Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kentaro, Kihira"'
Autor:
Daisuke Masumoto, Etsuko Nakagami-Yamaguchi, Misako Nambu, Miho Maeda, Hideko Uryu, Akira Hayakawa, Zayar Linn, Satoshi Okamura, Kosuke Kurihara, Kentaro Kihira, Takao Deguchi, Hiroki Hori
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Childhood cancer survivors lacking awareness on their potential risks of late effects often fail to seek adequate follow-up care. Patient education matching their preference is of great importance to improve their adherence to sur
Externí odkaz:
https://doaj.org/article/a403b4f853d84f9284499211226abfc7
Autor:
Vipin Shankar, Hiroki Hori, Kentaro Kihira, Lei Qi, Hidemi Toyoda, Shotaro Iwamoto, Yoshihiro Komada
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167874 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0120069.].
Externí odkaz:
https://doaj.org/article/8f92b8bfdfe34332a4558d8aa1505ab2
Autor:
Yoshihiro Komada, Yosuke Okumura, Naoki Tsuboya, Hiroki Kainuma, Vipin Shankar Chelakkot, Satoshi Okamura, Shotaro Iwamoto, Kentaro Kihira, Kosuke Kurihara, Hiroki Hori
Publikováno v:
International Journal of Hematology. 112:795-806
Minimal residual disease of leukemia may reside in the bone marrow (BM) microenvironment and escape the effects of chemotherapeutic agents. This study investigated interactions between B cell precursor (BCP)-acute lymphoblastic leukemia (ALL) cells a
Autor:
Vipin Shankar, Hiroki Hori, Kentaro Kihira, Qi Lei, Hidemi Toyoda, Shotaro Iwamoto, Yoshihiro Komada
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120069 (2015)
Neuroblastoma accounts for 15% of childhood cancer deaths and presents with metastatic disease of the bone and the bone marrow at diagnosis in 70% of the cases. Previous studies have shown that the Mesenchymal Stromal Cell (MSC) secretome, triggers m
Externí odkaz:
https://doaj.org/article/a001a0394ba54864891cff75dacd102b
Autor:
Hiroshi Fuji, Kohmei Ida, Yuka Ueda, Kenichi Yoshimura, Takaharu Oue, Yukichi Tanaka, Takuro Kazama, Tomoaki Taguchi, Tomoro Hishiki, Akiko Yokoi, Tomoko Iehara, Takeshi Inoue, Makiko Mori, Shohei Honda, Satoshi Kondo, Junya Fujimura, Sho Kurihara, Ken Hoshino, Osamu Miyazaki, Kenichiro Watanabe, Michihiro Yano, Eiso Hiyama, Kentaro Kihira, Tatsuro Tajiri, Yuichi Takama, Yuki Nogami
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38(22)
PURPOSEWe report here the outcomes and late effects of the Japanese Study Group for Pediatric Liver Tumors (JPLT)-2 protocol, on the basis of cisplatin-tetrahydropyranyl-adriamycin (CITA) with risk stratification according to the pretreatment extent
Autor:
Tomohiro Morio, Shirley Kow Yin Kham, Atsushi Manabe, Kentaro Kihira, Nan Jiang, Matthias Schwab, Chase C. Suiter, Rina Nishii, Masatoshi Takagi, Jun J. Yang, Takaya Moriyama, Karen R. Rabin, Ute Hofmann, Lie Li, Hiroki Hori, Laura J. Janke, Hidemi Toyoda, Ting-Nien Lin, Motohiro Kato, Katsuyoshi Koh, Wenjian Yang, Allen Eng Juh Yeoh
Publikováno v:
Blood. 131:2466-2474
Thiopurines (eg, 6-mercaptopurine [MP]) are highly efficacious antileukemic agents, but they are also associated with dose-limiting toxicities. Recent studies by us and others have identified inherited NUDT15 deficiency as a novel genetic cause of th
Autor:
Osamu Miyazaki, Tetsuya Takimoto, Kohmei Ida, Junya Fujimura, Yuichi Takama, Hiroshi Fuji, Ken Hoshino, Tomoro Hishiki, Makiko Mori, Tomoaki Taguchi, Eiso Hiyama, Michihiro Yano, Takuro Kazama, Yuki Aoki, Kenichi Yoshimura, Tomoko Iehara, Akiko Yokoi, Shohei Honda, Kenichiro Watanabe, Kimikazu Matsumoto, Kentaro Kihira, Yukichi Tanaka
Publikováno v:
Journal of Pediatric Surgery. 52:2051-2055
Background/purpose The purpose of this study was to clarify the role of pulmonary metastasectomy in hepatoblastomas with lung metastasis at diagnosis. We reviewed cases enrolled in the JPLT-2 study. Methods A total of 360 cases with hepatoblastoma we
Autor:
Hiroki Hori, Ting-Nien Lin, Takaya Moriyama, Atsushi Manabe, Katsuyoshi Koh, Rina Nishii, Kentaro Kihira, Motohiro Kato, Nersting Jacob, Jun J. Yang, Hiroto Inaba, Hidemi Toyoda, Kjeld Schmiegelow
Publikováno v:
Pharmacogenetics and Genomics. 27:236-239
Thiopurines [e.g. mercaptopurine (MP)] are widely used as chemotherapeutic agents in the treatment of pediatric acute lymphoblastic leukemia with dose-limiting hematopoietic toxicity. Recently, germline variants in NUDT15 have been identified as a ma
Autor:
Matthias Schwab, Cesar R. Najera, Kjeld Schmiegelow, Zhiwei Chen, Cynthia Jeffries, Ching-Hon Pui, Mary V. Relling, Tomoya Isobe, Deepa Bhojwani, Allen Eng Juh Yeoh, Takaya Moriyama, Hiroki Hori, Atsushi Manabe, Keito Hoshitsuki, Yan Lu, Rina Nishii, Kentaro Kihira, Federico Antillon Klussmann, Robert McCorkle, Wenjian Yang, Jun J. Yang, Virginia Perez-Andreu, Hiroto Inaba, Katsuyoshi Koh, Lie Li, Shirley Kow-Yin Kham, Yoshihiro Komada, Xujie Zhao, Ting-Nien Lin, Motohiro Kato, Edwynn Kean Hui Chiew, Jacob Nersting, Ute Hofmann, William E. Evans
Publikováno v:
Nature Genetics. 48:367-373
Widely used as anticancer and immunosuppressive agents, thiopurines have narrow therapeutic indices owing to frequent toxicities, partly explained by TPMT genetic polymorphisms. Recent studies identified germline NUDT15 variation as another critical
Autor:
Hiroki Hori, Masahiro Hirayama, Yoshihiro Komada, Takao Deguchi, Shotaro Iwamoto, Hidemi Toyoda, Kentaro Kihira
Publikováno v:
Journal of pediatric hematology/oncology. 40(8)
Recently, a new disease of lymphocyte homeostasis caused by somatic mosaicism for the RAS mutation has been discovered (known as RALD, RAS-associated leukoproliferative disorder). Since few cases have been reported in literature, the prognosis and st