Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kent SAK"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Extracellular ATP and adenosine are neuromodulators that regulate numerous neuronal functions in the brain. Neuronal activity and brain insults such as ischemic and traumatic injury upregulate these neuromodulators, which exert their effects by activ
Externí odkaz:
https://doaj.org/article/510ce85823cb4570a6016bb9be614d22
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 3, Pp 298-303 (2019)
The Janus kinase 1/3 inhibitor tofacitinib has demonstrated an antipruritic effect in two phase III studies in psoriasis. However, the mechanisms behind this antipruritic effect are still unknown. We presently investigated whether tofacitinib affects
Externí odkaz:
https://doaj.org/article/a3b7d3fce0bf457882754ad229b78c89
Autor:
Daisuke Yamamuro, Manabu Takahashi, Shuichi Nagashima, Tetsuji Wakabayashi, Hisataka Yamazaki, Akihito Takei, Shoko Takei, Kent Sakai, Ken Ebihara, Yusaku Iwasaki, Toshihiko Yada, Shun Ishibashi
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234439 (2020)
Disturbance of circadian rhythms underlies various metabolic diseases. Constant light exposure (LL) is known to disrupt both central and peripheral circadian rhythms. Here, we attempted to determine whether the effects of LL are different between var
Externí odkaz:
https://doaj.org/article/c9cfb78d74064476bf1ae474b21160fd
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 9, Pp 855-861 (2018)
Skin thermal changes modulate itch sensitivity. However, the mechanisms of this modulation are still unclear. Using mouse models of acute and chronic itch, we investigated whether local innocuous thermal stimulation of the skin alters itch sensitivit
Externí odkaz:
https://doaj.org/article/8cb22cfc98814c6c8f13b6a1c72b35f2
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 10, Pp 901-902 (2019)
Abstract is missing (Short Communication)
Externí odkaz:
https://doaj.org/article/b139af0a53a54822912b8ed3e579d6a9
Autor:
Shuichi Nagashima, Hiroaki Yagyu, Ryuichi Tozawa, Fumiko Tazoe, Manabu Takahashi, Tetsuya Kitamine, Daisuke Yamamuro, Kent Sakai, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Akira Honda, Shun Ishibashi
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 5, Pp 998-1005 (2015)
Squalene synthase (SS) catalyzes the biosynthesis of squalene, the first specific intermediate in the cholesterol biosynthetic pathway. To test the feasibility of lowering plasma cholesterol by inhibiting hepatic SS, we generated mice in which SS is
Externí odkaz:
https://doaj.org/article/7b48d2ba7b554bd8aaf864108108d737
Autor:
Kent Sakai, Masaki Igarashi, Daisuke Yamamuro, Taichi Ohshiro, Shuichi Nagashima, Manabu Takahashi, Bolormaa Enkhtuvshin, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Shun Ishibashi
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2033-2040 (2014)
Hydrolysis of intracellular cholesteryl ester (CE) is the rate-limiting step in the efflux of cholesterol from macrophage foam cells. In mouse peritoneal macrophages (MPMs), this process is thought to involve several enzymes: hormone-sensitive lipase
Externí odkaz:
https://doaj.org/article/53ac1491a9844d5ca276afa472350ef2
Autor:
Motohiro Sekiya, Daisuke Yamamuro, Taichi Ohshiro, Akira Honda, Manabu Takahashi, Masayoshi Kumagai, Kent Sakai, Shuichi Nagashima, Hiroshi Tomoda, Masaki Igarashi, Hiroaki Okazaki, Hiroaki Yagyu, Jun-ichi Osuga, Shun Ishibashi
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2082-2092 (2014)
An excess of cholesterol and/or oxysterols induces apoptosis in macrophages, contributing to the development of advanced atherosclerotic lesions. In foam cells, these sterols are stored in esterified forms, which are hydrolyzed by two enzymes: neutra
Externí odkaz:
https://doaj.org/article/8b2678c6d9294aa8b1e9b627bef59173
Publikováno v:
Acta Dermato-Venereologica, Vol 97, Iss 6, Pp 739-740 (2017)
Externí odkaz:
https://doaj.org/article/702f81ecc68a4866901c57d79541ab4d
Autor:
Kent SAK; Department of Speech, Language & Hearing Sciences, Auburn University, Auburn, Alabama., Fletcher TL; Department of Speech, Language & Hearing Sciences, Auburn University, Auburn, Alabama., Morgan A; Department of Speech, Language & Hearing Sciences, Auburn University, Auburn, Alabama., Morton M; School of Kinesiology, Auburn University, Auburn, Alabama., Hall RJ; Department of Speech, Language & Hearing Sciences, Auburn University, Auburn, Alabama., Sandage MJ; Department of Speech, Language & Hearing Sciences, Auburn University, Auburn, Alabama. Electronic address: sandamj@auburn.edu.
Publikováno v:
Journal of voice : official journal of the Voice Foundation [J Voice] 2023 Mar 18. Date of Electronic Publication: 2023 Mar 18.