Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Kent L. Hill"'
Autor:
Michelle M. Shimogawa, Angeline S. Wijono, Hui Wang, Jiayan Zhang, Jihui Sha, Natasha Szombathy, Sabeeca Vadakkan, Paula Pelayo, Keya Jonnalagadda, James Wohlschlegel, Z. Hong Zhou, Kent L. Hill
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Motility of pathogenic protozoa depends on flagella (synonymous with cilia) with axonemes containing nine doublet microtubules (DMTs) and two singlet microtubules. Microtubule inner proteins (MIPs) within DMTs influence axoneme stability and
Externí odkaz:
https://doaj.org/article/743b9fffbf724d74a32dfd2a0cc1187a
Autor:
Jiayan Zhang, Hui Wang, Simon Imhof, Xueting Zhou, Shiqing Liao, Ivo Atanasov, Wong H. Hui, Kent L. Hill, Z. Hong Zhou
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract Eukaryotic flagella (synonymous with cilia) rely on a microtubule-based axoneme, together with accessory filaments to carryout motility and signaling functions. While axoneme structures are well characterized, 3D ultrastructure of accessory
Externí odkaz:
https://doaj.org/article/38ab5ac8917f4d0eae531c22cc5973cf
Autor:
Sebastian Shaw, Stephanie F. DeMarco, Ruth Rehmann, Tanja Wenzler, Francesca Florini, Isabel Roditi, Kent L. Hill
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Trypanosoma brucei probably relies on chemotactic signals for movement through tsetse fly tissues, but the molecular basis is unknown. Here, the authors show that flagellar cAMP signaling is required for traversal of the peritrophic matrix and that,
Externí odkaz:
https://doaj.org/article/30f4254f1f9248b0a285b1c1494715d5
Autor:
Daniel E. Vélez-Ramírez, Michelle M. Shimogawa, Sunayan S. Ray, Andrew Lopez, Shima Rayatpisheh, Gerasimos Langousis, Marcus Gallagher-Jones, Samuel Dean, James A. Wohlschlegel, Kent L. Hill
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Sleeping sickness is a neglected tropical disease caused by the protozoan parasite Trypanosoma bruceiT. brucei
Externí odkaz:
https://doaj.org/article/b340ee2156a843d18968fdfaf6f8b347
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT To complete its infectious cycle, the protozoan parasite Trypanosoma brucei must navigate through diverse tissue environments in both its tsetse fly and mammalian hosts. This is hypothesized to be driven by yet unidentified chemotactic cues.
Externí odkaz:
https://doaj.org/article/d40f4450dcd244a9a7582a541f6eeb9e
Autor:
Jiayan Zhang, Hui Wang, Simon Imhof, Xueting Zhou, Shiqing Liao, Ivo Atanasov, Wong H. Hui, Kent L. Hill, Z. Hong Zhou
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/5f461e9fa61042228930673ca0f09d90
Autor:
Simon Imhof, Jiayan Zhang, Hui Wang, Khanh Huy Bui, Hoangkim Nguyen, Ivo Atanasov, Wong H Hui, Shun Kai Yang, Z Hong Zhou, Kent L Hill
Publikováno v:
eLife, Vol 8 (2019)
The 96-nm axonemal repeat includes dynein motors and accessory structures as the foundation for motility of eukaryotic flagella and cilia. However, high-resolution 3D axoneme structures are unavailable for organisms among the Excavates, which include
Externí odkaz:
https://doaj.org/article/ae870c1baf4a4029ab51a487dfc3a810
Autor:
Michelle M. Shimogawa, Angeline S. Wijono, Hui Wang, Jiayan Zhang, Jihui Sha, Natasha Szombathy, Sabeeca Vadakkan, Paula Pelayo, Keya Jonnalagadda, James Wohlschlegel, Z. Hong Zhou, Kent L. Hill
Motility of pathogenic protozoa depends on flagella (synonymous with cilia) with axonemes containing nine doublet microtubules (DMTs) and two singlet microtubules. Microtubule inner proteins (MIPs) within DMTs influence axoneme stability and motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::706ce78396af52dc3bdc9a91235879a5
https://doi.org/10.1101/2022.11.11.516029
https://doi.org/10.1101/2022.11.11.516029
Autor:
Kent L. Hill, Breanna Walsh
Publikováno v:
Mol Microbiol
Trypanosoma brucei and other African trypanosomes are vector-borne parasites that cause substantial human suffering across sub-Saharan Africa. The T. brucei life cycle is punctuated by numerous developmental stages, each occurring in a specific envir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b39b78bec262c9c1d1a848142c90c0d
https://doi.org/10.1111/mmi.14682
https://doi.org/10.1111/mmi.14682
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005272 (2015)
Externí odkaz:
https://doaj.org/article/f3bfa780700a402d9e9ae61eb936d70f