Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kentaro, Sakamoto"'
Autor:
Kentaro Sakamoto, Mitsunobu Kawamura, Takayuki Watanabe, Keiko Ashidate, Takahide Kohro, Akira Tanaka, Yasumichi Mori, Motoki Tagami, Tsutomu Hirano, Tsutomu Yamazaki, Teruo Shiba, RESEARCH Study Group
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background Lowering cholesterol levels decreases the risk of atherosclerotic diseases. Effective ways to stably reduce LDL-C level are warranted in type 2 diabetic patients, a high-risk population for CVD, with various anti-diabetic therapeu
Externí odkaz:
https://doaj.org/article/8bec447d32e84c158c795be195194716
Autor:
Yasushi Kawasaki, Eriko Yokobayashi, Kentaro Sakamoto, Eri Tenma, Haruka Takaki, Yuki Chiba, Tomomi Otashiro, Mai Ishihara, Sei Yonezawa, Akinori Sugiyama, Yasuhiro Natori
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 200-204 (2015)
This study aimed to elucidate the protective potential of angiostatin in inflamed endothelial cells in culture. We assessed the effect of angiostatin on the expression of ICAM-1 and eNOS. Angiostatin prevented IL-1β-induced down-regulation of eNOS e
Externí odkaz:
https://doaj.org/article/ad069e013d014c788497db2800099dce
Autor:
Kentaro Sakamoto, Mitsunobu Kawamura, Takahide Kohro, Masao Omura, Takayuki Watanabe, Keiko Ashidate, Toshiyuki Horiuchi, Hidehiko Hara, Nobuo Sekine, Rina Chin, Motoyoshi Tsujino, Toru Hiyoshi, Motoki Tagami, Akira Tanaka, Yasumichi Mori, Takeshi Inazawa, Tsutomu Hirano, Tsutomu Yamazaki, Teruo Shiba, RESEARCH Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138332 (2015)
There exists a subpopulation of T2DM in whom first-line doses of statin are insufficient for optimally reducing LDL-C, representing a major risk of CVD. The RESEARCH study focuses on LDL-C reduction in this population along with modifications of the
Externí odkaz:
https://doaj.org/article/f08c265f61aa4a2fb989da8e15025dbf
Autor:
Koichi Ogami, Yuka Oishi, Kentaro Sakamoto, Mayu Okumura, Ryota Yamagishi, Takumi Inoue, Masaya Hibino, Takuto Nogimori, Natsumi Yamaguchi, Kazuya Furutachi, Nao Hosoda, Hiroto Inagaki, Shin-ichi Hoshino
Publikováno v:
Cell Reports. 41:111548
Translation of 5' terminal oligopyrimidine (TOP) mRNAs encoding the protein synthesis machinery is strictly regulated by an amino-acid-sensing mTOR pathway. However, its regulatory mechanism remains elusive. Here, we demonstrate that TOP mRNA transla
Publikováno v:
YAKUGAKU ZASSHI. 139:519-523
Recently, we considered the term 'integrated community care system' and aimed to play a role in the process by joining various healthcare occupations as part of this new integrated system. Given our company's ties with people involved in a range of o
Autor:
Shinsuke Noso, Hiroshi Ikegami, Yuko Kondo, Teruo Shiba, Takako Mitsumatsu, Kentaro Sakamoto, Sumie Okahata
Publikováno v:
Endocrine Journal. 66:295-300
Therapeutic blocking antibodies against programmed death 1 (PD1) and cytotoxic T-lymphocyte antigen 4 (CTLA4) are applied for advanced cancer therapy, but induce a wide range of immune-related adverse events. In our recent case of a 52-year-old femal
Autor:
Takako Mitsumatsu, Shoji Tanaka, Yuko Kondo, Sumie Okahata, Kentaro Sakamoto, Teruo Shiba, Fumihiko Yagi
Publikováno v:
Interventions in Obesity & Diabetes. 2
Autor:
Hiroshi Harada, Keiichi Mizutani, Sota Tsuchiya, Jun Fujiwara, Takuya Kawata, Kentaro Sakamoto
Publikováno v:
IEEJ Transactions on Electronics, Information and Systems. 136:1555-1566
Autor:
Yuko Ishizaka, Minoru Yamakado, Sumie Okahata, Masao Yano, Teruo Shiba, Takako Mitsumatsu, Kentaro Sakamoto
Publikováno v:
Diabetes. 67
Background: Increased oxidative stress plays a role in the progression of atherosclerosis. Yet only few reports in NOD. Method: Derivatives of reactive oxygen metabolites(d-ROMs) and biological antioxidant potential (BAP) were measured in 859 subject
Autor:
Teruo Shiba, Goji Tomita, Kentaro Sakamoto, Sumie Okahata, Fumihiko Yagi, Ayako Anraku, Takako Mitsumatsu, Yuko Kondo
Publikováno v:
Diabetes. 67
Background: OCT angiography (OCTA) and laser speckle flowgraphy (LSFG) are novel and noninvasive imaging modalities which could evaluate fundus blood flow quantitatively. However, the role of OCTA and LSFG as diagnostic tools has not been widely inve