Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kentaro Enjo"'
Autor:
Satoshi Fukasawa, Hiroyoshi Suzuki, Kazushiro Kawaguchi, Hidehisa Noguchi, Kentaro Enjo, Namphuong Tran, Mary Todd, Karim Fizazi, Nobuaki Matsubara
Publikováno v:
Japanese Journal of Clinical Oncology
Abiraterone acetate plus prednisone in addition to androgen-deprivation therapy (ADT) was efficacious versus ADT alone in Japanese men with metastatic hormone-naïve prostate cancer. No new safety concerns were identified.
Objectives To evaluate
Objectives To evaluate
Publikováno v:
Current medical research and opinion. 34(10)
Objective: The objective was to assess the burden of chemotherapy for castration-resistant prostate cancer (CRPC) in Japan. Methods: Utilizing a large administrative hospital database we compared a set of outcome measures 12 months before and after i
Autor:
Akio Kakefuda, Mitsuaki Ohta, Yukio Otsuka, Aya Kikuchi, Takashi Furutani, Kentaro Enjo, Kazushi Watanabe, Yoichi Naritomi, Minoru Yasuda, Minoru Okada
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:5261-5270
Type 5 17β-hydroxysteroid dehydrogenase (17β-HSD5), also known as aldo-keto reductase 1C3 (AKR1C3), is a member of the aldo-keto reductase superfamily of enzymes and is expressed in the human prostate. One of the main functions of 17β-HSD5 is to c
Autor:
Kazushiro Kawaguchi, Katsuyoshi Hashine, Hidehisa Noguchi, Karim Fizazi, Mary B. Todd, Hiro-omi Kanayama, Hisashi Hasumi, Tomohiro Tsuchiya, Namphuong Tran, Fuminori Sato, Hiroaki Matsumoto, Hirotsugu Uemura, Kentaro Enjo, Hiroyoshi Suzuki, Mototsugu Oya, Nobuaki Matsubara, Satoshi Fukasawa
Publikováno v:
Journal of Clinical Oncology. 36:286-286
286 Background: Patients with high-risk mHNPC have a poor prognosis. In Japan, mHNPC accounts for approximately 10% of newly diagnosed prostate cancers. AAP was approved for the treatment of castration-resistant prostate cancer in Japan in July 2014.
Autor:
Sadao Kuromitsu, Edwina Baskin-Bey, Tatsuya Niimi, Kazushi Watanabe, Kentaro Enjo, Yoshiteru Kamiyama, Takashi Furutani, Aya Kikuchi, Marten Heeringa, Hidenori Azami, Taoufik Ouatas
Publikováno v:
Investigational new drugs. 32(5)
Background Aldo-keto reductase 1C3 [AKR1C3;17β-hydroxysteroid dehydrogenase type 5 (17βHSD5)], plays a crucial role in persistent production of androgens despite castration, by catalysing conversion of the adrenal androgens dehydroepiandrosterone a
Publikováno v:
The Journal of Physical Chemistry B. 101:10661-10665
The novel solvent-viscosity dependence of the time-resolved reaction-yield-detected magnetic resonance (RYDMR) spectra is observed for the polymethylene-linked biradical generated in the photoinduced intramolecular electron-transfer reaction between
Publikováno v:
Applied Magnetic Resonance. 12:423-430
The spin dynamics of the intermediate radical ion pairs formed in the intra-and intermolecular electron transfer reactions between N,N-dimethylaniline and phenanthrene is studied by employing the polymethylene-linked and nonlinked systems. Reaction-y
Publikováno v:
Applied Magnetic Resonance. 12:411-422
Three different RYDMR (reaction-yield detected magnetic resonance) techniques, photoconductivity detected magnetic resonance (PCDMR), transient-absorption detected magnetic resonance (ADMR) and delayed fluorescence detected magnetic resonance (DFDMR)
Autor:
Osamu, Ishimoto, Chikashi, Kawahara, Kentaro, Enjo, Masuo, Obinata, Toshihiro, Nukiwa, Shuntaro, Ikawa
Publikováno v:
Cancer research. 62(3)
p73, a recently identified gene highly homologous to p53, can transactivate p53 target genes and induce apoptosis. Here we report the identification of an NH(2)-terminal truncated isoform of human p73, DeltaNp73, which is capable of suppressing p53-
Autor:
Takashi Furutani, Hidenori Azami, Yoshiteru Kamiyma, Kentaro Enjo, Sadao Kuromitsu, Tatsuya Nimi, Aya Kikuchi
Publikováno v:
Journal of Clinical Oncology. 31:5046-5046
5046 Background: Aldo–keto reductase 1C3 (AKR1C3), also known as type 5, 17β-hydroxysteroid dehydrogenase, is reported to be highly expressed in human normal prostate and prostate cancer (PC) and the expression increases along with increasing mali