Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kent W. Jorgenson"'
Autor:
Jamie E. Hibbert, Kent W. Jorgenson, Wenyuan G. Zhu, Nathaniel D. Steinert, Troy A. Hornberger
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102574- (2023)
Summary: The ability to measure the in vivo rate of protein degradation is a major limitation in numerous fields of biology. Here, we present a protocol for quantifying this rate in mice using a pulse-chase technique that utilizes an azide-bearing no
Externí odkaz:
https://doaj.org/article/e596c15af03d4589a4b8f99f4b7cab7c
Autor:
Nathaniel D. Steinert, Kent W. Jorgenson, Kuan-Hung Lin, Jake B. Hermanson, Jake L. Lemens, Troy A. Hornberger
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106526- (2023)
Summary: Skeletal muscle size is controlled by the balance between protein synthesis and protein degradation. Given the essential role of skeletal muscle in maintaining a high quality of life, understanding the mechanisms that modulate this balance a
Externí odkaz:
https://doaj.org/article/f350e5a34bf94357b778af9c6864303c
Publikováno v:
Cells, Vol 12, Iss 24, p 2811 (2023)
The maintenance of skeletal muscle mass plays a fundamental role in health and issues associated with quality of life. Mechanical signals are one of the most potent regulators of muscle mass, with a decrease in mechanical loading leading to a decreas
Externí odkaz:
https://doaj.org/article/f1c55d416e1c49388712e1b965270770
Autor:
Wenyuan G. Zhu, Jamie E. Hibbert, Kuan Hung Lin, Nathaniel D. Steinert, Jake L. Lemens, Kent W. Jorgenson, Sarah M. Newman, Dudley W. Lamming, Troy A. Hornberger
Publikováno v:
Cells, Vol 10, Iss 9, p 2459 (2021)
This study describes a mouse model of progressive resistance exercise that utilizes a full-body/multi-joint exercise (weight pulling) along with a training protocol that mimics a traditional human paradigm (three training sessions per week, ~8–12 r
Externí odkaz:
https://doaj.org/article/a8c60c5da2fe40e0b413a2e752c319a0
Publikováno v:
Cells, Vol 9, Iss 7, p 1658 (2020)
The maintenance of skeletal muscle mass plays a critical role in health and quality of life. One of the most potent regulators of skeletal muscle mass is mechanical loading, and numerous studies have led to a reasonably clear understanding of the mac
Externí odkaz:
https://doaj.org/article/df43b930c200418e9620cddf67148f9e
Publikováno v:
Cells
Cells, Vol 9, Iss 1658, p 1658 (2020)
Cells, Vol 9, Iss 1658, p 1658 (2020)
The maintenance of skeletal muscle mass plays a critical role in health and quality of life. One of the most potent regulators of skeletal muscle mass is mechanical loading, and numerous studies have led to a reasonably clear understanding of the mac
Autor:
Jamie E. Hibbert, Kuan-Hung Lin, Wenyuan G. Zhu, Dudley W. Lamming, Troy A. Hornberger, Sarah M. Newman, Nathaniel D. Steinert, Kent W. Jorgenson, Jake L. Lemens
Publikováno v:
Cells
Volume 10
Issue 9
Cells, Vol 10, Iss 2459, p 2459 (2021)
Volume 10
Issue 9
Cells, Vol 10, Iss 2459, p 2459 (2021)
This study describes a mouse model of progressive resistance exercise that utilizes a full-body/multi-joint exercise (weight pulling) along with a training protocol that mimics a traditional human paradigm (3 training sessions per week, ∼8-12 repet
Autor:
Kent W. Jorgenson, Troy A. Hornberger
Publikováno v:
Exercise and sport sciences reviews. 47(4)
Publikováno v:
Curr Opin Neurobiol
The actin cytoskeleton in neurons plays critical roles in axonal growth and synaptic organization. Until recently, most studies on axonal actin were limited to terminal growth cones or synapses, whereas the organization of actin along the shaft of th
Autor:
Kent W Jorgenson, Jamie E Hibbert, Ramy KA Sayed, Anthony N Lange, Joshua S Godwin, Paulo HC Mesquita, Bradley A Ruple, Mason C McIntosh, Andreas N Kavazis, Michael D Roberts, Troy A Hornberger
Publikováno v:
eLife, Vol 12 (2024)
An increase in mechanical loading, such as that which occurs during resistance exercise, induces radial growth of muscle fibers (i.e. an increase in cross-sectional area). Muscle fibers are largely composed of myofibrils, but whether radial growth is
Externí odkaz:
https://doaj.org/article/4dced3afb22343c3a3c679665fb37639