Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Kentaro Hozumi"'
Publikováno v:
Polymers, Vol 7, Iss 2, Pp 281-297 (2015)
The basement membrane, a thin extracellular matrix, plays a critical role in tissue development and repair. Laminins are the major component of basement membrane and have diverse biological activities. We have identified various cell-adhesive peptide
Externí odkaz:
https://doaj.org/article/d66be1ba72cd432fb6a37b994ad1cb65
Autor:
Yurie Enomoto-Okawa, Yuka Maeda, Nozomi Harashima, Yumika Sugawara, Fumihiko Katagiri, Kentaro Hozumi, Kam Man Hui, Motoyoshi Nomizu, Yuji Ito, Yamato Kikkawa
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0167860 (2017)
The Lutheran glycoprotein (Lu), also known as basal cell adhesion molecule (B-CAM), is an Ig superfamily (IgSF) transmembrane receptor for laminin α5. Although Lu is not present in normal hepatocytes, its expression is significantly increased in hep
Externí odkaz:
https://doaj.org/article/67b69e0d16ed4dd59720d33e4d00ae3e
Autor:
Hironao Yamada, Sakiko Mori, Takeshi Miyakawa, Ryota Morikawa, Fumihiko Katagiri, Kentaro Hozumi, Yamato Kikkawa, Motoyoshi Nomizu, Masako Takasu
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149474 (2016)
Peptides with cell attachment activity are beneficial component of biomaterials for tissue engineering. Conformational structure is one of the important factors for the biological activities. The EF1 peptide (DYATLQLQEGRLHFMFDLG) derived from laminin
Externí odkaz:
https://doaj.org/article/5675ca44add848348c14811b97f034dd
Autor:
Kentaro Hozumi, Motoyoshi Nomizu
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2713 (2018)
Biomaterials are important for cell and tissue engineering. Chitosan is widely used as a scaffold because it is easily modified using its amino groups, can easily form a matrix, is stable under physiological conditions, and is inactive for cell adhes
Externí odkaz:
https://doaj.org/article/b41449d3dac647aca1cb75644cc7d47b
Autor:
Wataru Nomura, Yudai Matsuzaki, Motoyoshi Nomizu, Kentaro Hozumi, Hirokazu Tamamura, Takuya Kobayakawa
Publikováno v:
ACS Medicinal Chemistry Letters. 9:6-10
The first rapid and efficient chemical synthesis of a cyclic Arg-Gly-Asp (RGD) peptide containing a chloroalkene dipeptide isostere (CADI) is reported. By a developed synthetic method, an N-tert-butylsulfonyl protected CADI was obtained utilizing dia
Autor:
Jun Kumai, Fumihiko Katagiri, Yumika Sugawara, Motoyoshi Nomizu, Yamato Kikkawa, Shogo Fujii, Kazuki Ikari, Kentaro Hozumi, Nozomi Harashima
Publikováno v:
Journal of Peptide Science. 23:666-673
Laminin-511, a major component of endothelial basement membrane, consists of α5, β1, and γ1 chains. The short arm region of the α5 chain is a structural feature of endothelial laminins. In this study, we identified active sequences for human umbi
Autor:
Kentaro Hozumi, Yamato Kikkawa, Motoyoshi Nomizu, Jun Kumai, Fumihiko Katagiri, Keisuke Hamada, Yuji Yamada
Publikováno v:
Journal of peptide science : an official publication of the European Peptide SocietyREFERENCES. 25(12)
Human laminin-511 (α5β1γ1) and its truncated protein, laminin-511 E8 fragment, bind to integrin α6β1 and have been widely used for embryonic stem cell and induced pluripotent stem cell culture under feeder-free conditions. In this study, we focu
Autor:
Fumihiko Katagiri, Yui Teranishi, Sayaka Enomoto, Yamato Kikkawa, Motoyoshi Nomizu, Kentaro Hozumi
Publikováno v:
Journal of biomaterials applications. 33(7)
Extracellular matrix molecules are recognized by several integrin subtypes, making identification of cross-talk among different integrin subtypes difficult. Here, we evaluated the cross-talk of integrin subtypes using four different integrin-binding
Publikováno v:
Biopolymers. 106:512-520
Peptide-polysaccharide matrices can mimic extracellular matrix structure and function and are useful for tissue and cell engineering. The spacer between the peptide and the polysaccharide is important for both peptide conformation and the interaction
Autor:
Mari Miyagi, Fumihiko Katagiri, Kentaro Hozumi, Rika Nagao, Motoyoshi Nomizu, Keiko Takasaki, Kyotaro Nakamura, Haruna Hori, Yamato Kikkawa
Publikováno v:
BioResearch Open Access, Vol 5, Iss 1, Pp 356-366 (2016)
BioResearch Open Access
BioResearch Open Access
Mimicking the biological function of the extracellular matrix is an approach to developing cell adhesive biomaterials. The RGD peptide, derived from fibronectin (Fn), mainly binds to integrin αvβ3 and has been widely used as a cell adhesive peptide