Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kentaro Kumazawa"'
Autor:
Hiroaki Tagaya, Kosuke Ishikawa, Yoshito Hosokawa, Shun Kobayashi, Yukino Ueoka, Mayuna Shimada, Yasuko Ohashi, Hirofumi Mikami, Mizuki Yamamoto, Tatsuya Ihara, Kentaro Kumazawa, Kosuke Sugihara, Naoki Goshima, Shinya Watanabe, Kentaro Semba
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background To obtain a deep understanding of the mechanism by which breast cancer develops, the genes involved in tumorigenesis should be analyzed in vivo. Mouse mammary gland can regenerate completely from a mammary stem cell (MaSC), which
Externí odkaz:
https://doaj.org/article/0fd362f3c8ae4b0899c342538d77e696
Autor:
Naoki Goshima, Y Hosokawa, Shinya Watanabe, Mizuki Yamamoto, T Muramkami, James G. Fujimoto, Kentaro Semba, Kentaro Kumazawa, E Ito, Tomohiko Ihara, K Ishikawa
Publikováno v:
Oncogene. 36:2023-2029
Screening for oncogenes has mostly been performed by in vitro transformation assays. However, some oncogenes might not exhibit their transforming activities in vitro unless putative essential factors from in vivo microenvironments are adequately supp
Autor:
Masahiro Ota, Kosaku Fujiwara, Tomoe Taira, Jimbo Takeshi, Takashi Suzuki, Takahiro Komatsu, Takeshi Isoyama, Mana Hatanaka, Noriyasu Haginoya, Naoyuki Maeda, Kentaro Kumazawa
Publikováno v:
Oncotarget
The AXL receptor tyrosine kinase is involved in signal transduction in malignant cells. Recent studies have shown that the AXL upregulation underlies epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) resistance in EGFR-mutant no
Autor:
Mizuki Yamamoto, Tatsuya Ihara, Kosuke Ishikawa, Yukino Ueoka, Kosuke Sugihara, Naoki Goshima, Shun Kobayashi, Hirofumi Mikami, Kentaro Semba, Mayuna Shimada, Hiroaki Tagaya, Kentaro Kumazawa, Shinya Watanabe, Yasuko Ohashi, Yoshito Hosokawa
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background To obtain a deep understanding of the mechanism by which breast cancer develops, the genes involved in tumorigenesis should be analyzed in vivo. Mouse mammary gland can regenerate completely from a mammary stem cell (MaSC), which enables u
Autor:
Hirokazu Ohbayashi, Naoki Goshima, Hiromi Mochizuki, Jiro Fujimoto, Kosuke Ishikawa, Shinya Watanabe, Atsuka Matsui, Ayano Doi, Makoto Saito, Yoshifumi Kawamura, Sakura Azuma, Yuka Yanagisawa, Reiko Honma, Kentaro Kumazawa, Emi Ito, Kentaro Semba, Shiori Takebe, Takaomi Ishida, Yukiko Kato, Jun-ichi Imai
Publikováno v:
FEBS letters. 586(12)
Gene amplification is a major genetic alteration in human cancers. Amplicons, amplified genomic regions, are believed to contain “driver” genes responsible for tumorigenesis. However, the significance of co-amplified genes has not been extensivel
Autor:
Shiori Takebe, Tadashi Yamamoto, Atsuka Matsui, Kentaro Semba, Kentaro Kumazawa, Takuya Amari, Masaaki Oyama, Ayano Doi, Makoto Saito
Publikováno v:
Breast Cancer-Carcinogenesis, Cell Growth and Signalling Pathways
ErbB2, one of the receptor tyrosine kinase superfamily has attracted the attention of cancer researchers since its discovery. Thirty years ago, ErbB2 was discovered as an oncogene that transforms NIH3T3 cells. The first decade of ErbB2 research revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb1a5570de362e17e153ed18e561870
http://www.intechopen.com/articles/show/title/erbb2-her2-its-contribution-to-basic-cancer-biology-and-the-development-of-molecular-targeted-therap
http://www.intechopen.com/articles/show/title/erbb2-her2-its-contribution-to-basic-cancer-biology-and-the-development-of-molecular-targeted-therap