Generation of bone-specific lysyl hydroxylase 2 knockout mice and their phenotypes

Autor: Kenta Tsuneizumi, Atsushi Kasamatsu, Tomoaki Saito, Reo Fukushima, Yuki Taga, Kazunori Mizuno, Masataka Sunohara, Katsuhiro Uzawa, Mitsuo Yamauchi

Publikováno v: Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101790- (2024)

Lysyl hydroxylase 2 (LH2) catalyzes the hydroxylation of lysine residues in the telopeptides of type I collagen. This modification is critical for the formation of stable hydroxylysine-aldehyde derived collagen cross-links, thus, for the stability of

Externí odkaz: https://doaj.org/article/f00a881d2d0f4b26b3db9551a84cf625

Molecular Pathogenesis of the Coronin Family: CORO2A Facilitates Migration and Invasion Abilities in Oral Squamous Cell Carcinoma

Autor: Shunichi Asai, Ikuko Kase-Kato, Katsuhiro Uzawa, Toyoyuki Hanazawa, Kenta Tsuneizumi, Sachi Oshima, Chikashi Minemura, Ayaka Koma, Atsushi Kasamatsu, Naohiko Seki

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12684, p 12684 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12684

In humans, the coronin family is composed of seven proteins containing WD-repeat domains that regulate actin-based cellular processes. Some members of the coronin family are closely associated with cancer cell migration and invasion. The Cancer Genom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872d86997dbe3c9c174113b512436968
https://www.mdpi.com/1422-0067/22/23/12684