Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Kent L. Thornburg"'
Publikováno v:
Physiological Reports, Vol 11, Iss 22, Pp n/a-n/a (2023)
Abstract Cardiac metabolic substrate preference shifts at parturition from carbohydrates to fatty acids. We hypothesized that thyroid hormone (T3) and palmitic acid (PA) stimulate fetal cardiomyocyte oxidative metabolism capacity. T3 was infused into
Externí odkaz:
https://doaj.org/article/94d904ad2f4d48a2b339443411aafb19
Autor:
Hillary H. Le, Matthew W. Hagen, Samantha Louey, Hagai Tavori, Kent L. Thornburg, George D. Giraud, Monica T. Hinds, Anthony P. Barnes
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Developmental programming of chronic adverse cardiovascular health outcomes has been studied both using numerous human populations and an array of animal models. However, the mechanisms that produce transgenerational effects have been difficult to st
Externí odkaz:
https://doaj.org/article/b8f58434a82540278e8e4e07833df64d
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 12, p 497 (2023)
Introduction: The prenatal diagnosis of congenital heart disease (CHD) is a traumatic event that can cause expectant parents to experience anxiety, depression, and toxic stress. Prenatal exposure to stress may impact neonatal postoperative outcomes.
Externí odkaz:
https://doaj.org/article/0bf9a1de34bc43f39a886a9601294bde
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/7d2cc02ccc6043b39b4b9c8070096473
Autor:
Suhas Sureshchandra, Nicole E. Marshall, Randall M. Wilson, Tasha Barr, Maham Rais, Jonathan Q. Purnell, Kent L. Thornburg, Ilhem Messaoudi
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Pre-pregnancy (pregravid) obesity has been linked to several adverse health outcomes for both mother and offspring. Complications during pregnancy include increased risk for gestational diabetes, hypertension, preeclampsia, placental abruption, and d
Externí odkaz:
https://doaj.org/article/87b230db100d4a63b446d316c271c134
Autor:
Taylor B. Lawson, Devon E. Scott-Drechsel, Venkat Keshav Chivukula, Sandra Rugonyi, Kent L. Thornburg, Monica T. Hinds
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 13 (2018)
Congenital heart defects (CHDs) represent the most common form of human birth defects; approximately one-third of heart defects involve malformations of the outflow tract (OFT). Maternal diabetes increases the risk of CHD by 3–5 fold. During heart
Externí odkaz:
https://doaj.org/article/d69716ca41814798b8a62f29837eb620
Autor:
Monique Y. Rennie, Stephanie Stovall, James P. Carson, Michael Danilchik, Kent L. Thornburg, Sandra Rugonyi
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 4, Iss 4, p 24 (2017)
Blood flow is critical for normal cardiac development. Hemodynamic stimuli outside of normal ranges can lead to overt cardiac defects, but how early heart tissue remodels in response to altered hemodynamics is poorly understood. This study investigat
Externí odkaz:
https://doaj.org/article/9bf56633ae904471b121655ccfe5d602
Autor:
Johan G. Eriksson, Jill Gelow, Kent L. Thornburg, Clive Osmond, Markku Laakso, Matti Uusitupa, Virpi Lindi, Eero Kajantie, David J. P. Barker
Publikováno v:
International Journal of Pediatrics, Vol 2012 (2012)
Obesity is programmed in utero and small babies generally have small placentas. In some circumstances, an undernourished fetus can expand its placental surface to extract more nutrients. We hypothesize that this results in an imbalanced nutrient supp
Externí odkaz:
https://doaj.org/article/878f32b7d7ed417dbf71ff90b2faae91
Autor:
Ornella Manfra, Samantha Louey, Sonnet S. Jonker, Harmonie Perdreau‐Dahl, Michael Frisk, George D. Giraud, Kent L. Thornburg, William E. Louch
Publikováno v:
The Journal of Physiology.
Publikováno v:
Reproductive Sciences. 29:2908-2920
Understanding, predicting, and preventing pregnancy disorders have been a major research target. Nonetheless, the lack of progress is illustrated by research results related to preeclampsia and other hypertensive pregnancy disorders. These remain a m