Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Kent T, HayGlass"'
Autor:
Caroline Graham, Rishma Chooniedass, William P Stefura, Allan B Becker, Malcolm R Sears, Stuart E Turvey, Piush J Mandhane, Padmaja Subbarao, CHILD Study Investigators, Kent T HayGlass
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177813 (2017)
Changes in maternal innate immunity during healthy human pregnancy are not well understood. Whether basal immune status in vivo is largely unaffected by pregnancy, is constitutively biased towards an inflammatory phenotype (transiently enhancing host
Externí odkaz:
https://doaj.org/article/035c6e6918814bc089e44461058a07c0
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149942 (2016)
Cardiac surgery induces many physiologic changes including major inflammatory and sympathetic nervous system responses. Here, we conducted a single-centre pilot study to generate hypotheses on the potential immune impact of adding high spinal anaesth
Externí odkaz:
https://doaj.org/article/230a2bccf7d54edcab591bab88b07398
Autor:
Tobias R. Kollmann, Jeremy A. Scott, Teresa To, M.B. Azad, Theo J. Moraes, Michael Brauer, Piush J. Mandhane, Thomas Eiwegger, Allan B. Becker, Andrew J. Sandford, A. D. Befus, Frances Silverman, Catherine Laprise, Edith Chen, Richard G. Hegele, Scott J. Tebbutt, Padmaja Subbarao, W.Y.W. Lou, Anita L. Kozyrskyj, Felix Ratjen, Peter D. Paré, A.B. Becker, J.R. Brook, D. L. Holness, Meghan B. Azad, P. J. Mandhane, Joseph Macri, Sharon D. Dell, T.J. Moraes, Clare D. Ramsey, Malcolm R. Sears, M.R. Sears, Q. L. Duan, Wendy Y. W. Lou, Stuart E. Turvey, Brittany A. Matenchuk, Sukhpreet K Tamana, P. Subbarao, Sonia S. Anand, A.L. Kozyrskyj, Michael M Cyr, S.E. Turvey, Hartmut Grasemann, James A. Scott, Timothy K. Takaro, Perry Hystad, Gregory E. Miller, Kent T. HayGlass, Judah A. Denburg, Denise Daley, Elinor Simons, Diana L. Lefebvre, Michael S. Kobor
Publikováno v:
Sleep Medicine. 59:24-32
Rationale Sleep duration is critical to growth, learning, and immune function development in infancy. Strategies to ensure that national recommendations for sleep duration in infants are met require knowledge of perinatal factors that affect infant s
Autor:
Jungang Xie, Larisa C Lotoski, Rishma Chooniedass, Ruey-Chyi Su, F Estelle R Simons, Joel Liem, Allan B Becker, Jude Uzonna, Kent T HayGlass
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45377 (2012)
Food allergies, and peanut allergy in particular, are leading causes of anaphylactic fatalities worldwide. The immune mechanisms that underlie food allergy remain ill-defined and controversial, in part because studies in humans typically focus on ana
Externí odkaz:
https://doaj.org/article/dc96061906fd4b90a42cd3dbd1da01ed
Autor:
Meghan B Azad, Yuri Lissitsyn, Gregory E Miller, Allan B Becker, Kent T HayGlass, Anita L Kozyrskyj
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38669 (2012)
Lower socioeconomic status (SES) is consistently associated with poor health, yet little is known about the biological mechanisms underlying this inequality. In children, we examined the impact of early-life SES trajectories on the intensity of globa
Externí odkaz:
https://doaj.org/article/ba8e83346ad5482abc2d53340da24025
Autor:
Renée N Douville, Yuriy Lissitsyn, Aaron F Hirschfeld, Allan B Becker, Anita L Kozyrskyj, Joel Liem, Nathalie Bastien, Yan Li, Rachel E Victor, Mehtab Sekhon, Stuart E Turvey, Kent T HayGlass
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12087 (2010)
A broad variety of natural environmental stimuli, genotypic influences and timing all contribute to expression of protective versus maladaptive immune responses and the resulting clinical outcomes in humans. The role of commonly co-segregating Toll-l
Externí odkaz:
https://doaj.org/article/6bc7b93ae6604761a06750567f8dc153
Autor:
Larisa C Lotoski, F Estelle R Simons, Rishma Chooniedass, Joel Liem, Isha Ostopowich, Allan B Becker, Kent T HayGlass
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11192 (2010)
Food allergies are a major component of the burden of allergic disease. Accurate risk assessment for prediction of future clinical reactivity or clinical tolerance is limited by currently available techniques. Recent studies suggest that constitutive
Externí odkaz:
https://doaj.org/article/812ccb5447794c5b86b6f9fd1af89a10
Autor:
Martin P Alphonse, Arash S Saffar, Lianyu Shan, Kent T HayGlass, F Estelle R Simons, Abdelilah S Gounni
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1921 (2008)
The high affinity IgE receptor, Fc epsilonRI, plays a key role in the immunological pathways involved in allergic asthma. Previously we have demonstrated that human neutrophils isolated from allergic asthmatics express a functional Fc epsilonRI, and
Externí odkaz:
https://doaj.org/article/aa0c14493d7b4c9d98eedfa6a289ab0b
Publikováno v:
Immunity, Inflammation and Disease. 5:364-372
Introduction Obesity during pregnancy is associated with meta-inflammation and an increased likelihood of clinical complications. Surgery results in intense, acute inflammatory responses in any individual. Because obese individuals exhibit constituti
Autor:
Jordan W. Squair, David D.W. Twa, Kirill Zaslavsky, Lynn A Raymond, Alexandra Kuzyk, Mark J Eisenberg, Jennifer X Ji, Ève-Reine Gagné, Norman D. Rosenblum, Xin Wang, Patrick E. Steadman, Ayan K. Dey, James F Lewis, Peter J Margetts, Kent T HayGlass, Michael A. Skinnider, D Alan Underhill
Publikováno v:
CMAJ Open. 5:E308-E314
Background Combined MD/PhD programs provide a structured path for physician-scientist training, but assessment of their success within Canada is limited by a lack of quantitative data. We collected outcomes data for graduates of Canadian MD/PhD progr