Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Kentaro Hirao"'
Autor:
Jun Ogata, Kentaro Hirao, Kenya Nishioka, Arisa Hayashida, Yuanzhe Li, Hiroyo Yoshino, Soichiro Shimizu, Nobutaka Hattori, Yuzuru Imai
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3708 (2021)
Leucine-rich repeat kinase 2 (LRRK2) is a major causative gene of late-onset familial Parkinson’s disease (PD). The suppression of kinase activity is believed to confer neuroprotection, as most pathogenic variants of LRRK2 associated with PD exhibi
Externí odkaz:
https://doaj.org/article/7dcda85337764516b86ff84f5e98cfe9
Autor:
Kentaro Hirao, Haruo Hanyu, Tomohiko Sato, Hidekazu Kanetaka, Soichiro Shimizu, Hirofumi Sakurai, Toshihiko Iwamoto
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 1, Iss 1, Pp 62-74 (2011)
Aims: To determine the effect of diabetes mellitus (DM) on regional cerebral blood flow (rCBF) patterns in patients with Alzheimer’s disease (AD). Methods: We investigated the initial rCBF of 71 AD patients (36 without DM and 35 with DM) and the fi
Externí odkaz:
https://doaj.org/article/50a7f9b809b14a8bac66a15f498ba861
Autor:
Haruo, Hanyu, Yumi, Koyama, Haruka, Horita, Toshinori, Aoki, Tomohiko, Sato, Naoto, Takenoshita, Hidekazu, Kanetaka, Soichiro, Shimizu, Kentaro, Hirao, Sadayoshi, Watanabe
Publikováno v:
Journal of Alzheimer's Disease. 87:781-789
Background: Alzheimer’s disease (AD) is a biologically heterogenous disease. Previous studies have reported the existence of various AD subtypes, and the various clinical features of the subtypes. However, inconsistent results have been obtained. O
Autor:
Yusuke MINAMIO, Hisaya TANAKA, Raita FUKASAWA, Kentaro HIRAO, Akito TSUGAWA, Soichiro SHIMIZU
Publikováno v:
International Symposium on Affective Science and Engineering. :1-4
Publikováno v:
International Symposium on Affective Science and Engineering. :1-4
Autor:
Yuri NISHIZAWA, Hisaya TANAKA, Raita FUKASAWA, Kentaro HIRAO, Akito TSUGAWA, Soichiro SHIMIZU
Publikováno v:
International Symposium on Affective Science and Engineering. :1-4
Autor:
Shuntaro Serisawa, Daisuke Hirose, Aya Imanishi, Yusuke Ogawa, Haruo Hanyu, Shu Sakurai, Hidekazu Kanetaka, Akito Tsugawa, Yoshitsugu Kaneko, Takashi Kanbayashi, Hirofumi Sakurai, Naoto Takenoshita, Kentaro Hirao, Soichiro Shimizu, Yuta Inagawa
Publikováno v:
Journal of Alzheimer's Disease. 73:117-123
Background Recently, many studies have investigated the association between orexin A and Alzheimer's disease (AD). However, it remains to be determined whether the observed changes in orexin A levels are associated with pathological changes underlyin
Autor:
Haruo Hanyu, Yumi Koyama, Haruka Horita, Toshinori Aoki, Tomohiko Sato, Hidekazu Kanetaka, Soichiro Shimizu, Kentaro Hirao
Publikováno v:
Current Alzheimer research. 19(2)
Background/Objective:: Although a large number of studies have been performed on the association between Alzheimer’s disease (AD) and type 2 diabetes mellitus (DM), the underlying pathophysiology of AD associated with DM has not been fully elucidat
Autor:
Tomohiko Sato, Hidekazu Kanetaka, Kentaro Hirao, Haruo Hanyu, Soichiro Shimizu, Toshinori Aoki, Yumi Koyama, Haruka Horita
Publikováno v:
Journal of Alzheimer's disease : JAD. 84(1)
Background: In Alzheimer’s disease (AD) patients, the severity of cognitive impairment is thought to correlate with the degree of brain imaging abnormalities. However, some patients show only mild cognitive deficit, despite severe brain atrophy on
Autor:
Shuntaro Serisawa, Yuta Inagawa, Yusuke Ogawa, Naoto Takenoshita, Soichiro Shimizu, Shu Sakurai, Yoshitsugu Kaneko, Hirofumi Sakurai, Hidekazu Kanetaka, Kentaro Hirao, Akito Tsugawa, Daisuke Hirose
Publikováno v:
Journal of Alzheimer's Disease. 77:539-541
The ongoing coronavirus disease 2019 (COVID-19) pandemic has substantially affected patients with dementia and their caregivers. However, we found not all Alzheimer’s disease (AD) patients were afraid of COVID-19 infection. Therefore, we investigat