Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kentaro, Shimada"'
Autor:
Koki Fujimori, Shuichiro Yamanaka, Kentaro Shimada, Kenji Matsui, Shiho Kawagoe, Takao Kuroda, Atsushi Ikeda, Makoto Inoue, Eiji Kobayashi, Takashi Yokoo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Porcine organs and human induced pluripotent stem cell (iPSC)-derived organoids as alternative organs for human transplantation have garnered attention, but both face technical challenges. Interspecies chimeric organ production using human i
Externí odkaz:
https://doaj.org/article/75ba1d4fd6a14d208b1c648b2db3c7d9
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice
Autor:
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In mammals, females undergo reproductive cessation with age, whereas male fertility gradually declines but persists almost throughout life. However, the detailed effects of ageing on germ cells during and after spermatogenesis, in the testis
Externí odkaz:
https://doaj.org/article/623ca58762e34a14a21188196ebbee61
Autor:
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M. Matzuk, Daniel H. Wreschner, Masahito Ikawa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The mammalian spermatozoa produced in the testis require functional maturation in the epididymis for their full competence. Epididymal sperm maturation is regulated by lumicrine signalling pathways in which testis-derived secreted signals re
Externí odkaz:
https://doaj.org/article/4d3208f2e95d4df484e1e1afd10588b0
Autor:
Yuka Inage, Koki Fujimori, Masaki Takasu, Kenji Matsui, Yoshitaka Kinoshita, Keita Morimoto, Nagisa Koda, Shutaro Yamamoto, Kentaro Shimada, Takashi Yokoo, Eiji Kobayashi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4793 (2024)
Fetal organs and organoids are important tools for studying organ development. Recently, porcine organs have garnered attention as potential organs for xenotransplantation because of their high degree of similarity to human organs. However, to meet t
Externí odkaz:
https://doaj.org/article/f303a66eaff84d899cd71e39033a753a
Autor:
Kentaro, SHIMADA
Publikováno v:
教育学論集. 75:65-80
While the expansion of basic education opportunities has progressed to guarantee quality education for all, disparities in school enrollment have become apparent. There is an urgent need to support marginalized children to build a society of diversit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::621a0d108d7d1a542e5a5857de5b149e
http://hdl.handle.net/10911/00041004
http://hdl.handle.net/10911/00041004
Publikováno v:
Crystals, Vol 10, Iss 12, p 1156 (2020)
The α′ martensite of Ti-15mass%Nb alloy exhibits high internal friction with high damping properties. However, its structure is smoother than the α + β structure. Therefore, a hardened surface layer is required for abrasion resistance. This stud
Externí odkaz:
https://doaj.org/article/f853e6c57d4a4535ba8a0137fd3d132a
Autor:
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Sperm acrosomal membrane proteins, such as Izumo sperm–egg fusion 1 (IZUMO1) and sperm acrosome-associated 6 (SPACA6), play essential roles in mammalian gamete binding or fusion. How their biosynthesis is regulated during spermiogenesis has largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0192572097c3af17ab9ca6cc6cad212
https://doi.org/10.1073/pnas.2207263120
https://doi.org/10.1073/pnas.2207263120
Autor:
Satoko Sakamoto, Dean Thumkeo, Hiroshi Ohta, Zhen Zhang, Shuangru Huang, Pakorn Kanchanawong, Takayoshi Fuu, Sadanori Watanabe, Kentaro Shimada, Yoshitaka Fujihara, Shosei Yoshida, Masahito Ikawa, Naoki Watanabe, Mitinori Saitou, Shuh Narumiya
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2004874 (2018)
Formin is one of the two major classes of actin binding proteins (ABPs) with nucleation and polymerization activity. However, despite advances in our understanding of its biochemical activity, whether and how formins generate specific architecture of
Externí odkaz:
https://doaj.org/article/d970502460524e6db266d670942d5be9
Autor:
Hirofumi Hioki, Takashi Miura, Yusuke Miyashita, Hirohiko Motoki, Kentaro Shimada, Masanori Kobayashi, Hiroyuki Nakajima, Hikaru Kimura, Eiichiro Mawatari, Hiroshi Akanuma, Toshio Sato, Souichirou Ebisawa, Uichi Ikeda
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 7, Iss C, Pp 76-81 (2015)
Background: CHADS2 or CHA2DS2-VASc score is used for prediction of stroke in patients with atrial fibrillation (AF). Recently, CHADS2 score is reported to have prognostic value in acute coronary syndrome without AF. However, clinical validation of CH
Externí odkaz:
https://doaj.org/article/2f6e5950da9a4d99af00e13e7d4eb688
Autor:
Teruaki Oku, Kentaro Shimada, Hiroki Kenmotsu, Yusuke Ando, Chisato Kurisaka, Rikio Sano, Makoto Tsuiji, Shinya Hasegawa, Tetsuya Fukui, Tsutomu Tsuji
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3961 (2018)
It has recently been recognized that inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), upregulate the secretion of matrix metalloproteinase-9 (MMP-9) from cancer cells and thereby promote peritoneal dissemination. In this study, we f
Externí odkaz:
https://doaj.org/article/a78cb114b2b14f3fa4a82ae9c44a9e6b