Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kenta H T Cho"'
Autor:
Kenta H. T. Cho, Natalya Hounsell, Evelyn McClendon, Art Riddle, Basappa, Simerdeep K. Dhillon, Laura Bennet, Stephen Back, Larry S. Sherman, Alistair J. Gunn, Justin M. Dean
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16926 (2023)
Seizures are common in preterm newborns and are associated with poor neurodevelopmental outcomes. Current anticonvulsants have poor efficacy, and many have been associated with upregulation of apoptosis in the developing brain. Apigenin, a natural bi
Externí odkaz:
https://doaj.org/article/220a8542dfeb4f518cccead2bc0b706c
Autor:
Kelly Q. Zhou, Alice McDouall, Paul P. Drury, Christopher A. Lear, Kenta H. T. Cho, Laura Bennet, Alistair J. Gunn, Joanne O. Davidson
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7121 (2021)
Seizures are common in newborn infants with hypoxic-ischemic encephalopathy and are highly associated with adverse neurodevelopmental outcomes. The impact of seizure activity on the developing brain and the most effective way to manage these seizures
Externí odkaz:
https://doaj.org/article/6977db697d7a4a5996e99c0c7c50854c
Publikováno v:
Pediatrics International. 62:770-778
Therapeutic hypothermia is now well established to partially reduce disability in term and near-term infants with moderate-severe hypoxic-ischemic encephalopathy. Preclinical and clinical studies have confirmed that current protocols for therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf6fa912572ff826028a21ea6fea7ab
https://doi.org/10.1111/ped.14215
https://doi.org/10.1111/ped.14215
Autor:
Kenta H T Cho, Christopher A. Lear, Laura Bennet, Kelly Q Zhou, Alice McDouall, Paul P. Drury, Joanne O. Davidson, Alistair J. Gunn
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7121, p 7121 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 7121, p 7121 (2021)
Seizures are common in newborn infants with hypoxic-ischemic encephalopathy and are highly associated with adverse neurodevelopmental outcomes. The impact of seizure activity on the developing brain and the most effective way to manage these seizures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6963449a014533a36631304337ed653d
https://pubmed.ncbi.nlm.nih.gov/34281174
https://pubmed.ncbi.nlm.nih.gov/34281174
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6593, p 6593 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6593, p 6593 (2021)
Volume 22
Issue 12
Background: Toll-like receptor (TLR) agonists are key immunomodulatory factors that can markedly ameliorate or exacerbate hypoxic–ischemic brain injury. We recently demonstrated that central infusion of the TLR7 agonist Gardiquimod (GDQ) following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f56d08995534f0b5e61b2b39c086a8c
http://europepmc.org/articles/PMC8234830
http://europepmc.org/articles/PMC8234830
Autor:
Kenta H T Cho, Mhoyra Fraser, Luke Weaver-Mikaere, Joanne O. Davidson, Simerdeep K Dhillon, Lotte G. van den Heuij, Laura Bennet, Guido Wassink, Alistair J. Gunn, Bing Xu, Sam Mathai, Robert Galinsky
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Preterm brain injury is highly associated with inflammation, which is likely related in part to sterile responses to hypoxia-ischemia. We have recently shown that neuroprotection with inflammatory pre-conditioning in the immature brain is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfda8e7bedbde97a444d9278af0b23f
http://link.springer.com/article/10.1038/s41598-019-45872-y
http://link.springer.com/article/10.1038/s41598-019-45872-y
Autor:
Guido Wassink, Kenta H T Cho, Mhoyra Fraser, Laura Bennet, Joanne O. Davidson, Simerdeep J Dhillon, Justin M. Dean, Alistair J. Gunn
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 318(2)
Activation of Toll-like receptors (TLRs) after hypoxic-ischemic brain injury can exacerbate injury but also alleviate cell loss, as recently demonstrated with the TLR7 agonist Gardiquimod (GDQ). However, TLR agonists also modulate vascular function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0198c46d3e909603b5cb951f34a3d3
https://pubmed.ncbi.nlm.nih.gov/31913689
https://pubmed.ncbi.nlm.nih.gov/31913689