Background Botulism is a potentially fatal infection characterized by progressive muscle weakness, bulbar paralysis, constipation and other autonomic dysfunctions. A recent report suggested that cancer chemotherapy might increase the risk fo
Externí odkaz:
https://doaj.org/article/f6b4967969d54636b5837c840e73e7e5
Autor:
Ayako Aoki, Yu Hara, Koji Okudela, Yoshihiro Ishikawa, Kosei Doshita, Hisashi Hashimoto, Kentaro Nakashima, Nobuyuki Horita, Nobuaki Kobayashi, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 11, Pp 3407-3408 (2020)
Abstract A 77‐year‐old man who had a persistent productive cough for one month was admitted to our hospital. Chest computed tomography (CT) revealed subpleural nodular opacities, irregular pleural thickening with bilateral basal predominance, and
Externí odkaz:
https://doaj.org/article/2044d1cdade848ab9adbbf42bbe2adf8